Inhaling helps heal liver transplant recipientsAugust 24, 2007A new report from a team of researchers at the University of Washington, Seattle, and the University of Alabama at Birmingham indicates that one of the main complications of liver transplantation can be treated very simply by allowing the transplant recipients to inhale nitric oxide (NO) during the operation in which they received their new liver. Inhalation of NO decreased the length of time the patients had to stay in hospital and increased the rate at which the function of the transplanted liver was restored, leading the authors to suggest that inhalation of NO is a valuable preemptive approach to enhancing liver function after transplantation. The authors chose to investigate the potential benefits of NO inhalation to liver transplant recipients because ischemia/reperfusion damage, which is one of the main causes of liver dysfunction and failure after transplantation, is associated with decreased NO production by the liver. The study was prospective, blinded, and placebo-controlled and clearly showed that inhaling NO was beneficial to the transplant recipients. Further analysis indicated that the beneficial effects of inhaled NO were probably mediated through increased levels of nitrite in the circulation. Although these results are extremely promising, the authors caution that further studies using a larger number of patients are needed before a final conclusion about the benefits of inhaling NO can be reached. Journal of Clinical Investigation |
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| Related Transplant Recipients Current Events and Transplant Recipients News Articles Immune therapy can protect against or treat later lymphoma Specially developed immune system cells that target the common Epstein-Barr virus can protect immune-suppressed bone marrow transplant recipients against lymph system disease and cancers that arise from the viral infection. Switching immunosuppressants reduces cancer risk in kidney Switching to a newer type of immunosuppressant drug may reduce the high rate of skin cancer after kidney transplantation, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. Kidney transplants generally safe for lupus patients Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. Important new novel 2009 H1N1 flu advisory for cardiopulmonary transplantation Each year 3-5 million people have severe cases and 250-500,000 die from complications of seasonal influenza world-wide. This year, the novel 2009 H1N1 (nH1N1) influenza, previously called swine flu, has reached pandemic status. Multivisceral transplant survival rates improve with new treatment, says Pittsburgh study Data from the largest single-center experience of adult and pediatric intestinal and multivisceral transplantation show that survival rates have improved with the advent of innovative surgical techniques, novel immunosuppressive protocols and better post-operative management. Prompt diagnosis of ear infections can improve outcome for organ transplant recipients Organ transplant recipients benefit significantly when they are monitored and receive prompt diagnosis and treatment for otitis media, a common inner ear infection. Mars and Venus: Short- and long-term success of male to female kidney transplants Female recipients of kidneys from deceased male donors demonstrate an increased risk of allograft failure in the first year after transplant, but show no increased risk after ten years. Heart transplant recipients can improve fitness and perform high intensity workouts Heart transplant recipients' cardio-respiratory fitness is around 30 to 50 per cent lower than age-matched healthy sedentary individuals. Older kidney transplant patients should more often consider live donors Almost half of kidney transplant candidates older than 60 who are put on the waiting list for a deceased-donor organ will die before getting a transplant. Transplant drug stimulates immune memory Rapamycin, a drug given to transplant recipients to suppress their immune systems, has a paradoxical effect on cells responsible for immune memory, scientists at the Emory Vaccine Center have discovered. More Transplant Recipients Current Events and Transplant Recipients News Articles |
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