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6-month follow-up diagnostic mammograms recommended for women with probably benign lesions
May 09, 2008Radiologists can, with confidence, recommend a six-month follow-up diagnostic mammogram rather than an immediate biopsy for patients with "probably benign" breast lesions, a new study emphasizes.
The study found that six-month short-interval follow-up examinations had an 83% sensitivity, which is similar to the sensitivity of other diagnostic mammograms, said Erin J. Aiello Bowles, MPH, lead author of the study from the Group Health Center for Health Studies. High sensitivity means identifying a high proportion of "true positives" (actual cancer cases) and a low proportion of "false negatives" (cases mistakenly deemed benign).
The study included 45,007 initial short-interval follow-up mammograms. "Short-interval follow-up mammograms are done to monitor for changes in 'probably benign' breast lesions (findings seen on mammograms that have a very low probability of being cancer). Because the probability of cancer is so low, we don't want to put the patient through an unnecessary biopsy, which is an invasive procedure that increases both patient anxiety and medical costs," said Aiello Bowles. "At the same time, we want to closely monitor these patients, because changes in 'probably benign' lesions occasionally mean cancer, and we want to detect the cancers as early as possible," she said. In the study, 360 women with "probably benign" lesions were diagnosed with breast cancer within six months; and 506 women were diagnosed with cancer within 12 months (altogether about one in 100 of the "probably benign" lesions), Aiello Bowles said.
"The Breast Imaging-Reporting and Data System (BI-RADS) recommends that women with a BI-RADS category 3 (probably benign) lesion get a six-month diagnostic mammogram, with follow-up continued for the next two to three years until long-term stability is demonstrated," said Dr. Edward Sickles, a coauthor and radiologist involved in the study from the University of California San Francisco. "This study emphasizes that radiologists and patients need to follow that recommendation," he said.
American Roentgen Ray Society
"The Breast Imaging-Reporting and Data System (BI-RADS) recommends that women with a BI-RADS category 3 (probably benign) lesion get a six-month diagnostic mammogram, with follow-up continued for the next two to three years until long-term stability is demonstrated," said Dr. Edward Sickles, a coauthor and radiologist involved in the study from the University of California San Francisco. "This study emphasizes that radiologists and patients need to follow that recommendation," he said.
American Roentgen Ray Society
Mammograms Current Events and Mammograms News RSSScientists uncover new key to the puzzle of hormone therapy and breast cancer
The use of postmenopausal hormone therapy has decreased over time in the United States, which researchers suggest may play a key role in the declining rate of atypical ductal hyperplasia, a known risk factor for breast cancer.
Researcher: 'Optical biopsy' for breast cancer increasingly accurate
But women may not have to endure the medical costs, stress and potential complications that accompany such invasive biopsies forever. A University of Florida biomedical engineering researcher is making progress on an "optical biopsy" that has the potential to determine whether growths are cancerous without ever puncturing the skin.
M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers
Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers.
Study finds delay in follow-up among African-American women receiving abnormal breast finding
A new analysis has identified a significant delay in follow-up times among African-American women after the finding of a suspicious breast abnormality.
Researchers fine-tune Diffuse Optical Tomography for breast cancer screening
Clemson University researchers in collaboration with researchers at the University of Bremen, Germany, are working to make the physical pain and discomfort of mammograms a thing of the past, while allowing for diagnostic imaging eventually to be done in a home setting.
Researchers believe hormone therapy should not be stopped prior to mammograms
Researchers from Boston University School of Medicine (BUSM) are recommending that menopausal women on hormone therapy (HT) continue their treatment prior to having their annual mammogram screenings.
Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
A study published in this week's online issue of Nature Biotechnology, demonstrates a unique and highly sensitive method for detecting methylation-associated cancers.
Cancers set to 'explode' in Latino/a populations, expert says
he Latino/a population in the United States is expected to triple by 2050, according to projections from the U.S. Census Bureau. And along with that growth, says University of Illinois professor Lydia Buki, will come a rise in the number of individuals from that population who are diagnosed with cancer.
Reminder program dramatically increases mammography rates, Kaiser Permanente study finds
A reminder program aimed at screening for breast cancer when it is most treatable boosted mammography rates by more than 17 percentage points.
I-SPY trial offers key insights into locally advanced breast cancer
Scientists are reporting two findings that could influence the way researchers screen for, treat and assess prognosis for women with locally advanced breast cancer, an aggressive form of the disease.
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Thanks for the Mammogram!: Fighting Cancer with Faith, Hope and a Healthy Dose of Laughter by Laura Jensen, Walker (Author) When Laura Jensen Walker was diagnosed with breast cancer on her first wedding anniversary, she found humor to be healing in the midst of terrifying circumstances. In Thanks for the Mammogram! she recounts the highs and lows-from discovering that "bald is beautiful" to navigating the world of saline breast implants. Infused with strength and dignity, this book shows women confronting the disease, and those who love them, that faith, hope, and a healthy dose of laughter can make all the difference. Now available for the first time in trade paper with an updated look, Thanks for the Mammogram! is poised to impact a whole new generation of women coping with breast cancer. |
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