Umbilical cord clamping should be delayed, says expertAugust 17, 2007Editorial: Umbilical cord clamping after birth Clamping and cutting of the umbilical cord should be delayed for three minutes after birth, particularly for pre-term infants, suggests a senior doctor in this week's BMJ. Early clamping and cutting of the umbilical cord is widely practised as part of the management of labour, but recent studies suggest that it may be harmful to the baby. The rate of early cord clamping varies widely in Europe, from 17% of units in Denmark to 90% in France. So Dr Andrew Weeks, a senior lecturer in obstetrics at the University of Liverpool, looked at the evidence behind cord clamping. For the mother, trials show that early cord clamping has no ill effects, he writes. But what about the baby" At birth, he says, the umbilical cord sends oxygen-rich blood to the lungs until breathing establishes. So as long as the cord is unclamped, the average transfusion to the newborn is equivalent to 21% of the neonate's final blood volume and three quarters of the transfusion occurs in the first minute after birth. For babies born at term, the main effect of this large autotransfusion is to increase their iron status. This may be lifesaving in areas where anaemia is endemic. In the developed world, however, there have been concerns that it could increase the risk of polycythaemia and hyperbilirubinaemia (abnormally high levels of red blood cells and bile pigments in the bloodstream, often leading to jaundice). But trials show this is not the case. For pre-term babies the beneficial effects of delayed clamping may be greater, he says. Although the studies are smaller, delayed clamping is consistently associated with reductions in anaemia, bleeding in the brain (intraventricular haemorrhage), and the need for transfusion. So how should we approach cord clamping in practice, he asks" In normal deliveries, delaying cord clamping for three minutes with the baby on the mother's abdomen should not be too difficult. The situation is a little more complex for babies born by caesarean section or for those who need support soon after birth. Nevertheless, it is these babies who may benefit most from a delay in cord clamping. For them, a policy of 'wait a minute' would be pragmatic, he says. There is now considerable evidence that early cord clamping does not benefit mothers or babies and may even be harmful, he writes. Both the World Health Organisation and the International Federation of Gynecology and Obstetrics (FIGO) have dropped the practice from their guidelines. It is time for others to follow their lead and find practical ways of incorporating delayed cord clamping into delivery routines, he concludes. BMJ-British Medical Journal |
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| Related Umbilical Cord Current Events and Umbilical Cord News Articles U of M researchers find 2 units of umbilical cord blood reduce risk of leukemia recurrence A new study from the Masonic Cancer Center, University of Minnesota shows that patients who have acute leukemia and are transplanted with two units of umbilical cord blood (UCB) have significantly reduced risk of the disease returning. The use of stem cells in regenerative medicine may also be detrimental for health The use of stem cells in regenerative medicine is not always beneficial for human health, it may even be harmful according to a work done by the University of Granada and University of León. Scientists have demonstrated that transplantation of human mononuclear cells isolated from umbilical cord blood exerted a deleterious effect in rats with liver cirrhosis. NIH launches 2009 H1N1 influenza vaccine trials in HIV-infected pregnant women The first clinical trials to test whether the 2009 H1N1 influenza vaccine can safely elicit a protective immune response in pregnant women launched yesterday, and a trial to conduct the same test in HIV-infected children and youth will begin next week. Major improvements made in engineering heart repair patches from stem cells University of Washington (UW) researchers have succeeded in engineering human tissue patches free of some problems that have stymied stem-cell repair for damaged hearts. Private umbilical cord banking not cost-effective, UCSF research shows Private cord blood banking is not cost-effective because it costs an additional $1,374,246 per life-year gained, according to a new analysis by UCSF researchers. Stem cell research: From molecular physiology to therapeutic applications Stem cell research promises remedies to many devastating diseases that are currently incurable, ranging from diabetes and Parkinson's disease to paralysis. Experimental treatment halts hypoxic-ischemic brain injury in newborns Inhibiting an enzyme in the brains of newborns suffering from oxygen and blood flow deprivation stops a type of brain damage that is a leading cause of cerebral palsy, mental retardation and death, according to researchers at Cincinnati Children's Hospital Medical Center. Children's Hospital Oakland scientists first to discover new source for harvesting stem cells A groundbreaking study conducted by Children's Hospital & Research Center Oakland is the first to reveal a new avenue for harvesting stem cells from a woman's placenta, or more specifically the discarded placentas of healthy newborns. MIT: New system monitors fetal heartbeat Tiny fluctuations in a fetus's heartbeat can indicate distress, but currently there is no way to detect such subtle variations except during labor, when it could be too late to prevent serious or even fatal complications. Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma If you're one of the millions who dread the spring allergy season, things are looking up. More Umbilical Cord Current Events and Umbilical Cord News Articles |
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