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Many parents at-risk for cancer disclose genetic test results to children
August 20, 2007Predictive genetic testing for adult-onset diseases, including cancer, is generally discouraged until the age at which interventions are believed to be helpful. Yet, many children of BRCA mutation carriers learn of their parents' genetic test results many years before preventive interventions are indicated.
A new study in the Aug. 20 Journal of Clinical Oncology, describes the prevalence and experiences of parental communication of BRCA results to children under the age of 25 years old.
"More than half of the parents told their children about their genetic test results. Some parents reported that their children didn't seem to understand the significance of the information shared, and that some had initial negative reactions. Further research is needed to understand the impact of this communication on these children in order to provide optimal counseling for families with a genetic risk of cancer" said the study's author, Angela Bradbury, M.D., director of Fox Chase Cancer Center's Family Risk Assessment Program.
Fox Chase Cancer Center
Fox Chase Cancer Center
Cancer News and Current Cancer Events RSSNew insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors.
Researchers discover how rheumatoid arthritis causes bone loss
Researchers have discovered key details of how rheumatoid arthritis (RA) destroys bone, according to a study published in the Aug. 22 edition of the Journal of Biological Chemistry.
Making 'good' fat from muscle and vice versa
A surprise discovery -- that calorie-burning brown fat can be produced experimentally from muscle precursor cells in mice -- raises the prospect of new ways to fight obesity and overweight, say scientists from Dana-Farber Cancer Institute.
Researchers discover scent of skin cancer
According to new research from the Monell Center, odors from skin can be used to identify basal cell carcinoma, the most common form of skin cancer. The findings, presented at the 236th meeting of the American Chemical Society, may open doors to development of new methods to detect basal cell carcinoma and other forms of skin cancer.
Cervical cancer prevention should focus on vaccinating adolescent girls
The cost-effectiveness of vaccination in the United States against human papillomavirus (HPV), a sexually-transmitted virus that causes cervical cancer, will be optimized by achieving universal vaccine coverage in young adolescent girls, by targeting initial "catch-up" efforts to vaccinate women younger than 21 years of age, and by revising current screening policies.
Obesity raises risks of serious digestive health concerns
The prevalence of obesity and overweight in the United States coupled by the increased risk of gastrointestinal diseases related to obesity raises serious implications for the health of Americans.
Bowel cancer indicator should lead to better treatment
STEM cell scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should eventually lead to better treatment and survival rates.
Stem cell indicator for bowel cancer should lead to better survival rates
Stem cell scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should eventually lead to better treatment and survival rates. Bowel cancer is the third most common cancer in the UK.
Infection Blocks Lung's Protective Response Against Tobacco Smoke
An infection that often goes undetected can block the lung's natural protective response against tobacco smoke, according to researchers at National Jewish Health.
NYU scientists identify critical protein complex in formation of cell cilia
An international team led by NYU Cancer Institute have identified a protein complex that regulates the formation of cilia, which are found on virtually all mature human cells and are essential to normal cell function.
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