|
Risk threshold of daily alcohol intake and drinking duration in liver injury?
May 21, 2008Alcoholic threshold effect rather than a dose-response effect on mortality from alcohol-related liver injury. Alcohol intake, rather than the type of alcoholic beverage, was more significant to liver injury.
This study, performed by a team led by by Professor You-Ming Li from Zhejiang University, is described in a research article to be published on April 7, 2008 in the World Journal of Gastroenterology.
The study shows that the risk threshold of daily alcohol intake and the duration of drinking inducing alcohol-related liver injury is 20 g and 5 years in the island population of China. Liver injury induced by obesity should be concerned.
In the view of the authors, to date no clear explanation has existed to evaluate alcohol-related liver injury in China's island population.
The island population east of China is a specific cluster population. Their alcohol consumption is very high compared to that of the mainland population. However, there is a lack of population-based alcoholic liver disease (ALD) studies on China's islands.
The authors conducted a population-based case-control study to investigate the association of alcohol dose, duration of drinking and obesity with liver injury in the island population east of China.
The results will be useful in further analyzing the differences between the island population and the inland population, in terms of drinking habits, diet habits, life and work pressure and genotype. The island population should be further studied in follow-up research.
World Journal of Gastroenterology
In the view of the authors, to date no clear explanation has existed to evaluate alcohol-related liver injury in China's island population.
The island population east of China is a specific cluster population. Their alcohol consumption is very high compared to that of the mainland population. However, there is a lack of population-based alcoholic liver disease (ALD) studies on China's islands.
The authors conducted a population-based case-control study to investigate the association of alcohol dose, duration of drinking and obesity with liver injury in the island population east of China.
The results will be useful in further analyzing the differences between the island population and the inland population, in terms of drinking habits, diet habits, life and work pressure and genotype. The island population should be further studied in follow-up research.
World Journal of Gastroenterology
Liver Injury News and Current Liver Injury Events RSSGene-expression profiling of the effects of liver toxins
Gene-expression data from liver tissue or whole blood can be used to classify histopathologic differences in the effects of hepatotoxins. It is hoped that these findings, published in BioMed Central's open access journal, Genome Biology, will lead to a more precise way of defining the potential hepatotoxicity of new compounds.
An emerging candidate for protecting patients from liver injury after abdomen surgery
Many patients worldwide are going to receive major abdomen surgery or intestine transplantation every year and expect to be afflicted with liver injury afterwards.
Researchers show that fibrosis can be stopped, cured and reversed
University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.
Unique pattern of gene expression can indicate acetaminophen overdose
In a new study, researchers found they could detect toxic levels of acetaminophen in laboratory animals by analyzing gene expression in the blood.
Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage.
UCSD researchers identify critical receptor in liver regeneration
In studies in mouse models, researchers at the University of California, San Diego (UCSD) School of Medicine have found that a cellular receptor involved in triggering cell death is also a necessary component of tissue repair and regeneration immediately following liver injury.
Non-steroidal anti-inflammatory drug increases liver damage in mice carrying mutant human gene
Alpha-1-antitrypsin deficiency isn't a term that rolls right off the tongue. But people diagnosed with this genetic disorder learn its potential effects well.
American Thoracic Society publishes new statement on hepatotoxicity of antituberculosis therapy
The American Thoracic Society (ATS) has published a new statement on the pathogenesis, prevention and treatment of liver damage caused by anti-tuberculosis (TB) medications.
Researchers estimate significant fatty liver disease in children
Until now little was known about the prevalence of non-alcoholic fatty liver disease (NAFLD) in children.
Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells —possibly dormant from the earliest developmental stage of a human being — which have the potential to mature into different cells types and help repair a failing liver.
More Liver Injury News Articles
| © 2008 BrightSurf.com |