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Newly discovered role of thyroid hormone during pregnancy
February 20, 2008Thyroid hormone deficiencies in early pregnancy can cause locomotor underdevelopment in the child, according to research from the Swedish medical university Karolinska Institutet. The results bring new insights into brain development and could affect routine pregnancy testing.
Children born with thyroid hormone deficiencies (hypothyreosis) are in danger of mental and locomotor underdevelopment if they remain untreated. However, scientists are unsure about what causes the damage and about how much attention should be given to the mother's hormone levels during pregnancy. In Sweden, all newborn babies, but not all pregnant women, are tested for hypothyreosis.
"Hypothyreosis is easy to treat if it's discovered," says Professor Björn Vennström, who has led the study. "The results provide fresh support for those who advocate the more thorough monitoring of pregnant women."
The scientists were also able to show that the cause of the locomotor disorders was an abnormal development of specific nerve cells in the motor cortex and cerebellum. The findings thus give new and important insights into the part played by thyroid hormone in brain development.
The study used gene modified mice with a mutation in one of the two receptors for thyroid hormone. The discoveries mean that patients with mutations of the same receptor can, for the first time, be identified and treated.
Karolinska Institutet
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6 environmental research studies reveal critical health risks from plastic
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Thyrotropin levels associated with Alzheimer's disease risk in women
Women with low or high levels of the hormone thyrotropin, which affects thyroid gland function and thyroid hormone levels, appear to have a higher risk of developing Alzheimer's disease, according to a report in the July 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Thyroid treatment no 'quick fix' for weight loss in children
Children treated for hypothyroidism aren't likely to drop pounds with treatment for the condition says a new study in the Journal of Pediatrics. The study is the first to examine the link between hypothyroidism treatment and weight loss in pediatric patients.
New strategy to cut heart attack risk is effective in initial test
The first clinical trial of a new kind of drug to cut the risk of cardiovascular disease has been found safe and effective at dropping levels of "bad" low density lipoprotein (LDL) cholesterol by as much as 40 percent.
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The Thyroid Hormone Breakthrough: Overcoming Sexual and Hormonal Problems at Every Age by Mary J. Shomon (Author) If you're one of the millions of American women suffering from PMS, irregular periods, difficulty getting pregnant, low sex drive, postpartum depression, menopausal symptoms, or many other hormonal problems, what you may not realize is that thyroid disease could be the culprit. The Thyroid Hormone Breakthrough is a holistic guide to identifying and overcoming the connection between hormonal problems and the thyroid, which goes undiagnosed in more than 30 million women in the U.S. alone. It will help you identify and diagnose thyroid problems and offer strategies to cope with the effects that thyroid conditions can have on everything from puberty to menopause, including ways to avoid the pitfalls of decreased sex drive. With information on diet and exercise, conventional and... |
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