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Clear racial discrepancies exist among patients with CKD
May 20, 2008Black patients have a higher risk of dying in the early stages of chronic kidney disease (CKD) than whites, according to a study appearing in the July 2008 issue of the Journal of the American Society Nephrology (JASN). The findings may explain why blacks have better survival rates once they reach advanced stages of the disease-in essence, because only the healthiest blacks are surviving long enough to develop later stages of the disease. If white patients are given better care in managing their condition early on, even less healthy patients may live to develop advanced disease. But, their compromised health may put them at increased risk of death in the long term compared with blacks.
In addition, the study's results indicate that racial differences in the death rates of chronic kidney disease patients depend more on sociological factors than on biological ones. Poverty and lack of education and medical insurance in particular may contribute to the high death rates among black individuals.
Previous research has documented that, in general, mortality rates for black individuals are persistently higher than those for whites. However, among patients with late-stage chronic kidney disease, the trend is reversed and black individuals have a survival advantage over whites. Hispanic patients also seem to have a survival advantage over whites in these situations.
Puzzled by this paradox, Dr. Rajnish Mehrotra of the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and colleagues set out to find an explanation. They assessed data from a total of 14,611 patients in the Third National Health and Nutrition Examination Survey (NHANESIII), a population-based survey of community-dwelling individuals.
The investigators found that 2,892 of the individuals in the survey had chronic kidney disease, 1,127 of whom died during follow-up. Among those with early-stage disease who were younger than 65 years, blacks had a 78% higher risk of death compared with whites. This elevated risk was significantly related to socioeconomic status and access-to-care. There was also a nonsignificant trend for higher mortality among Hispanics compared with whites.
Dr. Mehrotra and his team conclude that their findings may explain the lower mortality rates observed among black individuals with advanced kidney disease. Blacks may not be receiving as high a quality of care as whites during the early stages of their disease, so that only healthier blacks are surviving and developing later stages of chronic kidney disease.
"These data suggest that factors such as education, poverty, and lower probability of medical insurance may be more important in mediating the high risk for death among younger black individuals than are biologic differences," the authors write. "This, in turn, may help in prioritizing interventions aimed at reducing the disparities among younger black individuals with chronic kidney disease."
American Society of Nephrology
Puzzled by this paradox, Dr. Rajnish Mehrotra of the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and colleagues set out to find an explanation. They assessed data from a total of 14,611 patients in the Third National Health and Nutrition Examination Survey (NHANESIII), a population-based survey of community-dwelling individuals.
The investigators found that 2,892 of the individuals in the survey had chronic kidney disease, 1,127 of whom died during follow-up. Among those with early-stage disease who were younger than 65 years, blacks had a 78% higher risk of death compared with whites. This elevated risk was significantly related to socioeconomic status and access-to-care. There was also a nonsignificant trend for higher mortality among Hispanics compared with whites.
Dr. Mehrotra and his team conclude that their findings may explain the lower mortality rates observed among black individuals with advanced kidney disease. Blacks may not be receiving as high a quality of care as whites during the early stages of their disease, so that only healthier blacks are surviving and developing later stages of chronic kidney disease.
"These data suggest that factors such as education, poverty, and lower probability of medical insurance may be more important in mediating the high risk for death among younger black individuals than are biologic differences," the authors write. "This, in turn, may help in prioritizing interventions aimed at reducing the disparities among younger black individuals with chronic kidney disease."
American Society of Nephrology
Chronic Kidney Disease Current Events and Chronic Kidney Disease News RSSHigh Blood Pressure Easy to Miss in Children with Kidney Disease
Spot blood pressure readings in children with chronic kidney disease often fail to detect hypertension - even during doctor's office visits - increasing a child's risk for serious heart problems, according to research from Johns Hopkins Children's Center and other institutions. A report of the findings appears online in the Journal of American Society of Nephrology.
Women with chronic kidney disease more likely than men to go undiagnosed
Woman are at particular risk of their primary care physicians delaying diagnosis of chronic kidney disease (CKD), according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, California.
For dialysis patients, skinny is dangerous
Dialysis patients with low body fat are at increased risk of death-even compared to patients at the highest level of body fat percentage, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego.
Link between depression, early stages of chronic kidney disease found by researchers
One in five patients with chronic kidney disease is depressed, even before beginning long-term dialysis therapy or developing end-stage renal disease, UT Southwestern Medical Center researchers have found.
Protein excreted in urine may be help in diagnosing kidney disease caused by HIV
New data collected at Columbia University Medical Center and by the Mount Sinai School of Medicine are helping researchers understand the extent to which a certain protein - NGAL - can play a significant role in marking chronic kidney disease resulting from HIV while at the same time distinguishing nephropathy from more common causes such as diabetes and hypertension.
A first choice of renal function tests in hepatectomy patients
Although creatinine clearance (Ccr) has been measured clinically by a simple method as a preoperative renal function test, Ccr is not strictly equal to glomerular filtration rate (GFR).
Study finds novel genetic risk factors for kidney disease
A team of researchers from the United States, the Netherlands and Iceland has identified three genes containing common mutations that are associated with altered kidney disease risk.
Robotic approach to urothelial cancer of the kidney proves to be beneficial for patients
Robotic trained surgeons at Fox Chase Cancer Center in Philadelphia presented a new and novel approach to surgically treat urothelial cancer (in the lining of the bladder or kidney) today at the American Urological Association's Annual Meeting.
Test predicts who will develop end-stage renal disease
Measuring kidney function by assessing two different factors-glomerular filtration rate (GFR) and urinary albumin levels-helps determine which patients with chronic kidney disease (CKD) will develop end-stage renal disease (ESRD).
Proteins from garden pea may help fight high blood pressure, kidney disease
Researchers in Canada are reporting that proteins found in a common garden pea show promise as a natural food additive or new dietary supplement for fighting high blood pressure and chronic kidney disease (CKD). Those potentially life-threatening conditions affect millions of people worldwide.
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Clinical Management of Chronic Kidney Disease by William M. Mcclellan (Author), Anton C. Schoolwerth (Author), Todd Gehr (Author) Adverse outcomes of CKD, including end-stage renal disease, cardiovascular disease (CVD), and premature death, can be prevented or delayed by medical interventions. This handbook presents diagnostic tools to identify the CKD patient in the outpatient practice setting, including risk stratification. Comprehensive management strategies to reduce the risk of CKD and maximize the health of the CKD patient are presented, including proper management of hypertension, CVD risk factors, proteinuria, anemia, and renal bone disease. |
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Living with Chronic Kidney Disease (Home Use) Part of the award winning public television series Healthy Body/Healthy Mind. More than twenty million Americans, one in nine adults, have chronic kidney disease, making it the ninth leading cause of death in the United States. What's more alarming, is that about twenty million others are at increased risk for the condition, largely due to climbing rates of diabetes and high blood pressure. Unfortunately, most Americans don't know anything about this silent epidemic until it's too late and won't discover their own kidney problems until they experience life-threatening symptoms. This product is manufactured on demand using DVD-R recordable media. Amazon.com's standard return policy will apply. |
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Living with Chronic Kidney Disease Directed By: (c) Information Television Network |
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Epakitin for Dogs and Cats, 150 gm by Vetoquinol Epakitin, a new nutritional supplement from Vétoquinol USA, Inc., safely and effectively supports kidney function and helps slow down the progression of chronic kidney disease. Easy to use in cats and dogs Helps pets feel better and live longer Great-tasting, easy-to-administer powder Can be used alone, mixed with regular food or in combination with a prescription renal diet Chronic Kidney Disease is one of the leading causes of death in dogs and cats. In North America, it is estimated that 8% of cats aged 10 years or more suffer from CKD. CKD affects approximately 2.4% of dogs aged 10 years or older. The diagnosis of Chronic Kidney Disease is generally based on low urine density and the increase of creatininemia, uremia and hyperphosphatemia, as well as clinical symptoms. By the... |
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Kidney Well II (2 Bottles), Alisma (2 Bottles) - Concentrated Herbal Blend and Extract - Dietary Supplement by Get Well Natural Kidney Well II is natural herbal based supplement with 7 key ingredients chosen for their anti-oxidants, cellular cleansing and cellular energy enhancing properties. The developing doctors' goal was to use these herbs in specific formulas to create optimal body balance for maintaining properly functioning kidneys.* In their experience, these herbs were highly beneficial to promote balancing effects for people at risk for imbalances associated with kidney disease, high creatinine levels, protein spillage, chronic glomerulonephritis, focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, proteinuria, IgA nephropathy, chronic renal failure, polycystic kidney disease, kidney failure, low kidney function as well as drug induced kidney pathologies.* Alisma contains a single... |
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Coping with Kidney Disease: A 12-Step Treatment Program to Help You Avoid Dialysis by Mackenzie Walser (Author), Betsy Thorpe (Author) A revolutionary program that can indefinitely postpone the need for dialysis If you’ve been diagnosed with kidney failure, this book could save your life. If you suffer from diabetes, hypertension, obesity, or any of a host of conditions that put you at risk for kidney disease, you owe it to yourself to read what is in this book. If you are among the 60,000 North Americans who go on dialysis each year, the information in this book could substantially improve your quality of life. In Coping with Kidney Disease, a leading expert tells you, in plain English, what you need to know to: Understand kidney failure Recognize early warning signs of kidney failure Get a proper diagnosis Talk with your doctors about it Confidently evaluate treatment options Take charge... |
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Epakitin 300 gm by Vetoquinol Epakitin, a new nutritional supplement from Vétoquinol USA, Inc., safely and effectively supports kidney function and helps slow down the progression of chronic kidney disease. Easy to use in cats and dogs Helps pets feel better and live longer Great-tasting, easy-to-administer powder Can be used alone, mixed with regular food or in combination with a prescription renal diet Chronic Kidney Disease is one of the leading causes of death in dogs and cats. In North America, it is estimated that 8% of cats aged 10 years or more suffer from CKD. CKD affects approximately 2.4% of dogs aged 10 years or older. The diagnosis of Chronic Kidney Disease is generally based on low urine density and the increase of creatininemia, uremia and hyperphosphatemia, as well as clinical symptoms. By the... |
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Chronic Kidney Disease: Are You at Risk? (Home Use) Part of the award winning public television series Healthy Body/Healthy Mind. Chronic kidney disease may not get as much attention as diabetes, but it's nearly as common - affecting one out of every nine adults. In today's program, we discover who is most at risk and trace the progression of the disease from onset to life-threatening kidney failure. We also hear first hand what life is like for patients who depend on dialysis. This product is manufactured on demand using DVD-R recordable media. Amazon.com's standard return policy will apply. |
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Managing Chronic Kidney Disease (A Desk Reference for Improving Patient Outcomes) by National Kidney Foundation (Author) | |
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Parsley Root - For chronic liver and gallbladder diseases, water retention, kidney congestion, 2 oz., (Health Herb) by HerbalLoveShop Parsley is a diuretic, blood purifier, carminative, and hepatic. PARSLEY ROOT (Petroselinum sativum) Useful for chronic liver and gallbladder diseases. The roots act most readily on the kidneys in comparison to other parts of the plant. Combine Parsley Root with Plantain and Marshmallow Root for kidney and bladder infections. It is strengthening for weak and sensitive people simply by adding a couple slices fo the root to a soup. Other indications: difficult urination, dropsy, jaundice, all stones, liver and spleen obstructions, asthma, water retention, coughs, kidney congestion, tumors, female problems, and after-pains of birth. CAUTION: Do not use if inflammation of the kidneys is present. For chronic liver and gallbladder diseases, water retention, kidney congestion. |
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