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Fibroids common, but women have options
May 19, 2008Small fibroids located just beneath the lining of the uterus (submucosal) are more likely to move to the endometrial cavity after uterine artery embolization (UAE) but usually don't cause major complications, according to a new study.
The study included 49 patients with 140 fibroids who underwent an MRI examination before and after UAE. The study found that 39 of these were submucosal. Of these, 33% migrated to the endometrial cavity after UAE, said Sachit Verma, MD, lead author of the study. "At the beginning of our study, we suspected that all submucosal fibroids became endocavitary following UAE irrespective of their area of contact with the endometrium (ID ratio)," said Dr. Verma. "By further analyzing our results we realized that submucosal fibroids with an ID ratio greater than 0.55 at pre-procedural MRI have a higher risk of becoming endocavitary following UAE," he said
The majority of these fibroids are expelled spontaneously without significant symptoms, Dr. Verma said. However it is good to know if patients are at higher risk of this situation occurring so they can be better counseled regarding risk of post procedural complications and symptoms such as menorrhagia, acute pelvic pain or persistent vaginal discharge, he said. Patients may also choose an alternative treatment option, such as hysteroscopic resection and/or myomectomy, said Dr. Verma.
In a recent commentary written in conjunction with the study, by Fred Burbank, MD adds patients contemplating UAE should anticipate that fibroids bordering on or inside the uterine cavity may require cervical dilatation or hysteroscopic resection for removal. The addition of either of these gynecology procedures shouldn't necessarily be regarded as a UAE complication or treatment failure, he says.
American Roentgen Ray Society
In a recent commentary written in conjunction with the study, by Fred Burbank, MD adds patients contemplating UAE should anticipate that fibroids bordering on or inside the uterine cavity may require cervical dilatation or hysteroscopic resection for removal. The addition of either of these gynecology procedures shouldn't necessarily be regarded as a UAE complication or treatment failure, he says.
American Roentgen Ray Society
Fibroids Current Events and Fibroids News RSSUC Davis researchers find decrease in hysterectomy complications
UC Davis researchers who studied hospital discharge records for nearly 650,000 California women over a 13-year period have found that complications from hysterectomies have significantly declined.
Treatment advances for fibroids, menopause
Women with fibroids and endometriosis facing the possibility of hysterectomy may now choose less invasive treatment options to preserve fertility, according to Yale professor Aydin Arici, M.D., who will direct a scientific session exploring these alternatives at the American College of Obstetricians and Gynecologists (ACOG) Annual Clinical Meeting May 3-7 in New Orleans, Louisiana.
Major surgery no longer needed for the removal of uterine fibroids
The treatment of uterine fibroids with 3T MR-guided focused ultrasound (MRgFUS) is safe, non-invasive and effective, according to a recent study conducted by researchers at Weill Cornell Medical College in New York, NY.
Minimally invasive fibroid treatment fares well in multicenter trial
A new multicenter trial found that uterine artery embolization (UAE) is a good alternative to hysterectomy in women with symptomatic fibroids. The findings of the Embolisation versus Hysterectomy (EMMY) Trial appear in the March issue of the journal Radiology.
Mayo Clinic study finds focused ultrasound treatment of uterine fibroids long term symptom relief
A noninvasive, outpatient treatment for noncancerous uterine tumors provides sustained relief from symptoms, according to a new Mayo Clinic led collaborative study.
Focused ultrasound relieves fibroid symptoms in women
A noninvasive ultrasound procedure effectively shrinks uterine fibroids and significantly relieves fibroid-related symptoms in women.
Enhanced MR-guided focused ultrasound guidelines demonstrate improved efficacy and durability
Data released today show that MR-guided focused ultrasound (MRgFUS) is a more effective option for a broader population of uterine fibroid sufferers.
MicroRNAs Can Be Tumor Suppressors
University of Virginia researchers have discovered that microRNAs, a form of genetic material, can function as tumor suppressors in laboratory studies.
MicroRNAs as tumor suppressors
In the May 1st issue of G&D, Drs. Yong Sun Lee and Anindya Dutta (UVA) reveal that microRNAs can function as tumor suppressors in vitro.
Chance of hysterectomy predicted by multi-year study
A woman's chance of undergoing a hysterectomy can now be accurately predicted, according to new UCSF study findings.
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