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Donors' health associated with risk of infection among recipients of corneal transplants
February 12, 2008Corneal grafts obtained from donors dying in the hospital or with cancer may be associated with an increased risk of infection for the recipient, according to a report in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
"Infection is an uncommon but serious complication of corneal transplant," the authors write as background information in the article. "Most infected eyes lose vision or become blind." Various practices have been instituted to reduce the risk of infection, including refusing donors who have blood or other infections and retrieving and preserving tissue with antiseptic tools.
During the 10 years of the study, eye banks distributed 340,174 donor corneas in the United States and 109,009 internationally. A total of 162 cases of endophthalmitis were reported. The odds of infected recipients having received a cornea from a hospitalized donor were three times that of non-infected recipients. In addition, death of the donor from cancer was considerably more likely among the recipients who developed infections. The cause is unclear, but donors could acquire harmful microorganisms in the hospital and transmit them to the patients, the authors note.
The results provide evidence that the donor's health before death may affect their eye tissue, but do not warrant excluding broad categories of donors, the authors note. "Blanket deferral from donation by hospitalized patients or those with cancer would be unreasonable as most corneas from these donors do not result in complications," they write. "Rather, efforts are needed to determine what illnesses, interventions or other reasons might explain the pathway linking certain donors with recipient infection. We advocate judicious evaluation of decedents and encourage efficient recovery and delivery of donated tissues, but we also recognize an opportunity for better methods of microbiological assessment and control to reduce infections associated with corneal transplant."
JAMA and Archives Journals
Corneal Transplant Current Events and Corneal Transplant News RSSSafety, efficacy of corneal transplant procedure confirmed; an antibiotic can cause double vision
Highlights of September's Ophthalmology, the journal of the American Academy of Ophthalmology (Academy), include a 2009 review by the Academy of the safety and efficacy of a widely used corneal transplant procedure and a warning about an unusual but serious reaction to systemic fluroquinolones, a class of antibiotics used to treat a variety of bacterial infections.
Clue to normal-tension glaucoma; herpes infection and corneal transplants
The July issue of Ophthalmology, the journal of the American Academy of Ophthalmology, includes two studies that may influence clinical treatment of serious eye conditions.
Stem cell therapy makes cloudy corneas clear, according to Pitt researchers
Stem cells collected from human corneas restore transparency and don't trigger a rejection response when injected into eyes that are scarred and hazy, according to experiments conducted in mice by researchers at the University of Pittsburgh School of Medicine.
Potential new herpes therapy studied
A new therapy being developed at the University of Florida could, in time, produce another weapon for the fight against herpes.
New research on how season of birth may affect nearsightedness and on cornea donor sources
Does season of birth play a role in the development of nearsightedness? Do corneas from older donors meet quality standards for transplant surgery? These are among the topics explored in the April 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.
A new method of adult stem cell growth efficacious in treatment of disorders of the cornea
A new method of adult stem cell growth, designed in the Area of Cellular Therapy of the University Clinic (University of Navarra), has demonstrated its efficacy for its capacity to grow cornea stem cells.
Artificial cornea offers better results for infants, some blind patients
Infants and adults who are blind due to a cloudy or damaged cornea are seeing some remarkable results thanks to a new version of an artificial implant that takes the place of the cornea, the clear covering of the eye that serves as our window on the world.
Advances In Curing Corneal Illnesses Using Stem Cells
The University School of Clinical Medicine has developed a new technique for the treatment of corneal illnesses. It involves transplanting from the cornea stem cells which have previously been grown in the laboratory. According to the explanation provided by Doctor Javier Moreno, director of Ophthalmology and Doctor Felipe Pr'łsper, responsible for Cellular Therapy at the University School of Clinical Medicine, "the surgical technique employed is similar to that published in other countries. The importance here lies in the novel growth method for the culture of corneal stem cells. This culture system provides the advantage of achieving cells of particular quality, which influences recovery
Nerve Centre Opens in Manchester: media invitation
Research which will greatly improve patient recovery from nerve damage following accidents, will take a major step forward with the opening of dedicated laboratories at The University of Manchester on Thursday 13 November at 2.30pm. The Blond McIndoe Nerve Regeneration Group, formerly based at The Royal Free and University College Medical School, London, relocated to Manchester earlier this year and is now moving into purpose-designed £500,000 laboratories at the University, providing state-of-the-art facilities for more scientists to carry out their pioneering work in this important area. It joins the Department of Plastic & Reconstructive Surgery Research team, headed by Professor Gu
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The Official Patient's Sourcebook on Corneal Transplant Surgery by James N. Parker (Editor), Philip M. Parker (Editor) This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to corneal transplant surgery (also keratoplasty; penetrating keratoplasty), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on corneal transplant surgery. Given patients'... |
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Blink Starring: Madeleine Stowe, Aidan Quinn, James Remar, Peter Friedman, Bruce A. Young Directed By: Michael Apted A blind woman, whose sight has only recently been restored, thinks she's witnessed a brutal murder. Starring Madeline Stowe and Aidan Quinn. Directed by Michael Apted. Year: 1994 Director: Michael pted Starring: Madeleine Stowe, Aidan Quinn, James Remar |
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The Sixty-Minute Triple / A Simple Technique for Centering the Recipient Trephine in Corneal Transplant [VHS] Starring: Alan N. Carlson, Hamid Sajjadi | |
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Eye Surgery, Corneal Transplant Photographic Poster Print, 24x18 by Art.com Art.com is the world's largest retailer of art prints, posters, photographs, and framed artwork. With our huge selection of over 400,000 prints, you'll easily find the perfect piece for your home, office, or classroom. Our art is printed on quality paper. When you order framed artwork, the piece is built by our team of in-house professionals. Visit our Amazon store today at www.amazon.com/artdotcom to find Special Offers and search for products based on 'Artist Name' and 'Subject Categories' such as Movie, Music, Vintage, TV, Children, Travel, Kitchen, Museum Art, Animals, Floral, Motivational, and Sports. Art.com is dedicated to providing you with high quality products and service by offering you 100% satisfaction guaranteed. We ship internationally to over 80 countries. Decorate your... |
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Artificial Cornea in Sight.(source of tissue for corneal transplants is cadavers)(white blood cells that fight infection): An article from: Transplant News by Gale Reference Team (Author) This digital document is an article from Transplant News, published by Thomson Gale on November 1, 2006. The length of the article is 508 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Artificial Cornea in Sight.(source of tissue for corneal transplants is cadavers)(white blood cells that fight infection) Author: Gale Reference Team Publication: Transplant News (Newsletter) Date: November 1, 2006 Publisher: Thomson Gale Volume: 16 Issue: 19 Distributed by Thomson... | |
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Possessed Starring: Nicollette Sheridan Ann Culver (Nicollette Sheridan) lost her sight and her unborn child in an accident. Although her vision was restored through surgical transplants, the lost of her baby remains a painful void. Is that the underlying cause of Ann’s nightmares or has she been given a second sight; an insight to the life and brutal murder of her organ donor Julie Zack? Soliciting the aid of Jasmine, an eccentric psychic, Ann hones in on the killer and her nightmares become a reality that she may not survive. |
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Eye Surgery, Corneal Transplant Photographic Poster Print, 32x24 by AllPosters.com AllPosters.com is the world's #1 seller of posters, prints, photographs, specialty products and framed art. We're dedicated to bringing our customers the best selection of high quality wall décor that is perfect for their home or office. Browse our catalog of over 300,000 items that include entertainment and specialty posters, decorative prints, and art reproductions. Whether you're looking for your favorite movie or music poster, a framed Monet reproduction, or a print of the Eiffel Tower you will find it at AllPosters.com. Visit our Amazon store today at www.amazon.com/allposters to find Special Offers and search by subject category or artist. AllPosters.com provides unmatched service with a 100% satisfaction guarantee. We ship internationally to over 80 countries. Decorate your... |
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Scientists successfully transplant bioengineered corneal stem cells into vision impaired patients.(Brief Article): An article from: Transplant News by Michele Grygotis (Author) This digital document is an article from Transplant News, published by Transplant Communications, Inc. on July 29, 2000. The length of the article is 1045 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Scientists successfully transplant bioengineered corneal stem cells into vision impaired patients.(Brief Article) Author: Michele Grygotis Publication: Transplant News (Newsletter) Date: July 29, 2000 Publisher: Transplant Communications, Inc. Volume: 10 Issue: 14 Page: NA Article Type: Brief Article Distributed by Thomson... | |
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Eye Surgery, Corneal Transplant Photographic Poster Print, 32x24 by Art.com Art.com is the world's largest retailer of art prints, posters, photographs, and framed artwork. With our huge selection of over 400,000 prints, you'll easily find the perfect piece for your home, office, or classroom. Our art is printed on quality paper. When you order framed artwork, the piece is built by our team of in-house professionals. Visit our Amazon store today at www.amazon.com/artdotcom to find Special Offers and search for products based on 'Artist Name' and 'Subject Categories' such as Movie, Music, Vintage, TV, Children, Travel, Kitchen, Museum Art, Animals, Floral, Motivational, and Sports. Art.com is dedicated to providing you with high quality products and service by offering you 100% satisfaction guaranteed. We ship internationally to over 80 countries. Decorate your... |
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