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New technique improves outcome for living donor liver transplants
March 19, 2008
The University of Alberta Hospital (UAH) is one of only a few centers in Canada that perform living donor liver transplantation, a surgical procedure developed in the late 1980s that expands the organ donor pool. About 80 liver transplants are done a year in Alberta, 10 of those being living-donor. All potential liver transplant donors are assessed based on considerations such as the size and composition of the liver and vascular and bile duct anatomy. Thanks to a review paper done at the University of Alberta radiologists at the University of Alberta Hospital are now using CT (Computed Tomography) imaging for living-donor liver transplantation. This technique shows relevant liver anatomy and, in particular, enhances high resolution imaging of the vital bile duct anatomy.
"CT scans provide a clear image of the important ducts we need to see," said Dr. Gavin Low, a clinical fellow in the University of Alberta's Faculty of Medicine and Dentistry and author of a recent study describing this process. In the past radiologists have only been using an MRI to scan possible donors for bile duct anatomy, but Low said that, "By using CT imaging the results are much more accurate and reliable for the surgeons."
Right now possible donors are screened with both MRI and CT scans but Low says the hope is to one day only use CT imaging; adding, "All-in-one imaging will speed up the process and make living-donor evaluation more convenient for potential donors."
As many as four patients are evaluated by CT imaging every month.
University of Alberta
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Related Liver Transplantation Current Events and Liver Transplantation News Articles Liver Transplantation Current Events and Liver Transplantation News RSS The use of stem cells in regenerative medicine may also be detrimental for health The use of stem cells in regenerative medicine is not always beneficial for human health, it may even be harmful according to a work done by the University of Granada and University of León. Scientists have demonstrated that transplantation of human mononuclear cells isolated from umbilical cord blood exerted a deleterious effect in rats with liver cirrhosis.
UF scientists discover new explanation for controversial old patient-care technique You might not know what it's called, but if you've had general anesthesia before surgery, especially after an accident, it is likely you have received Sellick's maneuver.
How to identify early graft dysfunction preoperatively? Small-for-size graft dysfunction (SFSGD) following living-related liver transplantation (LRLT) is characterized by early graft dysfunction (EGD) when the graft-to-recipient body weight ratio (GRBWR) is below 0.8%.
Medication effective for acute liver failure in early stages of disease The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found.
Prompt diagnosis of ear infections can improve outcome for organ transplant recipients Organ transplant recipients benefit significantly when they are monitored and receive prompt diagnosis and treatment for otitis media, a common inner ear infection.
Evaluation of standard liver volume formula for Chinese adults Living donor liver transplantation (LDLT) has been used to alleviate the shortage of available liver donors. Accurate estimation of the standard liver volume (SLV) of the living donor and recipient is crucial.
Women, blacks, Medicare recipients less likely to be evaluated for liver transplantation Patient race, gender and insurance status influence decisions about who will go on to receive liver transplants, according to a University of Pittsburgh School of Medicine study.
Lower tacrolimus doses is suitable for living donor liver transplantation with small-for-size graft Several studies have shown that living donor liver transplant (LDLT) recipients required smaller doses of tacrolimus compared with deceased donor liver transplant (DDLT) patients, which indicated that liver regeneration could affect the metabolism of tacrolimus in LDLT.
Sequential TACE and cryosurgery can improve survival times for patients with HCC? Hepatocellular carcinoma (HCC)--a liver cancer--is recognized as one of the most common cancers in the world that disproportionately affects Southeast Asians and Africans.
Metabolic bone disease in cirrhosis patients Long-standing liver disease has long been recognized to result in fragile bones with increased risk of fractures. In various international studies, the overall incidence has varied from 11% to 48%, with a fracture rate of 3%-44%. More Liver Transplantation Current Events and Liver Transplantation News Articles
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Transplantation of the Liver
by Ronald W. Busuttil (Editor), Goran B. Klintmalm (Editor)
Spearheaded by two of the world's preeminent experts in liver surgery, the new edition of this landmark masterwork encompasses all of today's best knowledge in the field. It provides detailed discussions of everything from pathophysiology and patient and donor selection...through transplantation anesthesia and full range of operative procedures...to immunosuppression, postoperative care, and ethical issues. The result is an ideal single source for authoritative, up-to-the-minute guidance on every imaginable aspect of liver transplantation.
Discusses the background and available management options for each hepatic disease entity. Addresses anesthesia for liver transplantation"oa crucial aspect of successful surgery that is often neglected in other sources. Provides...
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Medical Care of the Liver Transplant Patient: Total Pre-, Intra- and Post-Operative Management
by Paul G Killenberg (Editor), Pierre-Alain Clavien (Editor)
Medical Care of the Liver Transplant Patient looks at monitoring and maintaining the health of organ recipients and donors, pre, during and post-operatively. There are twenty-nine chapters containing practical advice on total patient management. They are arranged into 8 sections and follow the stages of transplantation from first indication and selection of potential recipient, through to acute recovery, long-term follow-up and continued health.
In this edition there are new chapters on special considerations in liver transplant patients such as viral hepatitis, alcoholic liver disease and live donor liver transplantation. It also contains the very latest information concerning complications and recurring problems after transplantation. Another new chapter considers fresh...
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Liver Transplantation: Rejection, Therapy and Post-operative Complications
by Kirsten H. Knudsen (Editor)
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with a healthy liver allograft. The most commonly used technique is orthotopic transplantation, in which the native liver is removed and the donor organ is placed in the same anatomic location as the original liver. Liver transplantation nowadays is a well accepted treatment option for end-stage liver disease and acute liver failure. This book presents the latest research from around the world in this field.
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A.H.P.B.A- 2005 Surgical Spring Week /DVD:19
Also With: American Hepato-Pancreato-Biliary Association (Host)
A.H.P.B.A- 2005 Surgical Spring Week /DVD:19
SYMPOSIUM: Anesthesia challenges in liver transplantation - Problem based learning discussion (PBLD) . Perioperative management of OLT in a patient with elevated ICP due to fulminate hepatic failure, Porto-pulmonary hypertension in a patient for OLT-evaluation, contraindications and treatment - Dr. Alexandru Gottlieb (USA) Dr. Brian M. Parker (USA) / Dr. Michael A. E. Ramsay (USA)
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Advances in Digestive Disease CD-ROM
by AGA Institute Press
Editor
Colin W. Howden, MD, AGAF
Associate Editors
Alan L. Buchman, MD, MSPH, AGAF
Steven L. Flamm, MD
Ikuo Hirano, MD
Michael P. Jones, MD
Looking to get up to speed on recent advances in gastroenterology and hepatology?
This peer-reviewed reference tool offers guidance to those involved in the clinical aspects of gastroenterology. Clinicians will find the information they need to navigate some of the most difficult GI diagnoses. Twenty-one full-color chapters by 37 clinician and industry experts provide pertinent reviews of topics divided into five main categories: upper GI, holistic issues, lower GI, hepatology and GI cancer, making this a must-have for every clinician.
In every chapter, quick-reference tables and charts are included to offer the user clarity and a better...
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Liver Transplantation: Challenging Controversies and Topics (Clinical Gastroenterology)
by Gregory T. Everson (Editor), James F. Trotter (Editor)
The field of liver transplantation is young, evolving, dynamic, and issues and decisions are often controversial, thus a text with a different focus is required, one that highlights controversy and challenges dogma. In Liver Transplantation: Challenging Controversies and Topics a useful set of chapters have been created that will take the reader step-by-step through key areas of controversy in the field of liver transplantation. The authors have tried to anticipate questions, define key issues, and provide options for resolving or approaching areas of uncertainty. The topics covered in this book impact our understanding and management of immunosuppressant, viral hepatitis, nonalcoholic fatty liver disease, organ allocation, regional differences in rates of transplantation, and...
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100 Q&A About Liver Transplantation: A Lahey Clinic Guide (100 Questions & Answers about)
by Fredric D. Gordon (Author)
Whether you or a loved one is contemplating liver transplantation, on the waiting list for liver transplantation, or are a transplant recipient, the options and information about this surgery can be overwhelming. This invaluable resource offers the guidance and advice you need. Written by a prominent physician, this book gives you authoritative, practical answers to your pre- and post-surgery questions about indications, evaluation, medications and side effects, living donor transplantation, and much more.
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A.H.P.B.A- 2005 Surgical Spring Week /DVD:14
Also With: American Hepato-Pancreato- Biliary Association (Host)
A.H.P.B.A- 2005 Surgical Spring Week /DVD:14
FREE PAPER Session: Liver transplantation . Protection from cold ischemia-induced apoptosis despite cytoplasmic ATP depletion by purinergic receptor antagonism - Dr. Chris Anderson (USA) . Short-term administration of (-)- Epigallocatechin gallate reduces hepatic steatosis and protects against hepatic ischemia / reperfusion injury in steatotic mice - Dr. Ryan Fiorini (USA) . One liver for two - liver regeneration in living donors and recipients - Dr. Burkhardt Ringe (USA) . Long-term follow-up of living donor liver transplantation - 12 years of experience - Dr. Sukru Emre (USA) . Predicting post-transplant graft survival in liver transplant recipients using perioperative characteristics under the new MELD system - Dr. Derek Moore (USA) ....
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The Gift of Life 2: Surviving the Waiting List and Liver Transplantation
by Parichehr Yomtoob; Laura Yomtoob; Deborah Wepler (Author)
Seventeen years after a successful liver transplant, David Yomtoob once again found himself fighting for his life against the backdrop of organ waiting lists and a valiant team of doctors and nurses working to keep him alive while he waited. Only 12 years old when his first liver failed with advanced Wilson’s disease, David was among the first to receive a transplanted liver in 1981. He led a normal life when suddenly, 17 years later, that liver began to fail. Three years and four transplants centers later, David arrived home again with a new liver, but only after he and his family had been tested by the challenges faced by every transplant family on the waiting list. According to the United Network for Organ Sharing (UNOS), nearly 90,000 people are waiting for donated...
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Liver Transplantation (Landes Bioscience Medical Handbook (Vademecum))
by Michael Lucey (Author)
Univ. of Wisconsin, Madison. Pocket-sized handbook for those involved in the care and management of patients who have undergone a liver transplant. Provides an overview of liver transplantation, allograft immune response, immunosuppression after transplantation, graft dysfunction, and pediatric transplantation. Wire-spiral binding.
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