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How to increase the chances of remaining virus free Pakistani patients with HCV?
May 21, 2008Hepatitis C is a health care problem all over the world, with 130 million patients infected the world over. The treatment is expensive and has variable results according to the genotype of the infecting virus. The first land mark in treatment is the virus clearance at the end of the treatment called End Treatment Response (ETR), but many of the patients achieving the ETR have a relapse within the next six months. Thus, the goal of treatment is to have persistent virus clearance until six months after completing the treatment. This is called Sustained Virological Response (SVR). It is difficult to predict the SVR in patients receiving ongoing therapy.
A team of doctors, led by Dr. Bader Faiyaz Zuberi at Dow University of Health Sciences, Pakistan, conducted a study and their article will be published on April 14, 2008 in the World Journal of Gastroenterology. In this article they show that in patients with genotype-3 HCV who achieve virus clearance in the first four weeks of therapy, called Rapid Virological Response (RVR) with standard interferon, there is a high probability of achieving the SVR. They also show that patients with initial high levels of ALT were also more likely to attain RVR.
The study will help in selection and prediction of response in patients with Hepatitis C being treated with standard interferon. Pegylated interferon is very expensive and is not within the reach of most patients in developing countries.
World Journal of Gastroenterology
World Journal of Gastroenterology
Hepatitis Current Events and Hepatitis News RSSToward explaining why hepatitis B hits men harder than women
Scientists in China are reporting discovery of unusual liver proteins, found only in males, that may help explain the long-standing mystery of why the hepatitis B virus (HBV) sexually discriminates -- hitting men harder than women.
Largest-ever database for liver proteins may lead to treatments for hepatitis
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Mount Sinai finds those with more difficult to treat forms of HCV are half as likely to get treated
A new study by Mount Sinai researchers has for the first time found that patients with more difficult to treat forms of hepatitis C are half as likely to initiate treatment for the disease, when compared to patients with hepatitis C that is easier to treat.
Extending treatment after liver transplant may benefit patients with hepatitis C recurrence
Extending hepatitis C treatment for liver transplant patients beyond current practice results in high rates of clearance of the hepatitis C virus from the blood, as well as a low rate of relapse, according to a Henry Ford Hospital study.
Hepatitis B does not increase risk for pancreatic cancer
A Henry Ford Hospital study found that hepatitis B does not increase the risk for pancreatic cancer - and that only age is a contributing factor.
Governor recognizes stem cell research at Einstein
Albert Einstein College of Medicine of Yeshiva University hosted a roundtable discussion on stem cell research with New York Governor David A. Paterson today.
Liver cells grown from patients' skin cells
Scientists at The Medical College of Wisconsin in Milwaukee have successfully produced liver cells from patients' skin cells opening the possibility of treating a wide range of diseases that affect liver function.
Injury and hazards in home health care nursing are a growing concern
Patients continue to enter home healthcare ''sicker and quicker," often with complex health problems that may require extensive nursing care.
Medication effective for acute liver failure in early stages of disease
The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found.
New aging studies improving vaccine efficacy for the elderly
A new study from the Trudeau Institute in Saranac Lake, New York, demonstrates that immune system cells important for both pathogen resistance and vaccine efficacy live longer in older animals but because of this longevity acquire functional defects.
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