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Weight-loss surgery can cut cancer risk
June 20, 2008Successful bariatric surgery allows morbidly obese patients to lose up to 70 percent of their excess weight and to maintain weight loss. The latest study by Dr. Nicolas Christou of the McGill University Health Centre (MUHC) and McGill University shows that this surgery also decreases the risk of developing cancer by up to 80 percent. Dr. Christou presented his preliminary results yesterday at the 25th Annual Meeting of the American Society for Metabolic & Bariatric Surgery.
The researchers compared 1,035 morbidly obese patients who underwent bariatric surgery at the MUHC between 1986 and 2002 with 5,746 patients with the same weight profile who did not undergo the operation. The number of cancer diagnoses in first group was 85 percent lower for breast cancer and 70 percent lower for colon and pancreatic cancers, and was also distinctly lower for several other types of cancer.
"The relationship between obesity and many forms of cancer is well established," said Dr. Christou. "This is one of the first studies to suggest that bariatric surgery might prevent the risk of cancer for a significant percentage of morbidly obese people."
Obesity affects the body in multiple ways, so a single hypothesis cannot fully explain these results, say the researchers. However, excess body fat is widely thought to be responsible for increased hormone production, a major risk factor for breast and colon cancer. Thus so modifications to the patient's hormonal metabolism due to weight loss might explain the lower incidence of these cancers in patients who underwent surgery.
"Bariatric surgery is an extremely efficient tool in the treatment of morbid obesity and its consequences, and the MUHC is one of Canada's leaders in this field." Dr. Christou said. "We're hoping that these results will help the government and public health authorities realize the importance of this procedure in the fight against the various pathologies associated with obesity."
McGill University Health Centre
Obesity affects the body in multiple ways, so a single hypothesis cannot fully explain these results, say the researchers. However, excess body fat is widely thought to be responsible for increased hormone production, a major risk factor for breast and colon cancer. Thus so modifications to the patient's hormonal metabolism due to weight loss might explain the lower incidence of these cancers in patients who underwent surgery.
"Bariatric surgery is an extremely efficient tool in the treatment of morbid obesity and its consequences, and the MUHC is one of Canada's leaders in this field." Dr. Christou said. "We're hoping that these results will help the government and public health authorities realize the importance of this procedure in the fight against the various pathologies associated with obesity."
McGill University Health Centre
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The use of a robot to assist with the most commonly performed weight-loss surgery appears to significantly lower a patient's risk of developing a rare but serious complication, according to a study published in the most recent edition of the Journal of Robotic Surgery.
Johns Hopkins researchers suppress 'hunger hormone'
Johns Hopkins scientists report success in significantly suppressing levels of the "hunger hormone" ghrelin in pigs using a minimally invasive means of chemically vaporizing the main vessel carrying blood to the top section, or fundus, of the stomach.
Study shows that surgical weight loss does not eliminate obstructive sleep apnea
A study in the August 15 issue of the Journal of Clinical Sleep Medicine shows that surgical weight loss results in an improvement of obstructive sleep apnea (OSA), but most patients continue to have moderate to severe OSA one year after undergoing bariatric surgery.
Bariatric patients have 65% lower chance of complications at top hospitals: HealthGrades study
Bariatric surgery patients treated at highly rated hospitals have, on average, a 65 percent lower chance of experiencing serious complications compared to patients who undergo surgery at poorly rated hospitals according to a study released today by HealthGrades, the nations leading independent healthcare ratings organization.
ASGE issues guidelines on the role of endoscopy in the bariatric surgery patient
The American Society for Gastrointestinal Endoscopy (ASGE) has issued guidelines on the role of endoscopy in the bariatric surgery patient.
Study links gastric bypass surgery to increased risk of kidney stones
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Weight loss after gastric bypass surgery may protect against infection and cancer
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Surgeons complete the first Lap-Band weight-loss surgery in Texas using single incision as entry point
UT Southwestern Medical Center surgeons have completed the first single-incision Lap-Band weight-loss surgery in Texas.
New technique determines that the number of fat cells remains constant in all body types
The radioactive carbon-14 produced by above-ground nuclear testing in the 1950s and '60s has helped researchers determine that the number of fat cells in a human's body, whether lean or obese, is established during the teenage years. Changes in fat mass in adulthood can be attributed mainly to changes in fat cell volume, not an increase in the actual number of fat cells.
Removal of superficial tumours in oesophagus by endoscopy can avoid complete extirpation of this part of the digestive tract
The removal through endoscopy of tumours that affect only the superficial layers of the oesophagus can avoid complete extirpation of this part of the digestive tract.
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