 |
|
Medimmune announces phase 2 safety data for anti-RSV antibody and national RSV surveillance results
October 05, 2007MedImmune, Inc. today announced results from two important studies presented at the 2007 Infectious Diseases Society of America (IDSA) 45th Annual Meeting adding to the body of knowledge about respiratory syncytial virus (RSV). RSV is a viral pathogen that produces annual outbreaks usually between fall and spring. While RSV typically manifests cold-like symptoms in healthy children, it can prove to be a very serious respiratory illness for premature infants and is the leading cause of respiratory infections for newborns each year. MedImmune has long been committed to developing and improving products for prevention of RSV disease and to enhancing the body of knowledge about RSV epidemiology.
"MedImmune continues to forge ahead with its aggressive strategy to help combat RSV disease," said Edward M. Connor, M.D., executive vice president and chief medical officer. "We are pleased to present new Phase 2 data at IDSA regarding motavizumab, a key investigational monoclonal antibody (MAb) within our product development portfolio that we are currently preparing for regulatory submission in the United States."
Connor added, "We will also present data regarding RSV surveillance at IDSA. These data show regional variability of RSV in the community, particularly in the southernmost United States. We believe that a better understanding of the regional variation in the timing of RSV may help inform decisions about timing of RSV prophylaxis for children at risk for serious RSV disease."
Data pertaining to MedImmune's anti-RSV initiatives that will be presented during the IDSA meeting include:
*
Safety, Tolerability, and Immunogenicity of Motavizumab in Young Children After a Second Season of RSV Prophylaxis (Poster Presentation #233) - Katia G. Abarca, M.D., Infectious Diseases and Molecular Virology Laboratory, Universidad Católica de Chile, Friday, October 5, 2007; 12:30 - 2:00 p.m. in Poster Halls G-H.
This study assessed the safety and immunogenicity of motavizumab, an investigational anti-RSV MAb, in young children with a history of prematurity who received two sequential seasons of the antibody.
*
RSV Surveillance: Retrospective and Current Data on the Variance in Season Onsets and Offsets (Poster Presentation #719) - Jessie R. Groothuis M.D., MedImmune, Saturday, October 6, 2007; 12:15 - 1:45 p.m. in Poster Halls G-H.
A nationwide active surveillance program was established to evaluate the variability of the RSV season temporally and geographically in the United States. Laboratory results from a three-year period were analyzed by month and by geographic region.
Edelman Public Relations
Data pertaining to MedImmune's anti-RSV initiatives that will be presented during the IDSA meeting include:
*
Safety, Tolerability, and Immunogenicity of Motavizumab in Young Children After a Second Season of RSV Prophylaxis (Poster Presentation #233) - Katia G. Abarca, M.D., Infectious Diseases and Molecular Virology Laboratory, Universidad Católica de Chile, Friday, October 5, 2007; 12:30 - 2:00 p.m. in Poster Halls G-H.
This study assessed the safety and immunogenicity of motavizumab, an investigational anti-RSV MAb, in young children with a history of prematurity who received two sequential seasons of the antibody.
*
RSV Surveillance: Retrospective and Current Data on the Variance in Season Onsets and Offsets (Poster Presentation #719) - Jessie R. Groothuis M.D., MedImmune, Saturday, October 6, 2007; 12:15 - 1:45 p.m. in Poster Halls G-H.
A nationwide active surveillance program was established to evaluate the variability of the RSV season temporally and geographically in the United States. Laboratory results from a three-year period were analyzed by month and by geographic region.
Edelman Public Relations
Infectious Disease Current Events and Infectious Disease News RSSGlobal warming link to amphibian declines in doubt
Evidence that global warming is causing the worldwide declines of amphibians may not be as conclusive as previously thought, according to biologists. The findings, which contradict two widely held views, could help reveal what is killing the frogs and toads and aid in their conservation.
Purdue researcher invents molecule that stops SARS
A Purdue University researcher has created a compound that prevents replication of the virus that causes SARS and could lead to a treatment for the disease.
Penn Scientists Show How Body Determines Optimal Amount of Germ-Fighting B Cells
Researchers at the University of Pennsylvania School of Medicine can now explain how the body determines whether there are enough mature B-cells in the blood stream at any one time. These are the cells that produce antibodies against germs to fight infections.
Tibotec presents interim findings for TMC435, an investigational genotype 1 hepatitis C treatment
New clinical data show antiviral activity of TMC435, an investigational protease inhibitor (PI) being developed by Tibotec BVBA for the treatment of chronic hepatitis C virus (HCV) infection.
New molecules with many branches will help unleash potential of nanotechnology
Materials science and the pharmaceutical industry could soon be revolutionized by emerging nanotechnologies based on designer molecules with long complex tree-and branch structures.
Rapid HIV testing in the ER boosts diagnoses, screening
One in every 50 people screened for a suspected sexually transmitted infection (STI) in the Emergency Department at Henry Ford Hospital was found to be infected with HIV using a rapid blood sample screening test.
Vaccinating family members offers important flu protection to newborns
Vaccinating new mothers and other family members against influenza before their newborns leave the hospital creates a "cocooning effect" that may shelter unprotected children from the flu, a virus that can be life-threatening to infants, according to researchers at Duke Children's Hospital.
Avian flu threat: New approach needed
As the first globally co-ordinated plan for the planet's gravest health threats is hatched by government ministers from around the world this weekend, a new report sets out a 10-point plan for this new, globalised approach to infectious diseases such as avian flu.
X marks the spot: Sharpies get thumbs-up for marking surgery sites
A bit of good news out of the Faculty of Medicine & Dentistry at the University of Alberta for patients undergoing surgery or an invasive procedure, their surgeons and cost-conscious hospital administrators.
RNA molecules, delivery system improve vaccine responses, effectiveness
A novel delivery system that could lead to more efficient and more disease-specific vaccines against infectious diseases has been developed by biomedical engineers at The University of Texas at Austin.
More Infectious Disease Current Events and Infectious Disease News Articles
 | Infectious Disease Epidemiology: Theory And Practice by Kenrad E., M.D. Nelson, Carolyn F. Masters, Ph.D. Williams This comprehensive resource applies the fundamentals of epidemiology to the study of infectious diseases (ID). In the first section, readers will learn about basic epidemiologic methods for the study of ID plus be introduced to newer techniques like geographical information systems, mathematical modeling, and genetic laboratory tools. In the second section, the book covers major infectious... |
 | Infectious Diseases of the Dog and Cat , Revised Reprint (Infectious Diseases of the Dog and Cat) by Craig E. Greene Featuring full-color illustrations and hundreds of tables with diagnostic and therapeutic guidelines, this authoritative resource explores the diagnosis and treatment of canine and feline infectious diseases caused by viruses, rickettsiae, chlamydiae, mycoplasmas, bacteria, fungi, algae, protozoa, and unknown agents. Discussion of each disease includes diagnostic testing, indications and methods... |
 | The Woman with a Worm in Her Head: And Other True Stories of Infectious Disease by Pamela Nagami A normal, healthy woman becomes host to a pork tapeworm that is burrowing into her brain and disabling her motor abilities. A handsome man contracts Chicken Pox and ends up looking like the victim of a third degree burn. A vigorous young athlete is bitten by an insect and becomes a target for flesh-eating strep.Even the most innocuous everyday activities such as eating a salad for lunch, getting... |
 | Infectious Diseases: A Clinical Short Course (LANGE Clinical Medicine) by Frederick Southwick Gain a full understanding of clinical infectious diseases in just thirty days . . No other resource makes clinical infectious diseases more manageable and easy to master than Infectious Diseases: A Clinical Short Course. This one-of-a-kind self-instruction tool is organized by system/region as opposed to pathogens -- simulating how common pathogens and disorders would be encountered in rounds... |
 | Clinical Infectious Disease This clinically-oriented, user-friendly text is the best on the market for infectious disease. Complete and comprehensive, Schlossberg's text will be an effective reference for any practitioner who may encounter these afflictions. The orientation of the volume is multi-faceted: in addition to the traditional organization of organ system and pathogen-related information, this text includes... |
 | Principles and Practice of Pediatric Infectious Disease: Text with CD-ROM (Principles and Practice of Pediatric Infectious Diseases) by Sarah S. Long, Larry K. Pickering, Charles G. Prober Quickly find the data you need to understand a clinical problem, diagnose it correctly, and provide appropriate management! This reference offers the latest need-to-know information thanks to an easy-to-access format...allowing you to spend more time with your patients and less time searching for answers. A "who's who" of authorities from around the world provide you with the practical knowledge... |
 | Modeling Infectious Diseases in Humans and Animals by Matt J. Keeling, Pejman Rohani For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from... |
 | Emerging Infectious Diseases: Trends and Issues, Second Edition "This new work updates the highly regarded first edition...and is equally excellent. It offers a wealth of timely information about a variety of emerging and reemerging infections...This is an excellent reference for anyone interested in emerging infections, and will be a valuable resource for health science students, especially those in nursing and public health....Highly recommended.... |
 | The A to Z of Infectious Diseases (Concise Encyclopedia) by Carol Turkington, Bonnie Lee, M.d. Ashby In the past 25 years, more than 30 new germs affecting humans have emerged onto the medical scene, most of them rising from animals. New diseases like the avian flu, Ebola, SARS, and weaponized viruses such as anthrax and smallpox pose a growing danger to the world. With the threat of infectious diseases remaining constant, it is essential to have clear and concise information on this topic. "The... |
 | Infectious Disease: A Scientific American Reader (Scientific American Readers) The international public health scare that resulted last year when a man infected with multidrug-resistant tuberculosis flew overseas from the United States and back illustrates both the fear and the potential impact of highly infectious diseases in a global age. At a time when scientists warn of the potential for an influenza epidemic to rival the deadly outbreak of 1919 and newspapers feature... |
| © 2008 BrightSurf.com |