Researchers have discovered a gene that can block the spread of HIVFebruary 29, 2008
Dr. Stephen Barr, a researcher in the Department of Medical Microbiology & Immunology at the U of A, says his team identified a human gene called TRIM22 that can block HIV infection in a cell culture by preventing the assembly of the virus. Barr says "interestingly, when we prevent cells from turning on TRIM22, the normal interferon response (a natural defense produced by our cells to fight infection by viruses such as HIV) is useless at blocking HIV infection. This means TRIM22 is an essential part of our body's ability to fight off HIV."
Barr's team finds the results very exciting because it shows our bodies have a gene that is capable of stopping the spread of HIV. They are now trying to figure out why this gene does not work in people infected with HIV and if there is a way to turn this gene on in those individuals. "We hope that our research will lead to the design of new drugs and/or vaccines that can halt the person-to-person transmission of HIV and the spread of the virus in the body, thereby blocking the onset of AIDS."
University of Alberta
Related AIDS Current Events and AIDS News Articles
Main reason for lifespan variability between races not cause of death
Eliminating health disparities between races is a goal of many groups and organizations, but a team of sociologists suggests that finding the reasons for the differences in the timing of black and white deaths may be trickier than once thought.
Single genetic abnormality accelerates, removes the brakes on Ewing sarcoma tumor growth
The genetic abnormality that drives the bone cancer Ewing sarcoma operates through two distinct processes - both activating genes that stimulate tumor growth and suppressing those that should keep cancer from developing.
Medicaid is a very good investment even if it does not lower cholesterol or blood pressure
Researchers at Columbia University's Mailman School of Public Health analyzed the results of the Oregon Health Experiment, where eligible uninsured individuals were randomly assigned Medicaid or to stay with their current care.
Combining social media and behavioral psychology could lead to more HIV testing
Social media such as Twitter and Facebook can be valuable in the fight against HIV in the United States, where research has demonstrated they can prompt high-risk populations to request at-home testing kits for the virus that causes AIDS, suggesting a way to potentially boost testing rates.
Scientists' unique system of oral vaccine delivery to address global health threats
Scientists at The Forsyth Institute and Tufts University have succeeded in describing and validating a unique system of oral vaccine delivery using a common bacteria found in the mouth.
Occasional heroin use may worsen HIV infection
Researchers at Yale and Boston University and their Russian collaborators have found that occasional heroin use by HIV-positive patients may be particularly harmful to the immune system and worsens HIV disease.
Geospatial study identifies hotspots in deaths from HIV/AIDS and Hepatitis C in Massachusetts
A new study from epidemiologists at Tufts University School of Medicine helps to identify communities with the greatest public health need in Massachusetts for resources relating to HIV/AIDS and hepatitis C.
Targeting mitochondrial enzyme may reduce chemotherapy drug's cardiac side effects
Massachusetts General Hospital (MGH) investigators have identified two compounds that appear, in cellular and animal models, to block the cardiac damage caused by the important chemotherapy drug doxorubicin.
Long-term results confirm success of MGH-developed laser treatment for vocal-cord cancer
The first long-term study of a pioneering endoscopic laser treatment for early vocal-cord cancer, developed at Massachusetts General Hospital (MGH) and previously shown to provide optimal voice outcomes, finds that it is as successful as traditional approaches in curing patients' tumors while avoiding the damage to vocal quality caused by radiotherapy or by conventional laser or cold-instrument surgery.
Study finds Affordable Care Act leaves many children without important benefits
An article published in the Health Affairs December issue is the first ever comprehensive analysis to investigate the Affordable Care Act's (ACA) Essential Health Benefit (EHB) as it relates to children.
More AIDS Current Events and AIDS News Articles