How do you know whether you are male or female?December 27, 2007New research published online this week in the open-access journal PLoS Biology investigates this basic and much-studied question in the fruit fly, and comes to a surprising new conclusion. In mammals, male or female development depends on the presence of the Y chromosome, which is only found in males because it includes masculinizing genes. But other animal groups have evolved different systems. James Erickson and Jerome Quintero at Texas A&M University studied the mechanism of sex determination in the fruit fly, Drosophila melanogaster. Previous studies in the fly suggested that it was the ratio of X chromosomes (the "female" chromosome, of which there are two copies in a female fly, and just one in a male) to the non-sex chromosomes (the autosomes) that determined the sex of a fly embryo. However, this new paper indicates that rather than being dependent on the ratio, it is the number of X chromosomes that is important. Sex is determined during a very specific and short stage in embryo development, and only two X chromosomes can produce enough of a signal to feminize the embryo during this window of opportunity. http://www.plosbiology.org Public Library of Science |
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| Related Chromosomes Current Events and Chromosomes News Articles Possible Link Studied Between Childhood Abuse and Early Cellular Aging Children who suffer physical or emotional abuse may be faced with accelerated cellular aging as adults, according to new research from Butler Hospital and Brown University. Scientists at UA, collaborating institutions decode maize genome Scientists from the University of Arizona led by Arizona Genomics Institute director Rod A. Wing and from collaborating institutions have deciphered the complete genetic code of the maize plant for the first time. New map of variation in maize genetics holds promise for developing new varieties A new study of maize has identified thousands of diverse genes in genetically inaccessible portions of the genome. New techniques may allow breeders and researchers to use this genetic variation to identify desirable traits and create new varieties that were not easily possible before. New Maize Map to Aid Plant Breeding Efforts In a massive survey of genetic diversity in maize, also known as corn, researchers across the United States, have developed a gene map that should pave the way to significant improvements in a plant that is a major source of food, fuel, animal feed and fiber around the world. Chromosomes dance and pair up on the nuclear membrane Meiosis - the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell - is a major crossroads in all organisms reproducing sexually. Largest gene study of childhood IBD identifies 5 new genes In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease. NIH-funded researchers transform embryonic stem cells into human germ cells Researchers funded in part by the National Institutes of Health have discovered how to transform human embryonic stem cells into germ cells, the embryonic cells that ultimately give rise to sperm and eggs. A solution to Darwin's 'mystery of the mysteries' emerges from the dark matter of the genome Biological species are often defined on the basis of reproductive isolation. Ever since Darwin pointed out his difficulty in explaining why crosses between two species often yield sterile or inviable progeny (for instance, mules emerging from a cross between a horse and a donkey), biologists have struggled with this question. Common weed could provide clues on aging and cancer A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from Texas A&M University and the University of Cincinnati (UC). CSHL-led team discovers rare mutation dramatically increasing schizophrenia risk An international team of researchers led by geneticist Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL), has identified a mutation on human chromosome 16 that substantially increases risk for schizophrenia. More Chromosomes Current Events and Chromosomes News Articles |
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