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Immune deficiency linked to a type of eye cancer
August 15, 2007The incidence of squamous cell eye cancer is greater among kidney transplant patients and people with human immunodeficiency virus (HIV) than the general public, which suggests the disease is associated with immune deficiency.
Claire Vajdic, Ph.D., of the University of New South Wales in Sydney and colleagues compared the incidence of squamous cell eye cancer in the general population with that of kidney transplant patients, who have suppressed immune systems.
Of the 10,180 patients in the study, five were diagnosed with this eye cancer; less than one case was expected. Residence in the subtropical state of Queensland and prior history of squamous cell skin cancer were associated with higher risk of squamous cell eye cancer.
"The carcinogenic mechanism is not known, but the available evidence suggests an effect of solar ultraviolet radiation and possibly HPV infection," the authors write.
Journal of the National Cancer Institute
"The carcinogenic mechanism is not known, but the available evidence suggests an effect of solar ultraviolet radiation and possibly HPV infection," the authors write.
Journal of the National Cancer Institute
Eye Cancer News and Current Eye Cancer Events RSSSt. Jude defines eye cancer gene's role in retinal development
A genetic discovery led by scientists at St. Jude Children's Research Hospital helps answer a long-standing mystery about the eyes of vertebrates, and may translate into a deeper understanding of how genes coordinate the complex process of eye formation and how a rare pediatric eye cancer progresses.
St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory
Investigators at St. Jude Children's Research Hospital have identified the cell that gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development.
New genetic test predicts risk of metastasis in patients with deadly eye cancer
Imagine being diagnosed with eye cancer - but your doctor can't tell whether you have the aggressive type that will swiftly spread, causing blindness and death in as early as a year.
St. Jude announces breakthrough in eye cancer treatment
Scientists at St. Jude Children's Research Hospital have demonstrated in a mouse model a new, locally applied treatment for the eye cancer retinoblastoma that not only greatly reduces the size of the tumor, but does so without causing the side effects common with standard chemotherapy.
Genetic insights may explain retinal growth, eye cancer
Investigators at St. Jude Children's Research Hospital have discovered the role of several key genes in the development of the retina, and in the process have taken a significant step toward understanding how to prevent or cure the potentially deadly eye cancer retinoblastoma.
Radiation therapy can help spare vision in patients with melanoma of the eye
Treating a rare form of eye cancer with radiation therapy can spare patients from significant vision loss.
Retinoblastoma researchers find success with two-drug combination
Retinoblastoma is a tumor that arises in the cells of the retina, the light-sensitive tissue at the back of the eyeball, following mutation of the gene RB1.
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