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3T MRI plays significant role in detecting prostate cancer, study says
April 14, 2008The use of MRI without endorectal coil can detect prostate cancer and provide undistorted images with diagnostic image quality and accurate tumor localization, according to a recent study conducted by researchers from The Ohio State University in Columbus, OH.
"The 3T MRI datasets were acquired without an endorectal coil and were used during robotic surgery," said Steffen Sammet, MD, PhD, lead author of the study. "Since the use of an endorectal coil leads to deformation of the prostate and potentially altered microcirculation, our goal was to assess the capability of detecting prostate cancer areas by dynamic contrast enhanced MRI without endorectal coil at 3T validated by correlation with surgical pathology," he said.
The study included 13 patients with prostate cancer who were scheduled for prostatectomy and were imaged on a 3T MRI. The researchers noted suspicious areas, tumor location, extracapsulation (the extent of the tumor outside the capsule of the prostate and is a associated with a unfavorable prognosis), and seminal vesicle involvement. Once this was complete, 3D reconstruction of the prostate, tumor neurovascular bundle and surrounding tissue was performed and used as an intra-operative "roadmap".
According to the study, cancer was correctly localized in 11 of the 13 patients. There was an agreement with pathology in 10 of the 13 patients regarding extracapsulation and 11 of 13 regarding seminal vesicle involvement. The study showed that 3D reconstruction was useful for the surgical roadmap in all 13 cases.
"High field MRI enables the acquisition of undistorted prostate images without endorectal coil. The high signal to noise ratio and the image quality of the prostate and the surrounding tissue may, in the future, allow us to detect prostate cancer at an earlier stage," said Dr. Sammet.
American Roentgen Ray Society
According to the study, cancer was correctly localized in 11 of the 13 patients. There was an agreement with pathology in 10 of the 13 patients regarding extracapsulation and 11 of 13 regarding seminal vesicle involvement. The study showed that 3D reconstruction was useful for the surgical roadmap in all 13 cases.
"High field MRI enables the acquisition of undistorted prostate images without endorectal coil. The high signal to noise ratio and the image quality of the prostate and the surrounding tissue may, in the future, allow us to detect prostate cancer at an earlier stage," said Dr. Sammet.
American Roentgen Ray Society
Prostate Cancer Current Events and Prostate Cancer News RSSCarnegie Mellon researchers link health-care debate to risk of dying in US and Europe
The current health care debate in the United States is complicated. Trade-offs between heath care expenditures, lifestyle choices and life expectancy have been suggested but seldom clearly demonstrated.
New finding suggests prostate biopsy is not always necessary
Researchers at Wake Forest University School of Medicine and the University of Wisconsin-Madison have discovered that some elevated prostate-specific antigen (PSA) levels in men may be caused by a hormone normally occurring in the body, and are not necessarily a predictor of the need for a prostate biopsy.
Does prostate-specific antigen velocity help in early detection prostate cancer?
The November issue of European Urology, the official journal of the European Association of Urology, features an article focussing on prostate specific antigen (PSA) velocity and early cancer detection. It has been suggested that changes in PSA over time aid prostate cancer detection.
New Synthetic Molecules Trigger Immune Response to HIV and Prostate Cancer
Researchers at Yale University have developed synthetic molecules capable of enhancing the body's immune response to HIV and HIV-infected cells, as well as to prostate cancer cells. Their findings, published online in the Journal of the American Chemical Society, could lead to novel therapeutic approaches for these diseases.
Chemo-radiation before prostate removal may prevent cancer recurrence
Researchers in the Oregon Health & Science University Knight Cancer Institute and the Portland Veterans Affairs Medical Center have found a combination of radiation therapy and chemotherapy given before prostate removal is safe and may have the potential to reduce cancer recurrence and improve patient survival.
Blood vessels might predict prostate cancer behavior
A diagnosis of prostate cancer raises the question for patients and their physicians as to how the tumor will behave. Will it grow quickly and aggressively and require continuous treatment, or slowly, allowing therapy and its risks to be safely delayed?
Short-term hormone therapy and intermediate dose radiation increases survivial for early stage prostate cancer
Short-term hormone therapy given prior to and during intermediate dose radiation treatment for men with early stage prostate cancer increases their chance of living longer, compared to those who receive the same radiation alone.
Task force develops new radiation guidelines for brachytherapy
Radiation dose delivered to the prostate and nearby organs in every brachytherapy procedure should be carefully analyzed using post-implant CT or MRI and uniformly documented in every patient.
1 disease, not 1 demographic
The Asian continent has nearly four billion people living in 47 different countries, and each of these groups has their own unique set of health issues. But when they come to the United States, they're often lumped into one large demographic: "Asian/Pacific Islander."
Cancer survivors may not be getting the help they need to stop smoking
More than a quarter of cancer survivors who still smoke have not been advised to quit smoking by their health care providers in the last year, according to a study published by researchers at Fox Chase Cancer Center in the current issue of the Journal of General Internal Medicine.
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Dr. Patrick Walsh's Guide to Surviving Prostate Cancer, Second Edition by Patrick C. Walsh (Author), Janet Farrar Worthington (Author) EVERY MAN NEEDS THIS BOOK! Each year, more than 200,00 American men are diagnosed with prostate cancer. The good news is that more men are being cured of this disease than ever before. Now in a revised second edition, this lifesaving guide by Dr. Patrick Walsh and ard-winning science writer Janet Farrar Worthington offers a message of hope to every man facing this illness. Prostate cancer is a different disease in every man--which means that the right treatment varies for each man. Giving you a second opinion from the world's top experts in surgery, pathology, urology, and radiation and medical oncology, this book helps you determine the best plan for you. Learn:What causes prostate cancer--your risk factors, including heredity, diet, and environmentHow some simple changes in your... |
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