How do you know whether you are male or female?December 27, 2007New research published online this week in the open-access journal PLoS Biology investigates this basic and much-studied question in the fruit fly, and comes to a surprising new conclusion. In mammals, male or female development depends on the presence of the Y chromosome, which is only found in males because it includes masculinizing genes. But other animal groups have evolved different systems. James Erickson and Jerome Quintero at Texas A&M University studied the mechanism of sex determination in the fruit fly, Drosophila melanogaster. Previous studies in the fly suggested that it was the ratio of X chromosomes (the "female" chromosome, of which there are two copies in a female fly, and just one in a male) to the non-sex chromosomes (the autosomes) that determined the sex of a fly embryo. However, this new paper indicates that rather than being dependent on the ratio, it is the number of X chromosomes that is important. Sex is determined during a very specific and short stage in embryo development, and only two X chromosomes can produce enough of a signal to feminize the embryo during this window of opportunity. http://www.plosbiology.org Public Library of Science |
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| Related Chromosomes Current Events and Chromosomes News Articles Childhood adversity may promote cellular aging Children who suffer physical or emotional abuse could be faced with accelerated cellular aging as adults, according to new research published by Elsevier in Biological Psychiatry. A better genetic test for autism A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three times the detection rate for genetic changes related to autism spectrum disorders (ASDs) than standard tests. Publishing in the April issue of Pediatrics (and online March 15), the authors urge that CMA become part of the first-line genetic work-up for ASDs. Sequencing genome of entire family reveals parents give kids fewer gene mutations than was thought Researchers at the University of Utah and other institutions have sequenced for the first time the entire genome of a family, enabling them to accurately estimate the average rate at which parents pass genetic mutations to their offspring and also identify precise locations where parental chromosomes exchange information that creates new combinations of genetic traits in their children. Scientists solve puzzle of chickens that are half male and half female A puzzle that has baffled scientists for centuries - why some birds appear to be male on one side of the body and female on the other - has been solved by researchers. First whole genome sequencing of family of 4 reveals new genetic power The Institute for Systems Biology (ISB) has analyzed the first whole genome sequences of a human family of four. Infectious virus hidden in chromosomes during latency can be passed from parents to children Human herpesvirus 6 (HHV-6) infects nearly 100 percent of humans in early childhood, and the infection then lasts for the rest of a person's life. Asexual plant reproduction may seed new approach for agriculture Farmers throughout the world spend an estimated $36 billion a year to buy seeds for crops, especially those with sought after traits such as hardiness and pest-resistance. Modern man found to be generally monogamous, moderately polygamous Did women and men contribute equally to the lineage of contemporary populations? Did our ancestors, Homo sapiens, lean more toward polygamy or monogamy? Pesticide atrazine can turn male frogs into females Atrazine, one of the world's most widely used pesticides, wreaks havoc with the sex lives of adult male frogs, emasculating three-quarters of them and turning one in 10 into females, according to a new study by University of California, Berkeley, biologists. Cells of Aggressive Leukemia Hijack Normal Protein to Grow, According to Penn Study Researchers have found that one particularly aggressive type of blood cancer, mixed lineage leukemia (MLL), has an unusual way to keep the molecular motors running. The cancer cells rely on the normal version of an associated protein to stay alive. More Chromosomes Current Events and Chromosomes News Articles |
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