Vive the vole!April 01, 2008The gathering of data for research involving an animal usually involves invasive procedures or death for the experimental animals. But critical data may now be collected through a nonlethal procedure, according to a new paper for the forthcoming issue of Physiological and Biochemical Zoology. In the paper "Dual-Energy X-Ray Absorbtiometry (DXA) Can Accurately and Non-Destructively Measure the Body Composition of Small, Free-Living Rodents," Kalb Stevenson and Dr. Ian G. van Tets reveal that they have discovered that they can take a wide range of measurements accurately with a portable DXA device. These body composition measurements in small rodents-water, protein, minerals, lean, and fat-are critical for dietary and environmental research. Previous measurements taken in the field, though not lethal, relied on length and body mass calculations, which are often inaccurate; methods used on laboratory animals are often lethal, precluding longitudinal research. Differing methods used in fieldwork and in the laboratory limited scientific collaboration. Legal and/or ethical barriers against invasive research on endangered species further hampered crucial studies. "We needed a way to accurately and consistently measure the body condition of small mammals recaptured at different times of the year and could not do so using traditional means" said Dr. van Tets "so we decided to test whether DXA analysis could solve this problem". In their NSF-funded study of the northern redbacked vole (Clethrionomys rutilus), Stevenson and van Tets took a broad set of measurements accurately by employing DXA, using X-rays and mathematical formulas to noninvasively measure body content. Even transponder tags used to track the rodents in the wild did not interfere with their measurement of fat mass, lean mass, bone mineral content, bone mineral density, and fat-free mass. "DXA worked better than we expected" Stevenson said "The measurements were consistent with those obtained via chemical (proximate) analysis and required nothing more than the machine itself, a laptop, and a power source. As subjects are not harmed, we can use this technology to track changes in individual animals over time and already have DXA-based projects underway studying the effects of season and/or hibernation on the body composition of animals as diverse as voles, ground squirrels, and black bears." Portable DXA devices provide the opportunity for quick measurements in the field and the ability to take measurements over time, allowing researchers to account for environmental factors. And, finally, field researchers and laboratory researchers will be able to collaborate using comparable data, allowing an increased degree of scientific rigor in comparative physiological studies. University of Chicago Press Journals |
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| Related Body Composition Current Events and Body Composition News Articles Women at risk from vitamin A deficiency Almost half of UK women could be suffering from a lack of vitamin A due to a previously undiscovered genetic variation, scientists at Newcastle University have found. Redefining obesity's health risks The body mass index (BMI) has long been the yardstick in deciding who is at risk because of their weight. BMI is essentially a measure of density, identifying 'under-' and 'over-weight' risk groups. Postmenopausal women benefit from endurance training as much as younger women Marilyn Graham was 56 when she signed up for a grueling hour of cycling each morning for 12 weeks, occasionally decked out in a mask, a heart monitor and a bag of intravenous fluid and subjected to needle pricks to obtain blood samples. Large thighs protect against heart disease and early death Men and women whose thighs are less than 60cm in circumference have a higher risk of premature death and heart disease, according to research published on bmj.com today. Physical inactivity poses greatest health risk to Americans, research shows As many as 50 million Americans are living sedentary lives, putting them at increased risk of health problems and even early death, a leading expert in exercise science told the American Psychological Association today. Groundbreaking study shows exercise benefits leukemia patients One of the most bothersome symptoms of leukemia is extreme fatigue, and asking these patients to exercise doesn't sound like a way to help them feel better. New science review examines multiple health benefits of dairy foods Food prices rose by 5.5 percent in the past year and are expected to increase up to an additional 4 percent in 2009. Breastfeeding duration and weaning diet may shape child's body composition Variations in both milk feeding and in the weaning diet are linked to differences in growth and development, and they have independent influences on body composition in early childhood. Ben-Gurion U of the Negev study demonstrates link between appetite and elderly mortality A new study by a Ben-Gurion University of the Negev (BGU) researcher reveals a linkage between elderly people's appetite and mortality rates, with those who report impaired appetite more likely to die sooner. The cardiovascular benefits of daily exercise in school children are evident even after 1 year School children as young as 11 can benefit from a daily exercise programme in reducing their levels of several known risk factors for cardiovascular disease. An ongoing study, which began four years ago in the German city of Leipzig, shows already that children assigned to daily exercise lessons reduced their overall prevalence of obesity, improved their exercise capacity, increased their levels of HDL-cholesterol, and reduced their systolic blood pressure. More Body Composition Current Events and Body Composition News Articles |
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