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MRI changes breast cancer treatment choice; increases time to treatment
April 14, 2008More than a quarter of breast cancer patients who had an MRI examination before their initial surgical treatment had their treatment change, according to a study out of Yale University School of Medicine.
The study included 110 who had an MRI examination before treatment and 374 who did not undergo an MRI examination. "MRI prompted biopsy of 70 sites in 44 patients, said Carol Lee, MD, an author of the study, now at Memorial Sloan Kettering Cancer Center in NY. Sixteen additional sites of cancer were found in 13 (12%) women, she said.
Surgical treatment was changed in 31 (28%) cases, she added. Fifteen patients had mastectomy rather than lumpectomy. Six had more extensive lumpectomy and three had treatment for cancer that was detected in the opposite breast. "Seven others made a decision to have bilateral mastectomy after a suspicious finding was seen on MRI but before additional cancer was confirmed by a biopsy; it turned out that none had cancer in the contralateral breast" Dr. Lee noted. "While we can't show definitively that these women made the choice to have a mastectomy due to concerns generated by findings on the MR images, this remains a possibility, and patients and their doctors need to take this into consideration before deciding to have an MRI examination before treatment," Dr. Lee said.
Adding an MRI examination also delayed treatment. "The mean interval between diagnosis and definitive surgery in the group that had the MRI examination was 41 days compared to 27 days for the patients who did not undergo an MRI examination," she said.
"Breast MRI is a very useful tool for assessing extent of tumor in the breast, however, there are downsides that need to be taken into consideration," Dr. Lee emphasized.
American Roentgen Ray Society
Adding an MRI examination also delayed treatment. "The mean interval between diagnosis and definitive surgery in the group that had the MRI examination was 41 days compared to 27 days for the patients who did not undergo an MRI examination," she said.
"Breast MRI is a very useful tool for assessing extent of tumor in the breast, however, there are downsides that need to be taken into consideration," Dr. Lee emphasized.
American Roentgen Ray Society
Breast Cancer Treatment Current Events and Breast Cancer Treatment News RSSPenn studies point to strategies for reducing painful breast cancer drug side effects
Aromatase inhibitors, the same drugs that have buoyed long-term survival rates among breast cancer patients, also carry side effects including joint pain so severe that many patients discontinue these lifesaving medicines.
Study shows PET can measure effectiveness of novel breast cancer treatment
A new study published in the July issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) scans in mice can be used to determine whether a novel type of breast cancer treatment is working as intended.
Many breast cancer patients take high doses of antioxidants despite possible consequences
A new study finds that many women with breast cancer take antioxidant supplements while undergoing cancer treatment, even though the consequences of doing so are unknown.
Many breast cancer patients take high doses of antioxidants despite possible consequences
A new study finds that many women with breast cancer take antioxidant supplements while undergoing cancer treatment, even though the consequences of doing so are unknown.
Women 10 times more likely to do breast self-exams correctly with intervention, KP study finds
A brief intervention program - consisting of one counseling session and two follow-up phone calls - boosted by tenfold the number of women correctly performing breast self- exams.
High blood pressure linked to earlier death among African-American breast cancer patients
A study by researchers at the University of California, San Francisco has shown that hypertension, or high blood pressure, is a predictor of mortality among breast cancer patients, especially those who are African-American, and that hypertension accounts for approximately 30 percent of the survival disparity between African-American and white breast cancer patients.
New genomic test can personalize breast cancer treatment
A set of 50 genes can be used to reliably identify the four known types of breast cancer, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.
Progress made in understanding causes and treatment of endometriosis
Endometriosis is a poorly understood chronic disease characterized by infertility and chronic pelvic pain during intercourse. It affects between 5 to 10 million women in the U.S.
Obesity Increases Lymphedema Risk for Breast Cancer Survivors
Throughout the world, 10 million breast cancer survivors have a lifetime risk for developing lymphedema, a chronic condition that involves swelling of the limbs and impacts physical and psychosocial health.
Breast cancer treatment offers better outcome to women with implants
Women with early-stage breast cancer who have undergone breast augmentation may be treated successfully with a partial-breast radiation treatment called brachytherapy, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).
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