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Medimmune announces phase 2 safety data for anti-RSV antibody and national RSV surveillance results
October 05, 2007MedImmune, Inc. today announced results from two important studies presented at the 2007 Infectious Diseases Society of America (IDSA) 45th Annual Meeting adding to the body of knowledge about respiratory syncytial virus (RSV). RSV is a viral pathogen that produces annual outbreaks usually between fall and spring. While RSV typically manifests cold-like symptoms in healthy children, it can prove to be a very serious respiratory illness for premature infants and is the leading cause of respiratory infections for newborns each year. MedImmune has long been committed to developing and improving products for prevention of RSV disease and to enhancing the body of knowledge about RSV epidemiology.
"MedImmune continues to forge ahead with its aggressive strategy to help combat RSV disease," said Edward M. Connor, M.D., executive vice president and chief medical officer. "We are pleased to present new Phase 2 data at IDSA regarding motavizumab, a key investigational monoclonal antibody (MAb) within our product development portfolio that we are currently preparing for regulatory submission in the United States."
Connor added, "We will also present data regarding RSV surveillance at IDSA. These data show regional variability of RSV in the community, particularly in the southernmost United States. We believe that a better understanding of the regional variation in the timing of RSV may help inform decisions about timing of RSV prophylaxis for children at risk for serious RSV disease."
Data pertaining to MedImmune's anti-RSV initiatives that will be presented during the IDSA meeting include:
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Safety, Tolerability, and Immunogenicity of Motavizumab in Young Children After a Second Season of RSV Prophylaxis (Poster Presentation #233) - Katia G. Abarca, M.D., Infectious Diseases and Molecular Virology Laboratory, Universidad Católica de Chile, Friday, October 5, 2007; 12:30 - 2:00 p.m. in Poster Halls G-H.
This study assessed the safety and immunogenicity of motavizumab, an investigational anti-RSV MAb, in young children with a history of prematurity who received two sequential seasons of the antibody.
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RSV Surveillance: Retrospective and Current Data on the Variance in Season Onsets and Offsets (Poster Presentation #719) - Jessie R. Groothuis M.D., MedImmune, Saturday, October 6, 2007; 12:15 - 1:45 p.m. in Poster Halls G-H.
A nationwide active surveillance program was established to evaluate the variability of the RSV season temporally and geographically in the United States. Laboratory results from a three-year period were analyzed by month and by geographic region.
Edelman Public Relations
Data pertaining to MedImmune's anti-RSV initiatives that will be presented during the IDSA meeting include:
*
Safety, Tolerability, and Immunogenicity of Motavizumab in Young Children After a Second Season of RSV Prophylaxis (Poster Presentation #233) - Katia G. Abarca, M.D., Infectious Diseases and Molecular Virology Laboratory, Universidad Católica de Chile, Friday, October 5, 2007; 12:30 - 2:00 p.m. in Poster Halls G-H.
This study assessed the safety and immunogenicity of motavizumab, an investigational anti-RSV MAb, in young children with a history of prematurity who received two sequential seasons of the antibody.
*
RSV Surveillance: Retrospective and Current Data on the Variance in Season Onsets and Offsets (Poster Presentation #719) - Jessie R. Groothuis M.D., MedImmune, Saturday, October 6, 2007; 12:15 - 1:45 p.m. in Poster Halls G-H.
A nationwide active surveillance program was established to evaluate the variability of the RSV season temporally and geographically in the United States. Laboratory results from a three-year period were analyzed by month and by geographic region.
Edelman Public Relations
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Infectious Disease Current Events and Infectious Disease News RSSMeasurements fail to identify TB patients who could benefit from shorter treatment course
Tuberculosis (TB) is a difficult infection to treat and requires six months of multiple antibiotics to cure it. To combat the TB pandemic, a shorter and simpler drug treatment would be a huge advance since most TB occurs in resource-limited settings with poor public health infrastructures.
Scientific system accurately predicts spread of H1N1: study
A new scientific system developed by a St. Michael's Hospital physician, designed to rapidly evaluate the world's air traffic patterns, accurately predicted how the H1N1 virus would spread around the world.
Study shows Chronix technology using serum DNA can identify early presence of disease
Chronix Biomedical today reported that a new study in a peer-reviewed journal further confirms the potential diagnostic and prognostic utility of using circulating fragments of DNA to detect early stage disease.
Preventing spread of infectious diseases is everyone's responsibility
According to a report published today, we must all share responsibility for preventing the spread of diseases such as swine flu, SARS, avian influenza, diarrhoeal and skin diseases, and even the common cold.
Researchers develop the first climate-based model to predict Dengue fever outbreaks
Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are the most important vector-borne viral diseases in the World.
New arenavirus discovered as cause of hemorrhagic fever outbreak in South Africa and Zambia
Scientists at Columbia University's Mailman School of Public Health, the South African National Institute for Communicable Diseases of National Health Laboratory Service (NICD-NHLS), the U.S. Centers for Disease Control and Prevention, and Roche's 454 Life Sciences Corporation have discovered the new virus responsible for a highly fatal hemorrhagic fever outbreak in Zambia and South Africa in late 2008.
New infectious diseases - what's the risk?
With the current outbreak of swine flu, and in the absence of a vaccine or treatment at present, the only way to contain the virus is to get people around the world to take precautionary measures.
Influenza pandemic planning needed to assure adequate care for pregnant women and newborns
Pregnant women and newborns are at greatest risk in a flu epidemic, but more planning must be done to ensure that they receive priority treatment should an outbreak occur, according to a University of Pittsburgh Medical Center (UPMC) and University of Pittsburgh study.
Visualizing virus replication in 3 dimensions
Dengue fever is the most common infectious disease transmitted by mosquitoes - some 100 million people around the world are infected. Researchers at the Hygiene Institute at Heidelberg University Hospital were the first to present a three-dimensional model of the location in the human cell where the virus is reproduced.
NOAA, USFWS study finds potential disease threats to Washington sea otters
Many of Washington State's sea otters are exposed to the same pathogens responsible for causing disease in marine mammal populations in other parts of the country.
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![Historic Print (L): [The ward for infectious diseases in the Hasköy Hospital for Women] / Constantinopl](http://ecx.images-amazon.com/images/I/51HBG2spnXL._SL160_.jpg) |
Historic Print (L): [The ward for infectious diseases in the Hasköy Hospital for Women] / Constantinopl by Library Images This is a museum quality, reproduction print on premium paper with archival/UV resistant inks. Date: [between 1880 and 1893] Subject: Notes: Title translated from album caption. Captioned in Ottoman Turkish and French. No. 9. No. 545. In album: Hasköy Hospital for Women, fountains, mausoleums, and other buildings and views, Istanbul, Ottoman Empire. Forms part of: Abdul-Hamid II Collection (Library of Congress). Format: Albumen prints 1880-1900. SOURCE: Library of Congress |
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