 |
|
Study Suggests Estrogen Deficiency Can Lead To Obesity-Induced
August 09, 2007Austin, TX - At menopause, women lose hormone protection against heart (cardiovascular) and kidney (renal) diseases, and are likely to become obese. A research team has tested the idea that estrogen deficiency in aged females may trigger the development of high blood pressure and obesity. The results of their study, using an animal model, suggest that estrogen depletion can have these effects.
The study is entitled, "Role of Estrogens in Postmenopausal Obesity and Hypertension." It was conducted by Lourdes A. Fortepiani and Huimin Zhang, University of Texas Health Science Center at San Antonio (UTHSCSA), San Antonio, TX. The team will discuss its findings as part of the upcoming conference, Sex and Gender in Cardiovascular-Renal Physiology and Pathophysiology, being held August 9-12, 2007 at the Hyatt Regency Austin on Town Lake in Austin, TX. The event is the second scientific gathering to be sponsored by the American Physiological Society (APS; www.The-APS.org) this year.
To test their theory the researchers used 24 aged female rats. The ovaries were removed from two-thirds of the group (ovariectomized; ovx) while the ovaries of the other third of the group remained intact and served as controls. The researchers subdivided the ovx rats, giving half of the ovx group estrogen while the other half remained estrogen depleted.
Among the ovx rats, those that did not receive estrogen had significantly higher blood pressure than the control rats (126.2 versus 110.6 mmHg). The rats receiving estrogen had the lowest blood pressure levels of all (102.6 mmHg).
The researchers also noted that the rats which had their ovaries removed and did not receive estrogen compared to the intact rats
* gained twice as much weight as the controls
* increased their leptin level by 70 percent
* increased their blood glucose level by 35 percent
* increased RAS and renal SNS by 16 and 39 percent
* experienced no change in kidney function
All the hormonal and metabolic effects were completely abolished with estrogen replacement. In other words, the rats whose ovaries were removed and received estrogen replacement did not undergo any of the changes mentioned above.
With increased life expectancy, women spend more than a third of their life in menopause. In addition, obesity is increasing dramatically in all populations and is a major cardiovascular risk factor in women after menopause. Despite the controversial data about estrogen therapy in clinical studies, the results of this study performed in aged rats suggest that the loss of estrogens after menopause may contribute to the development of obesity and hypertension, opening new therapeutic approaches to postmenopausal hypertension.
American Physiological Society
Among the ovx rats, those that did not receive estrogen had significantly higher blood pressure than the control rats (126.2 versus 110.6 mmHg). The rats receiving estrogen had the lowest blood pressure levels of all (102.6 mmHg).
The researchers also noted that the rats which had their ovaries removed and did not receive estrogen compared to the intact rats
* gained twice as much weight as the controls
* increased their leptin level by 70 percent
* increased their blood glucose level by 35 percent
* increased RAS and renal SNS by 16 and 39 percent
* experienced no change in kidney function
All the hormonal and metabolic effects were completely abolished with estrogen replacement. In other words, the rats whose ovaries were removed and received estrogen replacement did not undergo any of the changes mentioned above.
With increased life expectancy, women spend more than a third of their life in menopause. In addition, obesity is increasing dramatically in all populations and is a major cardiovascular risk factor in women after menopause. Despite the controversial data about estrogen therapy in clinical studies, the results of this study performed in aged rats suggest that the loss of estrogens after menopause may contribute to the development of obesity and hypertension, opening new therapeutic approaches to postmenopausal hypertension.
American Physiological Society
Estrogen Current Events and Estrogen News RSSMenopause-cardiology consensus statement on cardiovascular disease and on HRT
A menopause-cardiology consensus statement has called for direct action to prevent cardiovascular disease (CVD) in menopausal women. The statement also concludes that there is little evidence of increased CVD risk in taking HRT.
Heart and bone damage from low vitamin D tied to declines in sex hormones
Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone.
Fertility procedures need not delay breast cancer treatment for younger women
A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion.
Coffee break: Compound brewing new research in colon, breast cancer
A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists.
Mayo researchers find robotic repair for vaginal prolapse has significant benefits
New Mayo Clinic research has found that robotic surgery for vaginal prolapse dramatically reduces patient hospital stay and recovery time.
Estrogen therapy likely must be given soon after menopause to provide stroke protection
For estrogen replacement to provide stroke protection, it likely must be given soon after levels drop because of menopause or surgical removal of the ovaries, scientists report in the Journal of Neuroscience.
Oral contraceptives may benefit women with asthma
New research shows that during natural menstrual cycles, women with asthma who were not taking oral contraceptives (OC) had lower exhaled nitric oxide levels (eNO), a marker of airway inflammation associated with asthma, than women who were taking OC.
Study shows hormone replacement therapy decreases mortality in younger postmenopausal woman
Hormone replacement therapy (HRT) to treat menopausal estrogen deficiency has been in widespread use for over 60 years. Several observational studies over the years showed that HRT use by younger postmenopausal women was associated with a significant reduction in total mortality; available evidence supported the routine use of HRT to increase longevity in postmenopausal women.
Hormone mix could cut breast cancer risk and treat symptoms of menopause
The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk.
Breast tenderness during hormone replacement therapy linked to elevated cancer risk
Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy who didn't experience such tenderness, according to a new UCLA study.
More Estrogen Current Events and Estrogen News Articles
|
Source Naturals Phyto-Estrogen Cream, 4 oz (113.4 g) by Source Naturals Advanced liposomal delivery. Non-GMO soy. Phyto-Estrogen Cream offers some of the finest phytoestregens, renowned for use during menopause. Each ounce contains 60 mg of isoflavone phytoestrogens, along with 150 mg of pomegranate juice extract, and 100 mg of red clover extract. Micro-penetrating liposomes pass through skin layers more easily than non-liposomal creams. | |
 |
Natural Estrogen with Pomegranate Extract, 60 caplets by Life Extension Natural Estrogen with Pomegranate Extract60 caplets Item Catalog Number: 712 In an attempt to provide aging women with the multiple health effects of the bodies’ estrogen without side effects, scientists have discovered plant extracts with estrogenic activity (phytoestrogens). Natural Estrogen with Pomegranate Extract is one answer to the concerns of maintaining healthy hormone function. A review of the published literature reveals some interesting findings about how plant-derived estrogens can provide safe and effective support for such menopausal symptoms as hot flashes. Derived from organically-grown fruit, the pomegranate extract in this formula has the same ratio of polyphenols found in the whole fruit and all the benefits one would get from the juice without the sugar, calories,... |
 |
Estrogen/Estriol (Bio-Identical) Fragrance Free Cream 2 oz. Pump Bottle by Radiant Laboratories - Made In USA Paraben-Free and Unscented. Menopausal Hot Flashes? Night Sweats? Trouble Sleeping? Replenish Your Estrogen Naturally and Safely. Get your life back! Estriol Has Been Used in Europe for Years. Bio-identical Hormones Are Safe and Effective. Non Prescription Bio-identical Natural Estrogen (Estriol Usp) Not to Be Confused with Phyto-estrogens. Bio-identical Hormones Are Safe for Women Help Relieve Menopause Symptoms. Estriol is not a phyto estrogen. Don't confuse phyto estrogens with pure natural estriol USP. The natural estrogen, estriol USP, is made the same way natural progesterone USP is made. Sterol analogues found in many varieties of plants are combined with specific bacteria and the resulting hormone is bio identical in chemical structure to the hormone produced by the human body.... |
 |
Emerita Phytoestrogen Body Cream with Black Cohosh, 2-Ounce Tube by Emerita Peri/Menopause support. Paraben-free. Who knew a little tube of cream could change the world? In 1978 we had a revolutionary idea: that there was not enough real choice when it came to peri / menopause. So we created Pro-Gest, Phytoestrogen Cream and Pers |
 |
Estrogen Revisited: Lifelong & Fearless by Donna Walters (Author) Estrogen is essential for good health and well being in women of all ages throughout their lives. I have written this book because I want to encourage women who have been on hormone replacement, like me, to consider remaining on it for life as I plan to do. For women who have been scared or hesitant to take estrogen because they are afraid of contracting breast cancer as predicted by the incorrect conclusions of the Women's Health Initiative in 2002, read this book and save your life. My doctor told me that I should stop taking estrogen because it is recommended for the shortest amount of time to control symptoms only. I have researched this issue for over a year because I want to make the right decision for me. I have decided to share my findings and experience of long term estrogen use... |
 |
Phyto-Estrogen 60 Capsules by Gaia Herbs Provides a Natural Hormonal Balance During the Onset of Menopause Rich Natural Source of Phytoestrogens Support for the Peri-Menopause and Menopausal Years |
 |
Estroven Maximum Strength - 98 Caplets by Amerifit Estroven Maximum Strength is clinically shown to reduce hot flashes and night sweats. It contains a higher level of the key black cohosh and soy isoflavones ingredients found in Estroven Regular Strength, plus additional vitamins and minerals for women's health. |
 |
Alternative Health & Herbs Remedies Female Estrogen W, progesterone, 1-Ounce Bottle by Alternative Health & Herbs Remedies Alternative Health & Herbs Remedies Female Estrogen W, progesterone, promotes hormonal balance, effective for women who are experiencing menopause and it does not contain hormones. |
 |
TestroPlex - 90 Capsules Anti-Estrogen & Anti-Aromatase Complex Testosterone Booster Tribulus Chrysin by Bionutricals The amount of free testosterone can be altered (increased) by the use of aromatase inhibitors such as TestroPlexTM. The less testosterone that is synthesized [aromatized] into estrogen, the more total testosterone) or inhibitors of the plasma proteins that bind into testosterone. Manipulating the tendency of a testosterone to exist in an unbound state is an effective way to alter the overall activity and potency of ones overall testosterone levels. Higher levels of testosterone produce an enhanced anti-glucocorticoid effect, which yields an anti-catabolic, or more precisely, anti-proteoolytic, effect on muscle cells. This indirect effect is the result of testosterones high affinity for binding with glucocorticoid receptors, thus blocking the normal messenger pathway that triggers protein... |
 |
The Greatest Experiment Ever Performed on Women: Exploding the Estrogen Myth, Second Edition by Barbara Seaman (Author) A Library Journal Best Consumer Health Book of 2003 and an American Library Association/Booklist Editor's Choice Book of 2003 "Barbara Seaman is the first prophet of the women's health movement and her prophecies are still coming true."-Gloria Steinem "A wake-up call to women about unquestioningly accepting doctors' orders."-Booklist (starred review) "Lively and impassioned . . . [Seaman] certainly makes her point."-Gina Kolata, The New York Times With the ardent tone of a close friend, Barbara Seaman draws on forty years of journalistic research to expose the "menopause industry" and shows how estrogen therapy often causes more problems-including breast cancer, heart attack, and stroke-than it cures. The Greatest Experiment Ever Performed on Women tracks the... |
| © 2009 BrightSurf.com |