Science Current Events | Science News | Brightsurf.com
 
Email a Friend Send to a friend
Printer Friendly Print CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease
Slashdot It! Slashdot CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease
Submit to Reddit Submit CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease to Reddit
Reading: CV risk management should be mandatory in RA and other types of inflammatory rheumatic diseaseTwitter This Reading: CV risk management should be mandatory in RA and other types of inflammatory rheumatic diseaseTwitter CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease
Add to Facebook Add CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease to Facebook

CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease

June 16, 2008

Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients should undergo compulsory cardiovascular (CV) risk management and existing CV risk calculators should be adapted to the increased CV risk in inflammatory rheumatic disease patients, the EULAR Task Force on 'Cardiovascular Risk Management in RA' recommended today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

RA, AS and PsA are associated with an increased CV risk and, in RA, this risk is at least double the norm and potentially similar to that of type 2 diabetes, a clinically-established cardiovascular risk factor. The EULAR Task Force set out to review existing evidence and expert opinion-based recommendations on CV management in inflammatory rheumatic disease, in order to devise specific EULAR recommendations for future clinical practice.




The EULAR Task Force's multidisciplinary steering committee comprised 21 members, including rheumatologists, cardiologists, internists and epidemiologists, from across nine European countries (France, Germany, Greece, Hungary, Norway, Portugal, Spain, The Netherlands, United Kingdom). Their recommendations were as follows:

1. RA, AS and PsA should become clinically accepted as new CV risk factors.

2. Existing CV-risk calculators, such as the Framingham and Systematic Coronary Risk Evaluation (SCORE), should be adapted, by a multiplier, to reflect the increased CV risk in inflammatory rheumatic disease patients.

3. Annual cardiovascular risk screening is recommended for all RA patients and should be considered for AS and PsA patients.

4. Lifestyle recommendations (on areas including diet, exercise, smoking cessation and stress management) should be given to all inflammatory rheumatic disease patients.

5. Treatment with statins and/or antihypertensives should be considered, and the CV management targets should be set according to local guidelines. If there are no local guidelines, treatment should be considered when the 10 year CV mortality risk with the (newly adapted) Framingham/SCORE function is above a certain value.

6. Aggressive inflammation suppression is recommended to further lower the CV risk in patients with inflammatory rheumatic disease.

Dr Michael Nurmohamed, lead investigator and convenor of this EULAR Task Force said, "Although traditional cardiovascular risk factors occur more frequently in patients with inflammatory rheumatic disease than in the general population, they only partially explain these patients' increased cardiovascular risk. There is mounting evidence that inflammation may be the missing link. Therefore, disease modifying antirheumatic drugs (DMARD) and biologics may lower the cardiovascular risk in inflammatory rheumatic disease patients, whilst statins and hypertensives, such as ACE inhibitors and angiotensin blockers, may even yield greater benefits than in the general population due to their anti-inflammatory properties."

Professor Ferdinand Breedveld, President of EULAR said, "These recommendations have been developed in accordance with the EULAR Standardised Operating Procedures and in line with the EULAR objectives to improve the understanding of musculoskeletal disorders and contribute to the improvement of outcome of patients with rheumatic disorders. The Task Force is to be commended on its excellent recommendations which will directly contribute to improved clinical practice and better understanding of the management of CV factors in rheumatology."

CV risk factor stratification and management is currently conducted on the basis of 10 years absolute risk for a (fatal) CV-event, as derived from a risk formula based on a number of CV-risk factors. The two major standard CV risk calculators are Framingham, a tool based on US population statistics and SCORE, tailored to European populations.

European League Against Rheumatism





Science News and Science Current Events Tag Cloud
This tag cloud is a visual representation of term frequencies of random science news topics with common terms grouped together and emphasized by their display size.
General Relativity   Infectious Disease   Malaria parasite   Sturgeon   Autoimmune   Marine Species   Lymphedema   Cloning   Tinnitus   Insecticide   Morphine   Type 1 Diabetes   Climate Warming   Circumcision   Pluto   Blood Flow   Chronic Obstructive Pulmonary Disease   Methamphetamine   Ecosystem   Salmonella   Helicobacter pylori   Sea Ice   Ethanol   Sexual Abuse   Ferroelectric  
Related Rheumatic Disease Current Events and Rheumatic Disease News Articles Rheumatic Disease Current Events and Rheumatic Disease News RSS Rheumatic Disease Current Events and Rheumatic Disease News RSS
Better access to info and dialogue with HCPs on sexual issues for rheumatology patients
Patients with rheumatic diseases want more information and better communication with healthcare professionals on the sexual issues related to their conditions.

Over half of people with rheumatoid arthritis have periodontitis
Over half (56%) of people with rheumatoid arthritis (RA) also have periodontitis (a chronic inflammatory disease of the gum and surrounding ligaments and bones that hold the teeth in place), displaying fewer teeth than healthy matched controls, high prevalence of oral sites presenting dental plaque and advanced attachment loss (the extent of periodontal support that has been destroyed around a tooth) (chi square p<0.05).

Subclinical markers predict relapse in juvenile idiopathic arthritis post methotrexate withdrawal
Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status.

Stress tests to confirm need for cardiac stent not occurring in most patients, new study finds
UCSF researchers investigating the appropriate use of procedures to open narrowed coronary arteries -- such as angioplasty and stenting -- found that less than half of Medicare patients had documented noninvasive stress testing prior to elective percutaneous coronary intervention, or PCI, the clinical name for such procedures.

Hand bone mineral density is an effective predictor of mortality in rheumatoid arthritis
Low bone mineral density in the hand is a valid predictor of overall mortality in patients with rheumatoid arthritis (RA) and indicates long-term prognosis, according to a new study presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France. Digital X-ray radiogrammetry (DXR) demonstrated bone mineral density to be as effective predicting mortality as well-established means of assessment such as radiographic damage and functional disability.

The genes involved in rheumatoid arthritis identified
The human genome has now been thoroughly screened in the hunt for the genetic causes of rheumatoid arthritis. The results, which both confirms previous hypotheses and turn the spotlight on entirely new genes, are presented in two articles in the prestigious New England Journal of Medicine.

Childhood arthritis raises risk of broken bones
Childhood arthritis increases the risk of fractures, particularly during adolescence, according to a large study of British patient records.

Study Demonstrates Safety of Oral Contraceptives in Women with Lupus
In a major study, women with either inactive or stable systemic lupus erythematosus (lupus) - a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs - were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

Rheumatic disease increases risks in pregnancy, Stanford study finds
The first nationwide study of pregnancy outcomes in women with rheumatic disease confirms that they experience greater pregnancy risks and longer hospital stays than the average pregnant woman.

Aetiology of congenital heart disease explained
Researchers at Karolinska Institutet have identified the mechanisms behind the serious, congenital heart condition that can sometimes develop in children of women with a rheumatic disease.
More Rheumatic Disease Current Events and Rheumatic Disease News Articles
Primer on the Rheumatic Diseases (Primer on Rheumatic Diseases (Klippel))

Primer on the Rheumatic Diseases (Primer on Rheumatic Diseases (Klippel))
by John H. Klippel (Editor), John H. Stone (Editor), L eslie J. Crofford (Editor), Patience H. White (Editor)

One of the most prestigious, comprehensive texts on arthritis and related diseases, including osteoarthritis, rheumatoid arthritis, osteoporosis, lupus and more than one hundred others.



A Parent's Guide to Rheumatic Disease in Children

A Parent's Guide to Rheumatic Disease in Children
by Oxford University Press, USA

For a child with arthritis or a related condition, lack of knowledge on the part of the parents is one of the biggest obstacles to recovery. Parents do not always know how to interpret the complaints voiced by their children and this is compounded by the inexperience of physicians, who rarely treat children with these ailments.
In this marvelously down-to-earth guide, Dr. Thomas Lehman--the head of one of the leading pediatric rheumatology programs in the world--offers a gold mine of expert advice that is invaluable both for parents whose children have rheumatic disorders and for parents of children with complaints, discomfort, or disability who are not getting the answers they need from their physician. Using simple analogies and illustrative anecdotes to illuminate...

Rheumatic Diseases Chart

Rheumatic Diseases Chart
by American 3B Scientific

Rheumatic Diseases Chart Rheumatic Diseases ModelThis thickly laminated anatomical chart is printed on premium glossy (200 g) UV resistant paper and comes with 2 sided lamination (125 micron, 5.0 Mil) and metal eyelets to make the chart easy to display. It comes in a convenient poster size 50 x 67 cm (20x26’’) and can be written on and wiped off with non permenant markers. The 125 micron lamination ensures the chart does not curl up at the edges and the UV treament ensures the chart does not get a faded yellow color over time.Measurements:50 x 67 cm Weight: 0,15 kg Product photo may not exactly match the product offered for sale. Please refer to the product description.

Stethoscope Sounds: Heart Murmurs and Lung Sounds - a Woman with Rheumatic Heart Disease

Stethoscope Sounds: Heart Murmurs and Lung Sounds - a Woman with Rheumatic Heart Disease
by Folkways Records



  Kelley's Textbook of Rheumatology Online, Webstart DVD-ROM
Starring: Edward Harris, Ralph C. Budd, Gary S. Firestein, Mark C. Genovese, John S. Sergent



Kelley's Textbook of Rheumatology CD-ROM

Kelley's Textbook of Rheumatology CD-ROM
by Shaun Ruddy (Editor), Edward D. Harris (Editor), Clement B. Sledge (Editor), Ralph C. Budd (Editor), John S. Sergent (Editor)

Companion CD to Ruddy Textbook of Rheumatology 6th edition. Includes the entire 2 volume text/tables/illustrations and references plus additional color figures, and two 35 minute video loops. All of this on a single, easy-to-use CD!

A Parent's Guide to Rheumatic Disease in Children

A Parent's Guide to Rheumatic Disease in Children
by Thomas J.A. Lehman M.D. (Author)

For a child with arthritis or a related condition, lack of knowledge on the part of the parents is one of the biggest obstacles to recovery. Parents do not always know how to interpret the complaints voiced by their children and this is compounded by the inexperience of physicians, who rarely treat children with these ailments.
In this marvelously down-to-earth guide, Dr. Thomas Lehman--the head of one of the leading pediatric rheumatology programs in the world--offers a gold mine of expert advice that is invaluable both for parents whose children have rheumatic disorders and for parents of children with complaints, discomfort, or disability who are not getting the answers they need from their physician. Using simple analogies and illustrative anecdotes to illuminate...

PetAlive Muscle and Joint Support  for Pet Arthritis, Rheumatic Conditions and Hip Dysplasia (60 Caps)

PetAlive Muscle and Joint Support for Pet Arthritis, Rheumatic Conditions and Hip Dysplasia (60 Caps)
by PetAlive

PetAlive Muscle and Joint Support capsules are specially formulated for pets and contain a unique formula combining herbal medicines, biochemic tissue salts and nutritional substances all well known for their therapeutic and protective effect on the skeletal system, including muscles, joints, cartilage and tendons. Muscle and Joint Support is an excellent choice for pets suffering from arthritis, rheumatism and degenerative joint disease and can also be used as a tonic and preventative in animals known to be susceptible to joint and bone ailments.

Bar,Berry 30 G 12 Peices Soyjoy

Bar,Berry 30 G 12 Peices Soyjoy
by PHARMAVITE.

INDICATIONS: Soyjoy All Natural Fruit and Soy Bar is made with the goodness of whole soy and dried fruit like raisins, apple, and mango, Soyjoy bars are wholesome nutrition. With 130-140 calories, a SOYJOY bar can satisfy your hunger and keep you energized without overindulging. Made with whole soy and dried fruit. No Artificial Colors, Flavors, Hydrogenated Oils or Gluten. 0 g Trans Fat. 140 Calories. 4 g Protein. Gluten Free. The Benefits of Soyjoy : Soy protein is a complete protein, which means it contains all nine essential amino acids. Nutrient dense whole soybeans are low in saturated fat and are considered a superfood. Whole soy helps promote heart and bone health and other health benefits. Heart Health : Each Soyjoy bar contains 4 grams of soy protein. The U.S. Food and Drug...

The Pocket Primer on the Rheumatic Diseases

The Pocket Primer on the Rheumatic Diseases
by Arthritis Foundation (Author)

A handy guide to the diagnosis and treatment of different types of arthritis and many rheumatic diseases. To be used for spotting symptoms, issuing proper tests, making referrals when necessary and suggesting treatment options.

© 2009 BrightSurf.com