 |
|
How to diagnose and treat Gardner syndrome with gastric polyposis
May 21, 2008Gardner syndrome (GS) is a rare, autosomal, dominant inherited disorder with a high degree of penetrance characterized by the triad: intestinal polyposis and various bone and soft-tissue tumors. It is regarded as a clinical subgroup of familial adenomatous polyposis (FAP).
This case, reported by a team led by Dr. Shi-Lin Wang, is described in a research article to be published on April 7, 2008 in the World Journal of Gastroenterology.
A 23-year-old female presented with nausea, vomiting and mucous diarrhea with occasional blood in the stool, especially after dining. Colonoscopy delineated numerous polyps carpeting the entire colon and rectum, mostly in the sigmoid colon and rectum, which is consistent with the diagnosis of FAP. Gastroscopy delineated numerous polyps carpeting mainly the fundus ventriculi but also the corpus ventriculi. The patient was treated with restorative proctocolectomy with ileal pouch anal anastomosis (RPC/IPAA), ileostomy and ileostomy closure operations, and twice with snare polypectomy over an eight month period. The patient gradually recovered from innutrition and anemia.
It was reported that 25% of patients with GS had no family history; moreover the miniaturization of family also made the hereditary behavior unobvious. When faced with a patient with colorectal polypi in the clinic, doctors should pay attention to examining the patient's stomach, thyroid, tooth, skull and eye ground. The examination of APC and MYH mutation are helpful in diagnosing patients with GS and FAP.
World Journal of Gastroenterology
It was reported that 25% of patients with GS had no family history; moreover the miniaturization of family also made the hereditary behavior unobvious. When faced with a patient with colorectal polypi in the clinic, doctors should pay attention to examining the patient's stomach, thyroid, tooth, skull and eye ground. The examination of APC and MYH mutation are helpful in diagnosing patients with GS and FAP.
World Journal of Gastroenterology
Polyposis Current Events and Polyposis News RSSM. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers
Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers.
A surprise 'spark' for pre-cancerous colon polyps
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous tumors.
ASGE encourages patients to speak to their doctor about colorectal cancer screening options
Results of the National CT Colonography Trial, published in the September 18 issue of the New England Journal of Medicine, show improvements in the technology's ability to diagnose intermediate- to large-sized polyps in the colon, but this method of testing is not as effective in diagnosing small polyps
'1-hit' event provides new opportunity for colon cancer prevention, say Fox Chase researchers
More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer.
Colon cancer risk in US traced to common ancester
A married couple who sailed from England to America around 1630 may be the ancestors of hundreds of people alive today who are at risk for a hereditary form of colon cancer.
A new way to treat colon cancer?
Researchers at University of Utah's Huntsman Cancer Institute have discovered a new target for possible future colon cancer treatments - a molecule that is implicated in 85 percent of colon cancer cases.
Chemicals in curry and onions may help prevent colon cancer
A small but informative clinical trial by Johns Hopkins investigators shows that a pill combining chemicals found in turmeric, a spice used in curries, and onions reduces both the size and number of precancerous lesions in the human intestinal tract.
New test spares couples with familial cancer the trauma of termination
A new way of sparing couples the trauma of having to decide between having a baby with a high risk of developing a form of colorectal cancer later in life, or terminating the pregnancy.
Study: Exercise, diet may protect against colorectal cancer
Voluntary exercise and a restricted diet reduced the number and size of pre-cancerous polyps in the intestines of male mice and improved survival, according to a study by a University of Wisconsin-Madison research published May 13 in the journal Carcinogenesis.
Studies shed new light on why exercise can protect against skin and bowel cancers
Two studies have shown that exercise can protect against skin and bowel cancer, and they have identified new mechanisms that could be responsible for this effect.
More Polyposis Current Events and Polyposis News Articles
 |
Intestinal Polyps and Polyposis: From Genetics to Treatment and Follow-up by Gian Gaetano Delaini (Editor), Thomas Skricka (Editor), Gianluca Colucci (Editor), John Nicholls (Editor) Nowadays, we are dealing more frequently with the entity of large intestine polyps, as endoscopy and bowel cancer screening programmes are rapidly expanding. Often a single polyp is involved, but more complex situations are also encountered, including the well-defined pattern of polyposis. These situations can fall into a gray area, not only for diagnosis, but also for the correct treatment and follow-up. New developments in pathophysiology and treatment options are leading to new questions. This handbook aims to offer an integrated approach for all physicians (doctors) who deal with these issues, by presenting up-to-date discussion from genetics through treatment, to implications of genetic counseling. It will also help specialists to offer more 'evidence-based' treatments, by... |
 |
Familial Polyposis Awareness Ribbon Mouse Pad by MyHeritageWear.com The Familial Polyposis Ribbon proudly displayed on a mouse pad. There is no better way to achieve awareness for the meaning of the Familial Polyposis Ribbon than to display it on your mouse pad for everyone to see. The mouse pad measures at 9.25 x 7.75, it is machine washable, and the colors will not fade or run. Start gaining awareness today by presenting your Familial Polyposis Ribbon mouse pad at work or at home. It is certain to keep your mouse rolling in style all while gaining support and awareness! |
|
Treatment is key to preventing ca in FAP patients.(Genetic Testing Indicated)(familial adenomatous polyposis): An article from: Internal Medicine News by Robert Finn (Author) This digital document is an article from Internal Medicine News, published by International Medical News Group on March 15, 2004. The length of the article is 480 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Treatment is key to preventing ca in FAP patients.(Genetic Testing Indicated)(familial adenomatous polyposis) Author: Robert Finn Publication: Internal Medicine News (Magazine/Journal) Date: March 15, 2004 Publisher: International Medical News Group Volume: 37 Issue: 6 Page: 79(1) Distributed by Thomson... | |
|
Familial Polyposis: An entry from Gale's Gale Encyclopedia of Medicine, 3rd ed. by Ellen, MSN Weber (Author) This digital document is an article from Gale Encyclopedia of Medicine, 3rd ed., brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses. The length of the article is 1711 words. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. The third edition of this authoritative, comprehensive, in-depth medical guide features information on medical topics in language accessible to adult laypersons. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes;... | |
![MUTYH-associated polyposis-From defect in base excision repair to clinical genetic testing [An article from: DNA Repair]](http://ecx.images-amazon.com/images/I/51FZ3K9Y7XL._SL160_.jpg) |
MUTYH-associated polyposis-From defect in base excision repair to clinical genetic testing [An article from: DNA Repair] by J.P. Cheadle (Author), J.R. Sampson (Author) This digital document is a journal article from DNA Repair, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser. Description: Established predisposition genes account for only a small proportion of familial colorectal cancer. Recently, it has been shown that germline mutations in MUTYH predispose to MUTYH-associated polyposis (MAP), an autosomal recessive disorder characterised by multiple colorectal adenomas and carcinomas. MUTYH functions as a base excision repair DNA glycosylase that excises adenines misincorporated opposite 8-oxo-7,8-dihydro-2'-deoxyguanosine, one of the most stable products of oxidative DNA damage. It is the failure to... |
|
Treatment is key to cancer prevention in FAP patients; genetic testing indicated.(Clinical Rounds)(familial adenomatous polyposis): An article from: Family Practice News by Robert Finn (Author) This digital document is an article from Family Practice News, published by International Medical News Group on April 15, 2004. The length of the article is 1946 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Treatment is key to cancer prevention in FAP patients; genetic testing indicated.(Clinical Rounds)(familial adenomatous polyposis) Author: Robert Finn Publication: Family Practice News (Magazine/Journal) Date: April 15, 2004 Publisher: International Medical News Group Volume: 34 Issue: 8 Page: 23(1) Distributed by Thomson... | |
|
Polyps and Polyposis of the Colon by Leonardo and Luigi, Barbara Possati (Author) | |
|
Gale Encyclopedia of Medicine: Familial polyposis by Ellen S. Weber MSN (Author) The article is excerpted from Gale Encyclopedia of Medicine. Consult the second edition of this authoritative, comprehensive, in-depth medical guide for information on more than 1,700 medical topics in language accessible to adult laypersons. Presented in a single alphabetical sequence, articles range in length from one or two paragraphs for minor topics, to several pages or more for major topics. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. This second edition includes more than 200 new entries, 300 updated entries, approximately 650 color... | |
|
Familial Polyposis Coli by Professor H. J. R. Bussey (Author) | |
|
|
Familial Polyposis Awareness Ribbon Mouse Pad by MyHeritageWear.com The Familial Polyposis Ribbon proudly displayed on a mouse pad. There is no better way to achieve awareness for the meaning of the Familial Polyposis Ribbon than to display it on your mouse pad for everyone to see. The mouse pad measures at 9.25 x 7.75, it is machine washable, and the colors will not fade or run. Start gaining awareness today by presenting your Familial Polyposis Ribbon mouse pad at work or at home. It is certain to keep your mouse rolling in style all while gaining support and awareness! |
| © 2009 BrightSurf.com |