OHSU Cancer Institute researchers find many stomach cancer patients are not gertting best therapyMay 30, 2008New data shows majority of patients with stomach cancer are not benefiting from a major study showing chemotherapy and radiation prolong life after surgery PORTLAND, Ore. - New findings from Oregon Health & Science University Cancer Institute show significant numbers of patients nationwide who are not getting the recommended therapy after surgery to remove stomach cancer. "We were surprised to learn that there are still many patients who are not receiving the gold standard of chemotherapy and radiation after surgery - despite compelling clinical data available since 2001. However, it is encouraging to see there has been a significant increase in the use of chemo-radiotherapy since it became the standard of care," said Kristian Enestvedt, M.D., principal investigator, Department of Surgery, OHSU School of Medicine, OHSU Cancer Institute. One million people die of stomach cancer worldwide each year. This study by Enestvedt and his colleagues will be presented Sunday, June 1, at 8 a.m. during the annual American Association of Clinical Oncology conference in Chicago. In 2001 a seminal study showed that using chemotherapy and radiation, also called chemo radiotherapy, after gastric cancer surgery increased survival. Other studies have also recommended that at least 15 lymph nodes should be removed with gastric resection surgery. But little data has existed until now about whether this recommended practice was being followed. For this study, 313 patient cases were gleaned from a state-wide cancer registry. The chemo/radiation therapy was used only 14.2 percent of the time before 2001 versus, and 33.3 percent after that date. "That still leaves almost 67 percent of cases left in which patients did not get the appropriate - and potentially life-extending - therapy. We found that there was a five-month survival advantage for patients who received chemo radiotherapy," Enestvedt said. Also, researchers found that only 35 percent of patients had at least 15 nodes removed to check for cancer. The number of lymph nodes removed, however, did not affect survival. "What patients should know is that they should routinely ask their physicians if their treatment plan includes the latest clinical trial data that pertains to their particular situation," said Charles Thomas, M.D., co-author, chairman and professor of radiation medicine, OHSU School of Medicine, OHSU Cancer Institute member. Oregon Health & Science University |
|||||||||||||||||||||
| Related Stomach Cancer Current Events and Stomach Cancer News Articles Uncovering the secrets of ulcer-causing bacteria A team of researchers from Boston University, Harvard Medical School and Massachusetts Institute of Technology recently made a discovery that changes a long held paradigm about how bacteria move through soft gels. What are factors associated with use of gastric cancer screening services in Korea? The mortality of gastric cancer is decreasing despite the increasing incidence in Korea. This can be explained by surgical technique development and early detection by endoscopic screening or upper gastrointestinal study. Heavy drinkers face significantly increased cancer risk Heavy drinkers of beer and spirits face a much higher risk of developing cancer than the population at large, says a group of Montreal epidemiologists and cancer researchers. Simple measures may prevent transmission of stomach ulcer bacteria The stomach ulcer bacterium Helicobacter pylori is not transmitted through drinking water as previously thought, but rather through vomit and possibly faeces. Columbia team finds that gastrin plays significant role in helicobacter-induced stomach cancer A group led by Columbia University Medical Center's Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach. Tummy troubles -- gastrin key in bacterial-induced stomach cancer Current research suggests that levels of gastrin play a key role in the development of Helicobacter-induced stomach cancer. Glutamine supplements show promise in treating stomach ulcers Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Novel therapy may prove effective in treatment of 30 percent of cancers A ground-breaking Canada-wide clinical trial led by Dr. Katherine Borden, at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, has shown that a common anti-viral drug, ribavirin, can be beneficial in the treatment of cancer patients. New minimally invasive surgery option for patients with stomach cancer A novel, minimally invasive surgical approach to treat stomach cancer has been shown to have advantages that may make it a preferable treatment for some patients. Broccoli sprouts may prevent stomach cancer by defeating Helicobacter pylori Three-day-old broccoli sprouts, a widely available human food, suppressed Helicobacter pylori (H. pylori) infections, according to a report in Cancer Prevention Research, a journal of the American Association for Cancer Research. H. pylori infections are one of the most common bacterial infections worldwide and are a major cause of stomach cancer. More Stomach Cancer Current Events and Stomach Cancer News Articles |
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||