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MR imaging accurately determines prostate cancer treatment failure
May 20, 2008Dynamic contrast-enhanced MRI (DCE-MRI) plus diffusion weighted imaging (DWI) can accurately diagnose residual or recurrent prostate cancer in patients treated with high-intensity focused ultrasonic ablation, a new study shows.
The study included 27 patients who had increased levels of prostate specific antigen after being treated with high-intensity focused ultrasonic (HIFU) ablation; 18 of these patients had local tumor progression seen at biopsy. DCE-MRI and DWI had about a 72% accuracy rate in determining which patients needed additional treatment because they had residual or recurrent cancer, said Chan Kyo Kim, MD, lead author of the study. The study found that DWI had fewer false positives than DCE-MRI, but DCE-MRI had fewer false negatives.
"After HIFU ablation, the normal anatomy of the prostate gland is completely lost or deformed making it difficult to distinguish benign tissue from cancer," said Dr. Kim. The two imaging studies together, which can be done in about seven minutes, can overcome that challenge, he said.
HIFU is becoming more common as a prostate cancer treatment option, particularly for those persons who can't or don't want to undergo a radical prostatectomy, said Dr. Kim.
American Roentgen Ray Society
HIFU is becoming more common as a prostate cancer treatment option, particularly for those persons who can't or don't want to undergo a radical prostatectomy, said Dr. Kim.
American Roentgen Ray Society
Prostate Cancer Current Events and Prostate Cancer News RSSNew Catheter-less Technique May Ease the Pain and Discomfort of Prostate Cancer Recovery
To ease the pain of recovery following prostate cancer surgery, physician-scientists have developed an innovative and patient-friendly approach that eliminates the use of a penile urinary catheter.
Racial disparities decline for cancer in Missouri
Cancer death rates in the United States are highest among African Americans, but a new report shows that in Missouri the disparity in cancer incidence and death between African Americans and whites is declining.
OHSU Cancer Institute researchers study breathing during radiation
Oregon Health & Science University researchers have determined exactly how much breathing affects prostate movement during radiation treatment.
Hormone therapy before radiation seed implants for prostate cancer
Men over 70 years of age with early-stage prostate cancer have 20 percent higher mortality if they are treated first with hormone therapy before being treated with radiation seed implants (brachytherapy), compared to men who are treated with brachytherapy alone.
Newly found gene variants account for kidney diseases among African-Americans
For the first time, researchers have identified variations in a single gene that are strongly associated with kidney diseases disproportionately affecting African-Americans. This work was conducted by researchers at the National Institutes of Health (NIH) and by NIH-funded investigators at the Johns Hopkins University.
Common painkillers lower levels of prostate cancer biomarker
Common painkillers like aspirin and ibuprofen appear to lower a man's PSA level, the blood biomarker widely used by physicians to help gauge whether a man is at risk of prostate cancer.
Anti-inflammatory drugs may mask prostate cancer marker
Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, may reduce serum levels of the prostate biomarker, PSA (prostate specific antigen), and hence may alter the detection of prostate cancer in individuals who take these medications.
Too much calcium in blood may increase risk of fatal prostate cancer
Men who have too much calcium in their bloodstreams may have an increased risk of fatal prostate cancer, according to a new analysis from Wake Forest University School of Medicine and the University of Wisconsin.
Height linked to risk of prostate cancer development and progression
A man's height is a modest marker for risk of prostate cancer development, but is more strongly linked to progression of the cancer, say British researchers who conducted their own study on the connection and also reviewed 58 published studies.
Health risk behaviors associated with lower prostate specific antigen awareness
According to a study conducted at Columbia University Mailman School of Public Health, health risk behaviors such as smoking and obesity are associated with lower awareness of the Prostate Specific Antigen (PSA), which could lead to a lower likelihood of undergoing actual prostate cancer screening.
More Prostate Cancer Current Events and Prostate Cancer News Articles
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