 |
|
LDL particle measurement by NMR recognized by ADA, ACC
March 31, 2008The American Diabetes Association (ADA) and the American College of Cardiology (ACC) issued a consensus statement today that states the measurement of LDL particle number by nuclear magnetic resonance (NMR) is one of the more accurate ways to evaluate cardiometabolic risk (CMR). The study, published in the April issue of Diabetes Care, reinforces that LDL cholesterol may not be the best way to quantify a patient's risk for cardiovascular disease (CVD).
Cardiometabolic Risk (CMR) is associated with Type 2 Diabetes and CVD - obesity, insulin resistance, hyperglycemia and hypertension are risk factors that often cluster together. ApoB and LDL particle concentration appear to be more closely associated with these markers of CMR than LDL cholesterol or non-HDL cholesterol. Subsequently, lipoprotein abnormalities are commonly found in patients with CMR. According to the consensus statement, ApoB and LDL particle number by NMR appear to be more discriminating measures of the adequacy of LDL lowering therapies than are traditional LDL and HDL cholesterol measures.
"Several studies have shown that LDL cholesterol (LDL-C) poorly characterizes lipid abnormalities in patients with cardiometabolic risk," says Robert S. Rosenson, MD, Director of Lipoprotein Disorders and Clinical Atherosclerosis Research, University of Michigan School of Medicine and presenter at the consensus panel meeting. "Additionally, LDL-P concentrations, compared to LDL-C and non HDL-C, have been shown to be stronger predictors of cardiovascular risk."
The NMR LipoProfile® test, developed by LipoScience, Inc., is the only test that quantifies LDL particle number (LDL-P) using Nuclear Magnetic Resonance. LDL particle information is used by clinicians to monitor the effect of lipid altering interventions, such as statins, in the management of a patient's cardiovascular health by lowering LDL particle number (LDL-P).
Studies show that low concentrations of LDL particles are associated with fewer cardiovascular disease related events than equivalently low levels of LDL cholesterol; data most recently published from the Framingham Offspring study in December 2007.1
"This consensus statement further demonstrates the critical role that the NMR LipoProfile® test can play for the millions of people with diabetes or cardiovascular disease risk," says Rick Brajer, Chief Executive Officer and President, LipoScience, Inc. "Measuring LDL particle number by NMR presents physicians and patients with the opportunity to better manage cardiometabolic risk."
Dorland Global Public Relations
The NMR LipoProfile® test, developed by LipoScience, Inc., is the only test that quantifies LDL particle number (LDL-P) using Nuclear Magnetic Resonance. LDL particle information is used by clinicians to monitor the effect of lipid altering interventions, such as statins, in the management of a patient's cardiovascular health by lowering LDL particle number (LDL-P).
Studies show that low concentrations of LDL particles are associated with fewer cardiovascular disease related events than equivalently low levels of LDL cholesterol; data most recently published from the Framingham Offspring study in December 2007.1
"This consensus statement further demonstrates the critical role that the NMR LipoProfile® test can play for the millions of people with diabetes or cardiovascular disease risk," says Rick Brajer, Chief Executive Officer and President, LipoScience, Inc. "Measuring LDL particle number by NMR presents physicians and patients with the opportunity to better manage cardiometabolic risk."
Dorland Global Public Relations
Community-based diabetes prevention program shows promise
With over 60 million Americans diagnosed with prediabetes, putting them at increased risk for diabetes, cardiovascular events and other obesity-related ailments, finding ways to help large populations avoid these complications is an important initiative.
Drinking in excess associated with increased risk for metabolic syndrome
Those who drink in excess of the U.S. Dietary Guidelines (i.e., men who usually drink more than two drinks per day or women who usually drink more than one drink per day) or those who binge drink are at increased risk for the metabolic syndrome, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
Researcher predicts paradigm shift in heart disease treatment
As the obesity epidemic grows in the United States, the medical community is faced with the significant challenge of properly treating patients before complications such as heart disease arise.
More Cardiometabolic Risk Current Events and Cardiometabolic Risk News Articles
 |
Atlas of Cardiometabolic Risk (Atlas Of...) by William T. Cefalu (Author), Christopher P. Cannon (Author) The first atlas devoted specifically to cardiometabolic risk, this book provides a concise, visual primer on the pathophysiology, epidemiology, diagnosis, treatment, and clinical and radiologic features of this disorder. Describing recent care strategies and current practices in patient assessment, this source will allow clinicians to accurately identify and treat those patients at increased risk for metabolic syndrome, cardiovascular disease, and diabetes. Authored by leading clinical researchers in the field of cardiometabolic risk, this guide: offers step-by-step diagnostic and therapeutic protocols contains clinical photographs, radiographic images, schematic illustrations, algorithms, and tables summarizing key information analyzes the biochemical, physiologic, and... |
 |
Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk by Jean-Pierre Despres (Editor), Vincenzo Di Marzo (Editor) This internationally renowned author team provides a unique and thorough analysis and distillation of the endocannabinoid system and its relationship to abdominal obesity, diabetes, and cardiovascular disease. The endocannabinoid system (ECS) plays an important role in cardiometabolic risk, as well as modulating energy balance, feeding behavior, hepatic lipogenesis, and perhaps glucose homeostasis. Evidence suggests that the ECS is overactive in human obesity and dyslipidemia. Critical to the management of cardiometabolic risk, this new, timely book provides practical overviews and management guidance on many important topics, including:
|
|
Prospective validation in identical Turkish cohort of two metabolic syndrome definitions for predicting cardiometabolic risk and selection of most appropriate ... of Cardiology (Anadolu Kardiyoloji Dergisi) by Altan Onat (Author), Gulay Hergenc (Author), Gunay Can (Author) This digital document is an article from The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi), published by Thomson Gale on March 1, 2007. The length of the article is 5790 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Prospective validation in identical Turkish cohort of two metabolic syndrome definitions for predicting cardiometabolic risk and selection of most appropriate definition/Iki metabolik sendrom taniminin kardiyometabolik risk ongorusunun ayni kohortta prospektif yolla degerlendirilmesi ve halkimiz icin en uygun tanimin secilmesi.(Original... | |
 |
Diet and Cardiometabolic Risk: An overview and in-depth studies of the Metabolic Syndrome by Per Sjögren (Author) Over the past decade, the metabolic syndrome has increased dramatically in the population and its contribution to the development of cardiovascular disease has grown in parallel. This is an ongoing situation, and as a consequence, metabolic abnormalities encompassed by the metabolic syndrome, such as dyslipidemia, obesity and insulin resistance, constitute a major threat to public health. Although the metabolic syndrome has its limitations as a clinical diagnosis, there is a need to improve our understanding of its aetiological link to cardiovascular disease in order to identify possible interventions. This book provides a general overview, including strengths and weaknesses, of the metabolic syndrome and its link to cardiovascular disease. The book also... |
|
Managing Cardiometabolic Risk: Abdominal Obesity and Weight-related Disease by Henry Purcell (Editor) This book brings together leading authorities on cardiovascular disease to present an integrated overview of the factors that combine to increase patients' global cardiometabolic risk and expose them to a greater probability of adverse outcomes, including stroke, myocardial infarction, and cancer.Weight gain and obesity are now recognised as primary risk factors for diabetes and heart disease; describing relationships between obesity, type 2 diabetes and CV risk factors such as hypertension and dyslipidaemias, this new work explains how current demographic trends in diet and lifestyle choices lead to cumulative increases in risk, and explores the strategies by which these risks can be managed and reduced.It is the first book to present an integrated overview of risk factors in... | |
|
Importance of metabolic syndrome definitions in prediction of cardiometabolic risk/Prospective validation in identical Turkish cohort of two metabolic ... of Cardiology (Anadolu Kardiyoloji Dergisi) by Fulden Sarac (Author), Altan Onat (Author) This digital document is an article from The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi), published by Thomson Gale on June 1, 2007. The length of the article is 812 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Importance of metabolic syndrome definitions in prediction of cardiometabolic risk/Prospective validation in identical Turkish cohort of two metabolic syndrome definitions for predicting cardiometabolic risk and selection of most appropriate definition.(Letter to the Editor/Editore Mektup)(Letter to the editor)(Clinical report) Author: Fulden... | |
|
On the criteria of metabolic syndrome in predicting incident coronary disease and diabetes in Turkish adults/Abdominal obesity and cardiometabolic risk/Halkimizda ... of Cardiology (Anadolu Kardiyoloji Dergisi) by Altan Onat ve Gulay Hergenc (Author) This digital document is an article from The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi), published by Thomson Gale on June 1, 2007. The length of the article is 909 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: On the criteria of metabolic syndrome in predicting incident coronary disease and diabetes in Turkish adults/Abdominal obesity and cardiometabolic risk/Halkimizda yeni gelisen koroner hastalik ve diyabet riski ongorusunde metabolik sendrom kriterleri hakkinda/abdominal obezite ve kardiyometabolik risk.(Letter to the Editor/Editore Mektup)(Letter to... | |
|
Abdominal obesity and cardiometabolic risk/Abdominal obezite ve kardiyometabolik risk.(Editorial Comment/Editoryel Yorum): An article from: The Anatolian ... of Cardiology (Anadolu Kardiyoloji Dergisi) by Ahmet Temizhan (Author) This digital document is an article from The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi), published by Thomson Gale on March 1, 2007. The length of the article is 1871 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Abdominal obesity and cardiometabolic risk/Abdominal obezite ve kardiyometabolik risk.(Editorial Comment/Editoryel Yorum) Author: Ahmet Temizhan Publication: The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi) (Magazine/Journal) Date: March 1, 2007 Publisher: Thomson Gale Volume: 7 Issue: 1 Page:... | |
 |
Annual Review of Diabetes 2009 by American Diabetes Association (ADA) (Author) The most educational, informative, and at-times, controversial articles published in the last year |
 |
Visceral Obesity and Cardiometabolic Risk - A Handbook for Clinicians by Jean-Pierre Despres (Author) |
| © 2009 BrightSurf.com |