The secret behind silkworm's hardy stomachsMay 28, 2008Silkworms have a unique ability to eat toxic mulberry leaves without feeling ill, and researchers have come one step closer to understanding why: silkworms contain a special digestive enzyme that is not affected by mulberry's toxic chemicals. Mulberry leaves contain an extremely high amount of alkaloids that inhibit enzymes that break down sucrose (sugar), and thus are potentially quite toxic. However, one type of sucrase called beta-fructofuranosidase is not affected by these alkaloids. Until now, this enzyme has not been found in any animals, but Toru Shimada and colleagues believed this might explain the silkworm's unique diet. The researchers scanned the silkworm genome and discovered two fructofuranosidase genes, although only one was actually expressed in the worm. This gene (BmSuc1) was, as expected, concentrated in the worm's gut, although surprisingly was also prevalent in the silk gland. When they isolated the enzyme from silkworms, the researchers found it could effectively digest sucrose. Shimada and colleagues note that further work is needed to determine if this special enzyme is the sole reason for silkworm's resistance to mulberry toxins. It's possible that fructofuranosidases may turn up in other insects that cannot eat mulberry leaves, indicating additional factors are at work. American Society for Biochemistry and Molecular Biology |
|||||||||||||||||||||
| Related Silkworm Current Events and Silkworm News Articles How the 100th protein structure solved at Diamond impacts our understanding of how insects smell New research announced today, Wednesday 30th September, by a team of leading scientists working with the UK's national Synchrotron, Diamond Light Source, could have a significant impact on the development and refinement of new eco-friendly pest control methods for worldwide agriculture. Scientists discover how to send insects off the scent of crops Biotechnology and Biological Sciences Research Council (BBSRC)-funded research, published this week in Chemical Communication, describes how scientists have discovered molecules that could confuse insects' ability to detect plants by interfering with their sense of smell. This could reduce damage to crops by insect pests and contribute to food security. Human genomics in China Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai. To commemorate this important event, which marks the beginning of the Genomics Era in China, we specially organize a series of mini-reviews for this special issue. Can fish factories make cheap drugs? Written by Amitabh Avasthi A HUMAN blood-clotting factor used to treat some people with haemophilia and accident victims suffering serious bleeding has been produced using genetically modified fish. Nature press release for 15 August issue [1] LIFELINES: APES LACK ELEMENTS OF LANGUAGE GENE (DOI: 10.1038/nature01025) (http://dx.doi.org/10.1038/nature01025) ***This paper will be published electronically on Nature`s website on 14 August at 1900 London time / 1400 US Eastern time (which is also when the embargo lifts) as part of our AOP (ahead of print) programme. Although we have included it on this release to avoid multiple mailings it will not appear in print on 15 August, but at a later date.*** Language, a uniquely human trait, relies on capabilities such as fine control of the larynx and mouth. In a paper published online in Nature this week, researchers have begun to work out why chimpanzees and other great apes lack thes More Silkworm Current Events and Silkworm News Articles |
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||