 |
|
A study undertaken at the University of Navarra relates the neural damage provoked by Ecstasy with the ambient temperature at which it is consumed
August 06, 2007There exists a direct relationship between the consumption of MDMA, or Ecstasy, at a high ambient temperature and an increase in the neural damage which this drug provokes. This was the conclusion of the research carried out by Beatriz Goñi at the School of Pharmacy of the University of Navarra.
These results form part of her doctoral dissertation, entitled "A Study of the Neurotoxicity Mechanism of 3.4-methylenedioxy-N-methylamphetamine (MDMA or 'Ecstasy') after its Administration in Rats: New Responses to Old Questions." By means of this study, the researcher was able to relate for the first time the body temperature of the user with a higher metabolism of this substance. There are two factors which, when they co-occurcan produce malignant hyperthermia, a disorder which can sometimes be fatal.
In order to come to this conclusion, the Pamplonan pharmaceutical specialist administered the drug to rats at ambient temperatures of 15, 21 and 30 degrees centigrade. After performing the pertinent analyses, she demonstrated that metabolism of Ecstasy is accelerated by higher ambient temperatures at the time of administration. In addition, higher ambient temperatures also increase, in the same proportion, the neurochemical deficit that affects the brains of the users of this drug.
Higher Risk in Closed Establishments
According to Beatriz Goñi, the author of the study undertaken at the University of Navarra, the discoveries of this research project acquire more relevance precisely because Ecstasy is typically taken in closed environments, with lots of people and poor ventilation, due to which factors the temperature tends to be quite high.
In addition, she notes that the neural damage provoked by this substance, and which originally was only observed in rats, has already been demonstrated in humans, who appear to suffer severe damage to the serotoninergenic neurons, which are involved in processes as basic as sleep, appetite and mood regulation.
Finally, the pharmaceutical specialist noted that the damage caused by the consumption of MDMA is dependent upon its being metabolized after to its ingestion, since if it were administered directly to the brain, neuronal damage would not occur.
Elhuyar Fundazioa
Higher Risk in Closed Establishments
According to Beatriz Goñi, the author of the study undertaken at the University of Navarra, the discoveries of this research project acquire more relevance precisely because Ecstasy is typically taken in closed environments, with lots of people and poor ventilation, due to which factors the temperature tends to be quite high.
In addition, she notes that the neural damage provoked by this substance, and which originally was only observed in rats, has already been demonstrated in humans, who appear to suffer severe damage to the serotoninergenic neurons, which are involved in processes as basic as sleep, appetite and mood regulation.
Finally, the pharmaceutical specialist noted that the damage caused by the consumption of MDMA is dependent upon its being metabolized after to its ingestion, since if it were administered directly to the brain, neuronal damage would not occur.
Elhuyar Fundazioa
Ecstasy Current Events and Ecstasy News RSSYoung people are intentionally taking drink and drugs for better sex
Teenagers and young adults across Europe drink and take drugs as part of deliberate sexual strategies. Findings published today in BioMed Central's open access journal, BMC Public Health, reveal that a third of 16-35 year old males and a quarter of females surveyed are drinking alcohol to increase their chances of sex, while cocaine, ecstasy and cannabis are intentionally used to enhance sexual arousal or prolong sex.
Club drugs inflict damage similar to traumatic brain injury
What do suffering a traumatic brain injury and using club drugs have in common"? University of Florida researchers say both may trigger a similar chemical chain reaction in the brain, leading to cell death, memory loss and potentially irreversible brain damage.
Recreational cocaine use may impair inhibitory control
The recreational use of cocaine has rapidly increased in many European countries over the past few years.
World's smallest radio uses single nanotube to pick up good vibrations
Physicists at the University of California, Berkeley, have built the smallest radio yet - a single carbon nanotube one ten-thousandth the diameter of a human hair that requires only a battery and earphones to tune in to your favorite station.
Breaking up may not be as hard as the song says
The devastation caused by a broken heart has been a dominant theme throughout the ages of great literature and pop culture alike.
Leading toxicologist warns against new drug of abuse
Professor Alison Jones said benzylpiperazine was a "new drug of abuse" which could have serious clinical effects - similar to those of ecstasy to which it is structurally related.
Ecstasy can harm the brains of first-time users
Researchers have discovered that even a small amount of MDMA, better known as ecstasy, can be harmful to the brain, according to the first study to look at the neurotoxic effects of low doses of the recreational drug in new ecstasy users.
Research links 'ecstasy' to survival of key movement-related cells in brain
New research from the University of Cincinnati (UC) suggests that the widely abused club drug "ecstasy," or MDMA, can increase the survival of dopamine cells in the brain during fetal development.
Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience
Using unusually rigorous scientific conditions and measures, Johns Hopkins researchers have shown that the active agent in "sacred mushrooms" can induce mystical/spiritual experiences descriptively identical to spontaneous ones people have reported for centuries.
New mechanism found for neurodegenerative effects of amphetamines in mice
University of Toronto researchers have discovered a new mechanism for the neurodegenerative effects of amphetamines.
More Ecstasy Current Events and Ecstasy News Articles
 | The Agony and the Ecstasy: A Biographical Novel of Michelangelo by Irving Stone Celebrating the 500th anniversary of Michelangelo's David, New American Library releases a special edition of Irving Stone's classic biographical novel-in which both the artist and the man are brought to life in full. A masterpiece in its own right, this novel offers a compelling portrait of Michelangelo's dangerous, impassioned loves, and the God-driven fury from which he wrested the greatest... |
 | After the Ecstasy, the Laundry: How the Heart Grows Wise on the Spiritual Path by Jack Kornfield “Enlightenment does exist,” internationally renowned author and meditation master Jack Kornfield assures us. “Unbounded freedom and joy, oneness with the divine ... these experiences are more common than you know, and not far away.” But even after achieving such realization — after the ecstasy — we are faced with the day-to-day task of translating that freedom into our imperfect... |
 | The Art of Sexual Ecstasy: The Path of Sacred Sexuality for Western Lovers by Margot Anand, M. E. Naslednikov This landmark book on human sexuality makes the sacred lovemaking techniques of the East fully comprehensible to Western readers. Elegantly illustrated, it helps the reader acquire new attitudes and broaden his or her range of experience, to revitalize and strengthen... |
 | Tantra: Path of Ecstasy by Georg Feuerstein Tantra—often associated with Kundalini Yoga—is a fundamental dimension of Hinduism, emphasizing the cultivation of "divine power" (shakti) as a path to infinite bliss. Tantra has been widely misunderstood in the West, however, where its practices are often confused with eroticism and licentious morality. Tantra: The Path of Ecstasy dispels many common misconceptions, providing an accessible... |
 | Ecstasy: The Shadowdwellers by Jacquelyn Frank Among the Shadow dwellers, Trace holds power that some as willing to kill for. Without a stranger's aid, one rival would surely have succeeded, but Trace's brush with death is less surprising to him than his reaction to the beautiful, fragile human who heals him. By rights, Trace should hardly even register Ashla's existence within the realms of Shadow scape, but instead he is drawn to everything... |
 | Music, The Brain, And Ecstasy: How Music Captures Our Imagination by Robert Jourdain What makes a distant oboe's wail beautiful? Why do some kinds of music lift us to ecstasy, but not others? How can music make sense to an ear and brain evolved for detecting the approaching lion or tracking the unsuspecting gazelle? Lyrically interweaving discoveries from science, psychology, music theory, paleontology, and philosophy, Robert Jourdian brilliantly examines why music speaks to us... |
 | Mariette in Ecstasy by Ron Hansen The highly acclaimed and provocatively rendered story of a young postulant's claim to divine possession and religious... |
 | 13: Thirteen Stories That Capture the Agony and Ecstasy of Being Thirteen "If thirteen is supposed to be an unlucky number...you would think a civilized society could come up with a way for us to skip it." -- from "What's the Worst That Could Happen?" by Bruce CovilleNo one will want to skip any of the twelve short stories and one poem that make up this collection by some of the most celebrated contemporary writers of teen fiction. The big bar mitzvah that goes... |
| The Agony and the Ecstasy a Novel of Michelangelo by Irving Stone | |
 | Tantric Secrets for Men: What Every Woman Will Want Her Man to Know about Enhancing Sexual Ecstasy by Kerry Riley Contains everything a man needs to know in order to be a good lover, based on esoteric traditions of sexual ecstasy.• Includes practical and easy-to-follow Tantric rituals and sacred sexuality exercises for a modern lifestyle.• Uses real-life stories of couples to show the benefits achieved with the practices.• Offers an approach to lovemaking that encompasses all dimensions--physical,... |
| © 2008 BrightSurf.com |