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Does gingko biloba affect memory?
February 28, 2008ST. PAUL, Minn. - Taking the supplement ginkgo biloba had no clear-cut benefit on the risk of developing memory problems, according to a study published in the February 27, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The three-year study involved 118 people age 85 and older with no memory problems. Half of the participants took ginkgo biloba extract three times a day and half took a placebo. During the study, 21 people developed mild memory problems, or questionable dementia: 14 of those took the placebo and seven took the ginkgo extract. Although there was a trend favoring ginkgo, the difference between those who took gingko versus the placebo was not statistically significant.
The researchers made an interesting observation when they examined the data at the end of the trial. Taking into account whether people followed directions in taking the study pills, they found that people who reliably took the supplement had a 68 percent lower risk of developing mild memory problems than those who took the placebo. Without further study, it is unclear if this difference is real or just a chance occurrence.
On a cautionary note, the study also found that people taking ginkgo biloba were more likely to have a stroke or transient ischemic attack, or mini stroke. Seven people taking ginkgo had strokes, while none of those taking placebo did. "Ginkgo has been reported to cause bleeding-related complications, but the strokes in this case were due to blood clots, not excessive bleeding, and were generally not severe," said study author Hiroko Dodge, PhD, of the Department of Public Health and Center for Healthy Aging Research at Oregon State University in Corvallis.
"These results need to be clarified with larger studies, but the findings are interesting because ginkgo biloba is already widely used, readily available, and relatively inexpensive," said Dodge. "One of the most pressing public health problems facing our society is the rapidly growing number of people who, due to their age alone, are at high risk of developing dementia. The potential to delay or prevent this is of great importance. Further studies are needed to determine whether gingko biloba has any benefits in preventing cognitive decline and whether it is safe."
Dodge noted that this is the first randomized, controlled trial of prevention of dementia in people age 85 and older.
American Academy of Neurology
On a cautionary note, the study also found that people taking ginkgo biloba were more likely to have a stroke or transient ischemic attack, or mini stroke. Seven people taking ginkgo had strokes, while none of those taking placebo did. "Ginkgo has been reported to cause bleeding-related complications, but the strokes in this case were due to blood clots, not excessive bleeding, and were generally not severe," said study author Hiroko Dodge, PhD, of the Department of Public Health and Center for Healthy Aging Research at Oregon State University in Corvallis.
"These results need to be clarified with larger studies, but the findings are interesting because ginkgo biloba is already widely used, readily available, and relatively inexpensive," said Dodge. "One of the most pressing public health problems facing our society is the rapidly growing number of people who, due to their age alone, are at high risk of developing dementia. The potential to delay or prevent this is of great importance. Further studies are needed to determine whether gingko biloba has any benefits in preventing cognitive decline and whether it is safe."
Dodge noted that this is the first randomized, controlled trial of prevention of dementia in people age 85 and older.
American Academy of Neurology
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Ginkgo Biloba Extract 60 mg 240 Caps by Swanson Premium Brand Give your brain an herbal boost with Ginkgo biloba! Extracts of Ginkgo biloba leaves have been used in China for almost 5,000 years as a natural way to support memory and mental sharpness. Our Ginkgo extract is standardized to contain 24% flavone glycosides and 6% terpene lactones for guaranteed potency in each capsule. Limit 3 Bottles |
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Nature's Bounty Ginkgo Biloba, 60 mg, Standardized Extract, 120 Tablets (Pack of 2) by Nature's Bounty Herbal Supplement. Promotes Healthy Brain Function. Scientific research documents the ability of Ginkgo to maintain peripheral circulation to the arms, legs and brain. In addition, Ginkgo helps improve memory, especially occasional mild memory problems as |
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Nature's Bounty Ginkgo Biloba, Standardized Extract, 240 Tablets (Pack of 2) by Nature's Bounty Herbal Supplement. Promotes Healthy Brain Function. Scientific research documents the ability of Ginkgo to maintain peripheral circulation to the arms, legs and brain. In addition, Ginkgo helps improve memory, especially occasional mild memory problems associated with aging. Ginkgo also possesses antioxidant properties that may help neutralize cell-damaging free radicals. Studies have shown that oxidative stress caused by free radicals may contribute to aging. To enhance the bioactivity of the standardized Ginkgo, we've added 400 mg of Ginkgo Leaf per serving. Value Size. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.) |
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Nature Made Ginkgo Biloba Extra-Count Bottles Capsules, 60 mg, 60-Count Bottles (Pack of 3) by Nature Made Nature's Resource Ginko Biloba (Ginkgo biloba). Studies indicate Ginkgo may increase peripheral circulation, thereby enhancing blood flow to the arms, legs and brain. Ginkgo helps maintain healthy memory function and mental alertness. |
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Ginkgo Biloba Extract 60 mg 120 Caps by Swanson Premium Brand Give your brain an herbal boost with Ginkgo biloba! Extracts of Ginkgo biloba leaves have been used in China for almost 5,000 years as a natural way to support memory and mental sharpness. Our Ginkgo extract is standardized to contain 24 percent flavone glycosides and six percent terpene lactones for guaranteed potency in each capsule. Limit 3 Bottles |
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Source Naturals Ginkgo-24, 120 mg, Tablets, 120 tablets by Source Naturals Dietary supplement. Ginkgo Biloba Extract. 24% Flavone Glycosides; 6% Terpene Lactones. Ginkgo-24 is a standardized concentration of prime quality Ginkgo biloba leaves. The extraction yields 24% ginkgo flavone glycosides (the key nutrients) from a 50 to 1 concentration. The Ginkgo biloba tree has survived for over 200 million years, virtually unchanged - the Earth's oldest living species of tree. Ginkgo biloba is the subject of extensive scientific research, and is used worldwide as a nutritional supplement. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.) |
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Spring Valley - Ginkgo Biloba 120 mg, 90 Capsules by Nature's Bounty, Inc. Scientific research documents the ability of Ginkgo to maintain peripheral circulation to the arms, legs and brain. In addition, Ginkgo helps improve memory, especially occasional mild memory problems associated with aging. Ginkgo also possesses antioxidant properties that may help neutralize cell-damaging free radicals. Studies have shown that oxidative stress caused by free radicals may contribute to aging. |
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Super Ginkgo Plus Ginko 100 Tablets (125mg Leaf Extract plus 310mg Leaf), ONLY $1.25 Shipping per Bottle, Buy 4 Bottles SHIPPING IS FREE! Dollar for dollar you get 3 X the Ginkgo as Swanson Ginkgo Biloba Extract 60mg 240 Caps! by ValuePricedMeds HOW GINGKO WORKS: The ginkgo flavonoids act specifically to dilate the smallest segment of the circulatory system, the micro-capillaries, which has a widespread affect on the organs, especially the brain. Researchers have also reported that Ginkgo extracts effectively increase blood circulation and increase oxygen levels in brain tissues. Ginkgo is also a powerful antioxidant that prevents platelet aggregation inside arterial walls, keeping them flexible and decreasing the formation of arteriosclerositic plaque. Recently western researchers have been studying ginkgo biloba as a treatment for senility, hardening of the arteries, and as a treatment for oxygen deprivation. More than 34 human and hundreds of animal and chemical studies on Ginkgo Biloba have been published since 1975, showing,... |
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TruNature Ginkgo Biloba with Vinpocetine, 60mg (250 Softgels) by TruNature Supports alertness & short term memory. Ginkgo Biloba can help mental clarity and memory retention. Research has shown that Ginkgo Biloba works as an antioxidant and contains flavone glycosides and terpenes that can help MAintain healthy blood flow to the |
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Now Foods Ginkgo Biloba, 100 Capsules / 120mg by NOW NOW® Ginkgo Biloba is grown and extracted under the highest quality standards and is standardized to min. 24% Ginkgoflavonglycosides and min. 6% Terpene Lactones, including Ginkgolide B, the most significant fraction, and Ginkgolides A, C and Bilobalide. |
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