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Is milk thistle effective in cancer treatment?

July 11, 2007

Special issue of Integrative Cancer Therapies Journal, published by SAGE, presents summary of research on herbal supplement

Milk thistle extract, an herbal remedy since the times of the ancient Greeks and Romans, is today one of the most popular herbal supplements, with U.S. retail sales of nearly nine million dollars.




The current issue of Integrative Cancer Therapies (ICT) published by SAGE, contains a summary of current research on and clinical application of silymarin, the mixture of chemicals found in milk thistle. The special issue features new research from Morgan Stanley Children's Hospital of New York-Presbyterian and Columbia University Medical Center finding liver-protective effects for silymarin in children receiving cancer chemotherapy. Guest edited by Drs. Kara Kelly, Janice Post-White, and Elena Ladas, the issue covers the entire scope of milk thistle use in cancer treatment, as well as in fighting other diseases like hepatitis C, diabetes, and HIV, reporting on such subjects as:

* Recent advances in the use of milk thistle

* Clinical trials evaluating the safety and efficacy of milk thistle

* The molecular makeup of silymarin

* Benefits of silymarin use before and during toxic insults to the liver, including damage from alcohol; cancer chemotherapy and other drugs; solvents; and mushroom poisoning

* Direction for future research on milk thistle for cancer patients

"This special issue presents both preclinical and clinical studies demonstrating the potential role of milk thistle as an anticancer agent. No other medications or supplements are currently available that preserve liver function and provide clinical benefits," write the guest editors in their opening editorial.

"The clinical potential for a liver-protective supplement in cancer care is significant, as I've observed in many years of integrative medical practice," writes Dr. Keith Block, ICT editor. "Several chemotherapy drugs, as well as many of the other drugs cancer patients take, have extremely problematic liver toxicities. With this exclusive edition, the scientific community will have a resource to guide and inspire further research on this very interesting herbal medicine."

SAGE Publications



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Milk Thistle - Standardized Extract 120 vcaps

Milk Thistle - Standardized Extract 120 vcaps
by NATURE'S WAY

Nature's Way standardized milk thistle is a scientifically and technically advanced herbal extract standardized to 80% silymarin. Nature's Way Milk Thistle extract supports normal liver function. The active bioflavonoid complex, silymarin and it's sub- component silibinin, are powerful antioxidants in the liver and exert a protective effect against substances that may be potentially harmful to the liver.



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Milk Thistle 500 mg 100 Caps

Milk Thistle 500 mg 100 Caps
by Swanson Premium Brand

Nature's premier herbal liver tonic, milk thistle contains a powerful antioxidant flavonoid known as silymarin, which has specific protective benefits for liver tissues. Our convenient capsules deliver 500 mg of milk thistle nutrition that won't put a dent in your pocketbook. Limit 3 Bottles

Nature Made Milk Thistle Tablets, 140 mg, 50-Count Bottles (Pack of 3)

Nature Made Milk Thistle Tablets, 140 mg, 50-Count Bottles (Pack of 3)
by Nature Made

Helps maintain healthy liver function. Effectiveness supported by clinical trails. Standardized Extract: Milk Thistle Seed Extract. No artificial colors, flavors or preservatives. Milk Thistle helps to maintain healthy liver function through its antioxida

Rainbow Light Milk Thistle Plus, Food Based, Tablets, 120 tablets

Rainbow Light Milk Thistle Plus, Food Based, Tablets, 120 tablets
by Rainbow Light

Dietary Supplement. Comprehensive Liver Support. Advanced antioxidant protection. Naturally extracted milk thistle. Targeted botanical and nutrient support of overall liver health. Milk Thistle Plus formula supports liver health with: Comprehensive liver support--from nutrients and botanicals that promote liver health, including 1,500 mg of milk thistle; Advanced antioxidant protection--featuring, silymarin from milk thistle, plus mixed carotenoids to guard the liver from free radical oxidation; Naturally extracted milk thistle--using no harsh solvents, for superior purity. Guarantee: 100% natural and VegeGuard screened for vegans; no trace animal ingredients. Free of artificial colors, flavors, sweeteners and preservatives. Hypoallergenic, Contains no sugar, lactose, soy, wheat, gluten...

Milk Thistle 250 mg 120 Caps

Milk Thistle 250 mg 120 Caps
by Swanson Superior Herbs

Nature's premier herbal liver tonic, milk thistle contains a powerful antioxidant flavonoid known as silymarin, which has specific protective benefits for liver tissues. Our convenient capsules combine 250 mg of guaranteed-potency milk thistle (standardized to 80 percent silymarin) with 250 mg of milk thistle powder. Limit 3 Bottles

Spring Valley - Milk Thistle, 90 Softgels, 1000 mg

Spring Valley - Milk Thistle, 90 Softgels, 1000 mg
by US Nutrition, Inc.

Derived from a purple flower, milk Thistle helps maintain healthy liver functions. Milk Thistle contains antioxidant properties that help fight free radicals in the body. Free radicals may contribute to the premature aging of cells. Spring Valleys Milk Thistle is standardized for 80% Silymarin. This means that you can be assured of receiving a consistent level of active ingredients with each serving.

Nature's Bounty Milk Thistle, 175 mg, Standardized Extract, 50 Capsules (Pack of 2)

Nature's Bounty Milk Thistle, 175 mg, Standardized Extract, 50 Capsules (Pack of 2)
by Nature's Bounty

Herbal Supplement. Promotes Healthy Liver Function. Derived from a purple flower, Milk Thistle helps maintain healthy liver function. Milk Thistle may protect the cells of the liver by blocking the entrance of harmful toxins and helping remove these toxin

Amermed Milk Thistle 1950mg 80% Silymarin, 90 capsules

Amermed Milk Thistle 1950mg 80% Silymarin, 90 capsules
by Amermedp



21st Century Standardized Herbal Extract Capsules, Milk Thistle Extract, Maximum Strength, 200-Count Bottles (Pack of 2)

21st Century Standardized Herbal Extract Capsules, Milk Thistle Extract, Maximum Strength, 200-Count Bottles (Pack of 2)
by 21st Century

21st Century's Milk Thistle Extract (Silybum marianum) is grown wild in Europe and America and has been used as a powerful health tonic for over 2000 years. Silymarin, the active complex found in Milk Thistle Extract, is standardized to 80% and is a power

Jarrow Formulations Jarrow Silymarin 150mg, 200 Capsules

Jarrow Formulations Jarrow Silymarin 150mg, 200 Capsules
by Jarrow Formulations

Silymarin is composed of three flavonoids: primarily Silybin and minor amounts of Silydianin and Silychristin, which support liver function by raising protective glutathione levels.



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