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Ultra-fast, ultra-intense laser has clean-cut advantage
March 14, 2008
COLUMBIA, Mo. - Many people equate lasers with a sci-fi battle in a galaxy far, far away or, closer to home, with grocery store scanners and compact disc players. However, an ultra-fast, ultra-intense laser, or UUL, with laser pulse durations of one quadrillionth of a second, otherwise known as one femtosecond, could change cancer treatments, dentistry procedures, precision metal cutting, and joint implant surgeries. "The femtosecond laser has now entered the era of applications. It used to be a novelty, a fantasy," said University of Missouri researcher Robert Tzou, the James C. Dowell professor and chairman of the department of Mechanical and Aerospace Engineering. "We are currently targeting the areas of life-science and bio-medicine."
What makes the femtosecond laser different from other lasers is its unique capacity to interact with its target without transferring heat to the area surrounding its mark. The intensity of the power gets the job done while the speed ensures heat does not spread. Results are clean cuts, strong welds and precision destruction of very small targets, such as cancer cells, with no injury to surrounding materials. Tzou hopes that the laser would essentially eliminate the need for harmful chemical therapy used in cancer treatments.
"If we have a way to use the lasers to kill cancer cells without even touching the surrounding healthy cells, that is a tremendous benefit to the patient," Tzou said. "Basically, the patient leaves the clinic immediately after treatment with no side effects or damage. The high precision and high efficiency of the UUL allows for immediate results."
Practical applications of this type of laser also include, but aren't limited to, the ability to create super-clean channels in a silicon chip. That process can allow doctors to analyze blood one cell at a time as cells flow through the channel. The laser can be used in surgery to make more precise incisions that heal faster and cause less collateral tissue damage. In dentistry, the laser can treat tooth decay without harming the rest of the tooth structure.
Associate Professor Yuwen Zhang and Professor Jinn-Kuen Chen recently received a grant from the National Science Foundation to use the laser to "sinter" metal powders-turn them into a solid, yet porous, mass using heat but without massive liquefaction-a process which can help improve the bond between joint implants and bone.
"With the laser, we can melt a very thin strip around titanium micro- and nanoparticles and ultimately control the porosity of the bridge connecting the bone and the alloy," Zhang said. "The procedure allows the particles to bond strongly, conforming to the two different surfaces."
Tzou said the installation of a new laser laboratory at MU will enable research teams to "aggressively pursue success at a national level." The femtosecond laser lab, components of which were installed in January, was made possible through a gift from engineering alumnus Bill Thompson and his wife Nancy. Tzou noted that the arrival of the lab at MU has initiated additional funding requests that will utilize the new femtosecond laser in research. Zhang, Chen and engineering professor Frank Feng also were the recipients of a United States Department of Defense grant to research possible military applications of the UUL.
Tzou said most research with femtosecond lasers, thus far, has focused on engineering materials such as metals and semiconductors. Because of the unique infrastructure at MU, where the college of engineering and the medical school are located on the same campus, Tzou has been able to attract faculty members who have renowned expertise in medicine and laser technology to collaborate.
University of Missouri-Columbia
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Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers
by Ella Faktorovich MD (Author)
Femtodynamics: A Guide to Laser Settings and Procedure Techniques to Optimize Outcomes with Femtosecond Lasers is a new, comprehensive text that presents a practical approach to optimizing laser settings and procedure techniques for performing LASIK, intracorneal ring segment placement, and other corneal procedures with currently available femtosecond lasers. Dr. Ella Faktorovich has provided detailed photographs and illustrations to demonstrate the techniques for optimizing procedure outcomes. The author guides you step-by-step through common procedures while providing a detailed approach to managing and preventing possible complications. Topics covered include: • Strategies for centration • Decreasing the incidence of opaque bubble layer formation ...
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Femtosecond Laser Pulses: Principles and Experiments (Advanced Texts in Physics)
by Claude Rulliere (Editor)
From the 1st editon: This smooth introduction for advanced undergraduate students starts with the fundamentals of lasers and pulsed optics. Thus prepared, the student learns how to generate short and ultrashort laser pulses, how to manipulate them, and how to measure them. Finally, spectroscopic implications are discussed. This rounded text gives the student an up-to-date introduction to one of the most exciting fields in laser physics. The 2nd edition will be completely revised, and will include two new chapters entitled "Coherent Control and Related Femtochemistry" and "Towards Attosecond and High Order Harmonics Generation"
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Active Glass for Photonic Devices Photoinduced Structures and Their Application
by Springer
This book deals with glass for high-tech applications in optoelectronic devices, focusing on new topics of fundamental importance in the application of active glasses in photonic devices. Most of the reports deal with glasses under action of higher electromagnetic fields, such as a femtosecond laser. Topics include manufacturing of the glass, analysis of induced structures in glasses, and some functional devices using active glasses
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Femtosecond Technology for Technical and Medical Applications
by Friedrich Dausinger (Editor), Friedemann Lichtner (Editor), Holger Lubatschowski (Editor)
Femtosecond technology, with its ultrashort light pulses, forms an innovative laser technology which can be used for multiple technical applications. The book gives a comprehensive overview of the principles and applications of femtosecond lasers, especially applied to medicine and to production technology. The principles and features of such femtosecond technology will be described. The lasers, systems and technologies that are required in these potential fields of application are investigated. The advantages and problems of ultrashort laser pulses are discussed in more detail in the context of applications in the micro-machining of technical materials such as drilling, surface structuring and cutting, in medical use like dental, ophthalmologic, neurological and otolaryngological...
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Theoretical Femtosecond Physics: Atoms and Molecules in Strong Laser Fields (Springer Series on Atomic, Optical, and Plasma Physics)
by F. Grossmann (Author)
Theoretical femtosecond physics is a new field of research. Theoretical investigations of atoms and molecules interacting with pulsed or continuous wave lasers of up to atomic field strengths are leading to an understanding of many challenging experimental discoveries. Laser-Matter interaction is treated on a nonperturbative level in the book using approximate and numerical solutions of the time-dependent Schrödinger equation. The light field is treated classically. Physical phenomena, ranging from ionization of atoms to the ionization and dissociation of molecules and the control of chemical reactions are presented and discussed. Theoretical background for experiments with strong and short laser pulses is given. Several exercises are included in the main text. Some detailed...
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Femtosecond Laser Filamentation (Springer Series on Atomic, Optical, and Plasma Physics)
by See Leang Chin (Author)
When a powerful femtosecond laser pulse propagates in an optical medium, self-focusing occurs. This book reviews the current up-to-date understanding of the physics of propagation leading to the self-transformation of the laser pulse into a white light laser pulse during self-focusing and filamentation. The physics of multiple filamentation and competition will be discussed. Its capability to melting glasses inside the filaments is observed which explains the physics of wave guide writing. Its potential applications in atmospheric sensing and material processing together with possible future challenges in the interaction of such self-transformed white light laser pulses with atoms and molecules will be treated. Nonlinear optics such as third harmonic generation in the filaments with...
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High-Power and Femtosecond Lasers: Properties, Materials and Applications (Lasers and Electro-Optics Research and Technology)
by Paul-henri Barret (Editor), Michael Palmer (Editor)
There has been a remarkable upsurge in the importance of high power lasers in the past decade. This book presents an overall survey of recent advances in high peak power solid lasers and reviews recent results in the interaction of high power laser pulses with various dielectric materials containing metal nanoparticles. This book also presents the basics as well as the theory of a single crystal photo-elastic modulator and a consideration of modern approaches to the synthesis of diffractive optical elements for technological IR-laser beams focusing. During ultrafast laser interaction with metal, the electrons and lattices are not in equilibrium. This book presents various two-temperature models that can be used to describe the non-equilibrium heat transfer as well as the results of...
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Femtosecond Laser Spectroscopy
by Peter Hannaford (Editor)
With recent major breakthroughs in ultrafast laser technology and femtosecond nonlinear spectroscopic techiques, Femtosecond Laser Spectroscopy is currently a burgeoning field in many branches of science, including physics, chemistry, biology, and materials science. There is an urgent need for researchers and postgraduate students to have a volume which includes the major research efforts currently in practice around the world and all under one cover.
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Optics of Femtosecond Laser Pulses
by Akhmanov (Author), V.A. Vysloukh (Author), A.S. Chirkin (Author)
"Blurb & Contents" The wave optics of ultrashort pulses--an area experiencing rapid growth--is closely scrutinized in this completely up-to-date survey, which emphasizes new problems connected with the propagation of the shortest possible pulses. You'll find a presentation of the principles of the Fourier optics of short wave packets propagating in linear dispersive media. Discusses the development of femtosecond laser systems along with the feasibility of controlling pulse shape. Contents: Short Optical Pulses in Linear Dispersive Media. Self-action of Optical Pulses; Self-modulation, Self-compression, Solitons, and Instabilities. Parametric Interactions and Coherent Scattering of Femtosecond Pulses. Fast Phase Control. Compression and Shaping of Optical Pulses. Optical Solitons....
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Density Matrix Method and Femtosecond Processes (World Scientific Lecture and Course Notes in Chemistry)
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This book originates from lectures given at Shandong University and Nanjing University and the special topics course offered at Arizona State University. It is prepared at a level intended for chemistry and physics graduate students.
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