Cervical cancer screening: Too many are left unprotectedSeptember 20, 2007The decline in cervical cancer is a success story of cancer research. Although there are reasons to be optimistic about even further decreases in cervical cancer incidence, there still remain some women who are not screened. A meta-analysis by Spence and colleagues published in the August-September 2007 issue of Preventive Medicine shows that undergoing Pap smears irregularly or never was the primary explanation for the development of invasive cervical cancer, followed by false negative tests and poor follow-up of abnormal results. Papanicolaou and Traut first reported the usefulness of the Papanicolaou smear (''Pap test") for detecting neoplastic cervical cells in 1943. A smear of cells of the uterine cervix indicating the progression of the cancer's growing malignity provided a powerful screening tool that became rapidly used after WWII without its efficacy being evaluated in a randomized control trial. In the United States, the Pap test is credited with having halved the annual cervical cancer incidence rate (from 17.2 to 8.0 per 100,000) and mortality rate (from 6.2 to 2.9) from 1973 to 1999. In 2000, 83% of U.S. women age 18 and older who had not had a hysterectomy reported having had a Pap test within the past 3 years. The recent discovery of a vaccine against human papillomavirus (HPV), the main cause of cervical cancer, opens the way to the primary prevention of the disease. The natural history of cervical cancer progression combined with the availability of an HPV vaccine and an effective screening test indicate that eradication of the disease is a plausible objective. To reach that goal, however, it is important not to give up on the minority of women who do not fully benefit from available prevention methods and unfortunately fail to be reached by health promotion messages. Dr. Eduardo Franco, the study's principal investigator, commented on the findings: "Cervical cancer is a sentinel disease of inequity. The socio-economic disparity already seen with availability of screening could aggravate if vaccination fails to reach the daughters of women at greatest risk. Like mothers, like daughters; the latter unvaccinated and unprotected by screening will eventually contribute to the sad reality of cervical cancer statistics in the future. The solution is to adopt vaccination and screening as universal strategies, with the latter modified to make cost-effective use of limited resources." Elsevier |
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| Related Cervical Cancer Current Events and Cervical Cancer News Articles 1 disease, not 1 demographic The Asian continent has nearly four billion people living in 47 different countries, and each of these groups has their own unique set of health issues. But when they come to the United States, they're often lumped into one large demographic: "Asian/Pacific Islander." Alternatively spliced tissue factor identified as promising new biomarker for aggressive cancers A recently discovered form of the protein that triggers blood clotting may play a key role in the molecular mechanisms leading to the growth of certain metastatic cancers, according to new research reported by an international team of scientists. M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers. Study finds delay in follow-up among African-American women receiving abnormal breast finding A new analysis has identified a significant delay in follow-up times among African-American women after the finding of a suspicious breast abnormality. UIC study finds girls aware of HPV vaccine's benefits Contrary to concerns that the human papillomavirus vaccine might promote promiscuity, a national survey of girls and young women found that the majority of respondents did not believe the HPV vaccine protected them against other sexually transmitted infections. Scientists identify common HPV genotypes in northern India, encourage vaccination Although a wide spectrum of human papillomavirus is seen across the population of India, HPV-16 and HPV-18 are the most common types and a vaccination targeting these types could eliminate 75 percent of the cervical cancers in the region. Vaccinating boys against human papillomavirus not cost-effective Persistent infection with high-risk types of human papillomavirus (HPV), a sexually transmitted virus, is known to be a cause of cervical cancer. Vaccination and testing for the human papilloma virus could eradicate cervical cancer Cervical cancer could be eradicated within the next 50 years if countries implement national screening programmes based on detection of the human papilloma virus (HPV), which causes the disease, together with vaccination programmes against the virus, according to a cervical cancer screening expert. Targeted heat therapy offers new standard treatment option for soft tissue sarcoma Patients with soft-tissue sarcomas at high risk of spreading were 30% more likely to be alive and cancer free almost three years after starting treatment if their tumours were heated at the time they received chemotherapy, according to new research. Even in a safety net health system, colorectal cancer screening disparities remain Colorectal cancer screening rates are much lower among those in a safety net health system compared to the national average, and the number one predictor of screening is a combination of regular visits and insurance access. More Cervical Cancer Current Events and Cervical Cancer News Articles |
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