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Cholera vaccine could protect affected communities
November 27, 2007A vaccine used to protect travelers from cholera, an infection characterized by diarrhea and severe dehydration, could also be used effectively among those living in cholera-prone (endemic) areas, according to a research study by Ira Longini and colleagues published in PLoS Medicine. The study lends support to the idea that public-health officials should consider mass vaccination in their efforts to control endemic cholera.
Using a mathematical model for cholera transmission based on information from the Matlab region of Bangladesh, the researchers predicted that cholera outbreaks could be controlled by vaccinating as few as half of the population in an affected region. Because of "herd immunity" - protection of unvaccinated individuals due to the inability of cholera bacteria (Vibrio cholerae) to reach them via their vaccinated neighbors - the model indicated that vaccinating only 50% of the population could reduce the number of cholera cases among unvaccinated people by 89% and among the entire population by 93%. With only a third of the population vaccinated, the number of cases of cholera would still be predicted to fall by three-quarters.
In areas where there is less natural immunity to cholera-many people in Matlab are constantly exposed to V. cholerae, so they develop some immunity even without vaccination-70% of the population would probably need to be vaccinated to control cholera, according to the model.
The best way to prevent cholera, which is believed to cause about 100,000 deaths per year in developing countries, is to ensure that everyone has access to safe water and good sanitation, but these remain unavailable in many countries, and in situations of population displacement such as refugee camps and disasters such as floods.
Public Library of Science
The best way to prevent cholera, which is believed to cause about 100,000 deaths per year in developing countries, is to ensure that everyone has access to safe water and good sanitation, but these remain unavailable in many countries, and in situations of population displacement such as refugee camps and disasters such as floods.
Public Library of Science
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Love in the Time of Cholera (Vintage International) by Gabriel Garcia Marquez (Author) In their youth, Florentino Ariza and Fermina Daza fall passionately in love. When Fermina eventually chooses to marry a wealthy, well-born doctor, Florentino is devastated, but he is a romantic. As he rises in his business career he whiles away the years in 622 affairs--yet he reserves his heart for Fermina. Her husband dies at last, and Florentino purposefully attends the funeral. Fifty years, nine months, and four days after he first declared his love for Fermina, he will do so again. |
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Love in the Time of Cholera Starring: Javier Bardem, Giovanna Mezzogiorno, Benjamin Bratt, Gina Bernard Forbes, Marcela Mar Directed By: Mike Newell Also With: Andrew Molasky (Producer), Brantley M. Dunaway (Producer), Chris Law (Producer), Danny Greenspun (Producer), Dylan Russell (Producer), Gabriel García Márquez (Writer), Ronald Harwood (Writer) Based on the bestselling novel by Nobel Prize winning author, Gabriel Garcia Marquez, comes an epic love story that spans a lifetime, set against the breathtaking backdrop of South America during the turn of the century. When a teenage Florentino Ariza sees Fermina Daza for the first time, a spark of youthful infatuation ignites a romance that will carry the two from intoxicating highs to desperate lows over the next 50 years, in the film that dares to ask; How long would you wait for love? |
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The Cholera Years: The United States in 1832, 1849, and 1866 by Charles E. Rosenberg (Author) Cholera was the classic epidemic disease of the nineteenth century, as the plague had been for the fourteenth. Its defeat was a reflection not only of progress in medical knowledge but of enduring changes in American social thought. Rosenberg has focused his study on New York City, the most highly developed center of this new society. Carefully documented, full of descriptive detail, yet written with an urgent sense of the drama of the epidemic years, this narrative is as absorbing for general audiences as it is for the medical historian. In a new Afterword, Rosenberg discusses changes in historical method and concerns since the original publication of The Cholera Years. "A major work of interpretation of medical and social thought . . . this volume is also to be commended for its... |
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The Strange Case of the Broad Street Pump: John Snow and the Mystery of Cholera by Sandra Hempel (Author) In 1831, an unknown, horrifying, and deadly disease from Asia swept across continental Europe and North America, killing millions and throwing the medical profession into confusion. A killer with little respect for class or wealth, cholera ravaged the squalid streets of Soho and rocked the great centers of Victorian power. In this gripping book, Sandra Hempel tells the story of John Snow, a reclusive doctor without money or social position, who--alone and unrecognized--had the genius to look beyond the conventional wisdom of his day and uncover the truth behind the pandemic. She describes how Snow discovered that cholera was spread through drinking water and how this subsequently laid the foundations for the modern, scientific investigation of today's fatal plagues. A dramatic account... |
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The Ghost Map by Steven Johnson (Author) A thrilling historical account of the worst cholera outbreak in Victorian London-and a brilliant exploration of how Dr. John Snow's solution revolutionized the way we think about disease, cities, science, and the modern world. From the dynamic thinker routinely compared to Malcolm Gladwell, E. O. Wilson, and James Gleick, The Ghost Map is a riveting page-turner with a real-life historical hero that brilliantly illuminates the intertwined histories of the spread of viruses, rise of cities, and the nature of scientific inquiry. These are topics that have long obsessed Steven Johnson, and The Ghost Map is a true triumph of the kind of multidisciplinary thinking for which he's become famous-a book that, like the work of Jared Diamond, presents both vivid history and a powerful and... |
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Love in the Time of Cholera by Original Soundtrack Nobel Prize winning author Gabriel Garcia Marquez' novel comes to the big screen, starring Javier Bardem, Benjamin Bratt, and John Leguizamo. The film follows a love triangle set in turn of the century South America, where two lovers wait out careers, marriages, affairs, and deaths until they can reunite. The soundtrack showcases lush Columbian music with an authentically beautiful score by Antonio Pinto ("City Of God") and two new tracks, sung in Spanish, by Shakira. These songs were written exclusively for the film and are exclusive to this soundtrack. |
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The Medical Detective: John Snow, Cholera and the Mystery of the Broad Street Pump by Sandra Hempel (Author) In 1831, an unknown, horrifying and deadly disease from Asia swept across Continental Europe, killing millions in its path and throwing the medical profession into confusion. Cholera is a killer with little respect for class or wealth. When it arrived in Britain, its repercussions rocked Victorian England - from the filthy lanes of the Sunderland quayside and the squalid streets of Soho, to the great centres of power: the Privy Council, Whitehall and, the Royal Medical Colleges. One man - alone and unrecognised - uncovered the truth behind the pandemic and laid the foundations for the modern, scientific investigation of today's fatal plagues. John Snow was a reclusive doctor, without money or social position, who had the genius to look beyond the conventional wisdom of his day, and work... |
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The Answer to Infection Cholera (Primary Contributor) |
![El Amor En Tiempos de Colera (Love in the Time of Cholera) [NTSC/REGION 1 & 4 DVD. Import-Latin America]](http://ecx.images-amazon.com/images/I/41FOe9F6qDL._SL160_.jpg) |
El Amor En Tiempos de Colera (Love in the Time of Cholera) [NTSC/REGION 1 & 4 DVD. Import-Latin America] Directed By: Mike Newell Also With: Javier Bardem (Primary Contributor), Benjamin Bratt (Primary Contributor), Catalina Sandino Moreno (Primary Contributor), John Leguizamo (Primary Contributor), Giovanna Mezzogiorno (Primary Contributor), Ana Claudia Talancon (Primary Contributor), Laura Harring (Primary Contributor), Fernanda Montenegro (Primary Contributor) Product Description Based on the bestselling novel by Nobel Prize winning author Gabriel Garcia Marquez comes an epic love story that spans a lifetime set against the breathtaking backdrop of South America during the turn of the century. When a teenage Florentino Ariza sees Fermina Daza for the first time a spark of youthful infatuation ignites a romance that will carry the two from intoxicating highs to desperate lows over the next 50 years in the film that dares to ask; How long would you wait for love? SINOPSIS La Película: Adaptación de la novela de Gabriel García Márquez, una de las más grandes historias de amor jamás contadas, con Javier Bardem como protagonista. Los jóvenes Florentino Ariza y Fermina Daza están perdidamente enamorados el uno del otro, pero la condición... |
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Letters on the Cholera Morbus. Part I first published in 1831, and Part II in 1832. |
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