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Henry Ford Hospital to study effectiveness of a new procedure that may help emphysema suffers
March 13, 2008DETROIT MI- Researchers at Henry Ford Hospital today announced the start of the EASE (Exhale Airway Stents for Emphysema) Trial, an international, multi-center clinical trial to explore an investigational treatment that may offer a significant new option for those suffering with advanced emphysema. The study focuses on a new procedure, called airway bypass, that involves creating pathways in the lung for trapped air (one of the primary causes of shortness breath) to escape.
Henry Ford is the only hospital in Detroit participating in the study.
Chronic obstructive pulmonary disease (COPD) is a term referring to two lung diseases, chronic bronchitis and emphysema, that are characterized by obstruction to airflow that interferes with normal breathing. COPD is the fourth leading cause of death in the United States and is projected to be the third leading cause of death for men and women by the year 2020. There is no cure for COPD.
Emphysema is an irreversible disease characterized by the destruction of lung tissue and a subsequent decrease of the lung's natural elasticity, which causes the small airways of the lungs to collapse. Shortness of breath worsens as this process progresses, eventually leading to a situation where all of the inhaled air cannot be exhaled, and in essence air becomes trapped in the chest. This "hyperinflation" significantly contributes to the shortness of breath experienced by patients with emphysema.
"We are excited to be part of this study because currently there are limited treatment options for most patients with emphysema beyond lung transplantation. Patients usually have very poor quality of life, as each breath can be difficult," says Michael Simoff, M.D., a Henry Ford pulmonologist and principal investigator of the study.
"By creating new pathways for airflow with the airway bypass procedure, we hope to reduce hyperinflation and all the problems it causes for patients. If patients can breathe easier, our work will be worth it."
Physicians commonly use bronchoscopes to examine the airways within the lungs. During the airway bypass procedure physicians will first use a Doppler probe inserted through the bronchoscope to identify a site in the airway that is free of blood vessels. A special needle is then used to make a small opening and an Exhale® Drug-Eluting Stent is placed in the passageway to keep it open. The procedure involves placing up to six drug-eluting stents. The total time of the procedure is approximately two hours.
"The airway bypass procedure could be an excellent option for those who are not suitable candidates for lung transplant surgery or as a bridge for those who could possibly spend years on a lung transplant list," Dr. Simoff says.
Broncus Technologies
Emphysema is an irreversible disease characterized by the destruction of lung tissue and a subsequent decrease of the lung's natural elasticity, which causes the small airways of the lungs to collapse. Shortness of breath worsens as this process progresses, eventually leading to a situation where all of the inhaled air cannot be exhaled, and in essence air becomes trapped in the chest. This "hyperinflation" significantly contributes to the shortness of breath experienced by patients with emphysema.
"We are excited to be part of this study because currently there are limited treatment options for most patients with emphysema beyond lung transplantation. Patients usually have very poor quality of life, as each breath can be difficult," says Michael Simoff, M.D., a Henry Ford pulmonologist and principal investigator of the study.
"By creating new pathways for airflow with the airway bypass procedure, we hope to reduce hyperinflation and all the problems it causes for patients. If patients can breathe easier, our work will be worth it."
Physicians commonly use bronchoscopes to examine the airways within the lungs. During the airway bypass procedure physicians will first use a Doppler probe inserted through the bronchoscope to identify a site in the airway that is free of blood vessels. A special needle is then used to make a small opening and an Exhale® Drug-Eluting Stent is placed in the passageway to keep it open. The procedure involves placing up to six drug-eluting stents. The total time of the procedure is approximately two hours.
"The airway bypass procedure could be an excellent option for those who are not suitable candidates for lung transplant surgery or as a bridge for those who could possibly spend years on a lung transplant list," Dr. Simoff says.
Broncus Technologies
Emphysema Current Events and Emphysema News RSSU.S. and European Experts Applaud Creation of New Transatlantic Task Force on Global Antibiotic Resistance Threat
Experts on both sides of the Atlantic applaud President Barack Obama and Swedish Prime Minister Fredrik Reinfeldt, representing the European Union (EU) Presidency, for establishing a transatlantic task force to address antibiotic resistance, an urgent and growing problem that threatens patient safety and public health worldwide.
Stereotactic radiotherapy offers noninvasive, effective treatment for frail patients with early-stage lung cancer
Stereotactic body radiation therapy (SBRT) should be considered a new standard of care for early-stage lung cancer treatment in patients with co-existing medical problems, according to results from a national clinical trial led by UT Southwestern Medical Center physicians.
Survey: Awareness of COPD is rising, but understanding is still low
Awareness of COPD-chronic obstructive pulmonary disease-continues to grow in the United States, according to national survey results released today by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.
UT scientists discover link between protein and lung disease
In a development that could lead to a novel approach to the treatment of a devastating lung disease, biochemists at The University of Texas Health Science Center at Houston report they are the first to link the osteopontin (OPN) protein to chronic obstructive pulmonary disease (COPD).
New genes at work in patients with hereditary lung disease
University of Florida researchers have safely given new, functional genes to patients with a hereditary defect that can lead to fatal lung and liver diseases, according to clinical trial findings slated to appear this week in the online early edition of the Proceedings of the National Academy of Sciences.
New genes at work in patients with hereditary lung disease
Researchers at the University of Massachusetts Medical School and the University of Florida in Gainesville have safely given new, functional genes to patients with a hereditary defect that can lead to fatal lung and liver diseases.
Scientists open doors to diagnosis of emphysema
Chronic inflammatory lung diseases like chronic bronchitis and emphysema are a major global health problem, and the fourth leading cause of death and disability in developed countries, with smoking accounting for 90% of the risk for developing them.
Emphysema severity directly linked to coal dust exposure
Coal dust exposure is directly linked to severity of emphysema in smokers and nonsmokers alike, according to new research from the National Institute for Occupational Safety and Health (NIOSH).
Lung volume reduction surgery shown to prolong and improve life for some emphysema patients
Lung volume reduction surgery (LVRS) can have a significantly beneficial effect in patients with severe emphysema, according to the first ever study to randomize emphysema patients to receive either LVRS or non-surgical medical care.
Protein may be strongest indicator of rare lung disease, study shows
Researchers at the University of Cincinnati (UC) have discovered a protein in the lungs that can help in determining progression of the rare lung disease Idiopathic Pulmonary Fibrosis (IPF).
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Facelake Fingertip Finger Pulse Oximeter and Heart Rate Monitor. Used for Copd, Emphysema, Aviation, Sports Training, High Altitude Sports, free carry case by Facelake This Pulse Oximeter is a compact, light weighted device, designed for on the go spot checking of vital signs (blood O2 saturation & pulse rate), in a simple non-invasive procedure. By simply clipping the device to the finger, users can receive a SpO2 and pulse reading, within seconds. The Pulse Oximeter answers a wide range of needs and serves various roles in the medical and recreational fields. 2 years warranty. |
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