 |
|
Researchers track Lyme disease spirochetes
June 20, 2008Microbiologists at the University of Calgary have demonstrated the first direct visualization of the dissemination of Borrelia burgdorferi, the bacterium that causes Lyme disease. This real-time, three-dimensional look at spirochete dissemination in a living mammalian host is published June 20th in the open-access journal PLoS Pathogens.
Pathogenic spirochetes are a group of bacteria that cause a number of emerging and re-emerging diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme disease. The mechanism by which they disseminate from the blood to target sites is unknown. Direct visualization of these bacteria may yield critical insight into resultant disease processes.
The team therefore set out to directly observe these bacteria at the single-cell level in a living host, using an engineered fluorescent strain of B. burgdorferi as an example bacterium. Using conventional and spinning disk confocal microscopy, the investigators were able to track the movement of the bacteria and the interaction of the bacteria with the vascular wall in mice. They found that vascular escape is a multi-stage process and that spirochete movement appears to play an integral role in dissemination from the blood to target tissue sites.
This use of high-resolution, 3D imaging to visualize the dissemination of a bacterial pathogen in vivo lays the groundwork for a better understanding of the mechanisms by which these and other bacteria disseminate throughout the body to cause disease.
Public Library of Science
This use of high-resolution, 3D imaging to visualize the dissemination of a bacterial pathogen in vivo lays the groundwork for a better understanding of the mechanisms by which these and other bacteria disseminate throughout the body to cause disease.
Public Library of Science
Lyme Disease Current Events and Lyme Disease News RSSGrazing animals help spread plant disease
Researchers have discovered that grazing animals such as deer and rabbits are actually helping to spread plant disease - quadrupling its prevalence in some cases - and encouraging an invasion of annual grasses that threaten more than 20 million acres of native grasslands in California.
Researchers identify cell group key to Lyme disease arthritis
A research team led by the La Jolla Institute for Allergy & Immunology and Albany Medical College has illuminated the important role of natural killer (NK) T cells in Lyme disease, demonstrating that the once little understood white blood cells are central to clearing the bacterial infection and reducing the intensity and duration of arthritis associated with Lyme disease.
New CU-Boulder study shows diversity decreases chances of parasitic disease
A new University of Colorado at Boulder study showing that American toads who pal around with gray tree frogs reduce their chances of parasitic infections known to cause limb malformations has strong implications for the benefits of biodiversity on emerging wildlife diseases.
Study: Bird diversity lessens human exposure to West Nile Virus
A study by biologists at Washington University in St. Louis shows that the more diverse a bird population is in an area, the less chance humans have of exposure to West Nile Virus (WNV).
'Deadly dozen' reports diseases worsened by climate change
Health experts from the Wildlife Conservation Society today released a report that lists 12 pathogens that could spread into new regions as a result of climate change, with potential impacts to both human and wildlife health and global economies.
UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome
A UC Riverside-led team of biomedical scientists has found that a readily available drug called minocycline, used widely to treat acne and skin infections, can be used to treat Fragile X syndrome, the most common inherited cause of mental impairment and the most common cause of autism.
Diversity among bird populations found to reduce threat of West Nile virus
A biologist and undergraduate student have discovered that what's good for an area's bird population is also good for people living nearby.
Drug prevents dangerous tick diseases
Lyme disease is the blight of countryside users but it may be prevented with a single injection, according to research published in the Journal of Medical Microbiology.
University of Pennsylvania Study Reveals Inconspicuous Hosts in the Lyme Disease Epidemic
A study led by a University of Pennsylvania biologist in the tick-infested woods of the Hudson Valley is challenging the widely held belief that mice are the main animal reservoir for Lyme disease in the U.S.
First placebo-controlled study of cognitive impairment due to chronic Lyme disease
Findings from the first placebo-controlled study of chronic cognitive impairment after treated Lyme disease (also known as chronic Lyme encephalopathy) demonstrate that patients report moderate cognitive impairment, physical dysfunction comparable to patients with congestive heart failure, and fatigue comparable to patients with multiple sclerosis.
More Lyme Disease Current Events and Lyme Disease News Articles
 | The Lyme Disease Solution by Kenneth B. Singleton M.D. Lyme disease has become the fastest-growing infectious disease transmitted by ticks (or other vectors) in the United States, but still remains a condition that is frequently misunderstood, overlooked, and misdiagnosed. Written by a leading practitioner of Lyme-aware medicine, this comprehensive guide will reveal to you the facts about this very serious disease - symptoms of which can mimic... |
 | The Lyme Disease Survival Guide: Physical, Lifestyle, and Emotional Strategies for Healing by Connie Strasheim The Lyme Disease Survival Guide, written by health care journalist Connie Strasheim, offers not only a new perspective on Lyme disease diagnosis and treatment, but also much-needed wisdom for dealing with Lyme disease on an emotional, physical, and lifestyle level. Author Connie Strasheim combines sharp knowledge of the nuts and bolts of a Lyme disease treatment campaign with a witty style and... |
 | The Top 10 Lyme Disease Treatments: Defeat Lyme Disease with the Best of Conventional and Alternative Medicine by Bryan Rosner New Lyme Disease treatments are desperately needed. This book provides them. The book identifies ten cutting-edge conventional and alternative treatments and gives practical guidance on integrating them into a comprehensive treatment plan that maximizes therapeutic benefit while minimizing side effects. On the pages of this book you will find the most accurate, current Lyme Disease information... |
 | Beating Lyme: Understanding and Treating This Complex and Often Misdiagnosed Disease by Constance A. Bean, Lesley Ann Fein More than 30 years after it was first diagnosed, Lyme disease remains one of our most misunderstood illnesses. This frequently misdiagnosed infection is spreading at an alarming rate and, if not treated early, can cause debilitating symptoms. More than 1.7 million people in the United States, and others in Europe and Asia, currently have Lyme and are unaware or can't find the right treatment.... |
 | Coping with Lyme Disease: A Practical Guide to Dealing with Diagnosis and Treatment by Denise Lang Lyme disease, transmitted through the bite of a tick, is one of our nation's fastest-growing epidemics. Since Coping with Lyme Disease was first published in 1993, the number of sufferers afflicted by this debilitating condition has grown alarmingly. Every chapter has been thoroughly revised and new information about the long-term neurological effects of Lyme disease and congential and chronic... |
 | Chronic Lyme Disease - Ways to Outsmart a Smart Disease (Spanish, French, Italian, German, Japanese, Russian, Ukrainian, Chinese, Hindi, Tamil, Telugu, ... Gujarati, Bengali and Korean Edition) by Gigi Guthrie M.S.W. This book is a compilation of 18 research-based Lyme treatments, both antibiotic and non-antibiotic, being used today to successfully fight the disease and its associated conditions. Staying ahead of Lyme disease with treatments that are actively reducing symptoms is a way to eradicate the disease and regain a Lyme symptom-free life again. Each treatment is presented in a user-friendly format:... |
| Lyme Disease and Modern Chinese Medicine by Dr. QingCai Zhang, Yale Zhang Lyme disease is the fastest growing infectious disease and it is now epidemical in the Northeast, Middle West, and Northwest regions of the United States. The number of reported cases has doubled in last decade and the infection scale has become larger than HIV. Aside from hepatitis C, Lyme Disease may be the second largest infectious disease in this country. Worldwide, it is also rapidly... | |
 | The Homeopathic Treatment of Lyme Disease by Peter Alex The importance of this work, first published in German in 2005, cannot be overstated. In addition to the clarity of the author's presentation on the usefulness of Homeopathy in the treatment of Lyme disease, we are also gifted with his insight into the nature of epidemic disease in general, our positive interrelationship with bacteria and the trouble that may result whenever we disregard nature's... |
 | Everything You Need to Know About Lyme Disease and Other Tick-Borne Disorders, 2nd Edition by Karen Vanderhoof-Forschner Keep your family safe from tick-borne infections With millions around the world infected–and millions more at risk–Lyme and other tick-related disorders are today’s fastest-growing infectious diseases. And while there has been much progress in combating these illnesses, we are a long way from eliminating them. Early treatment is crucial–and there’s no better way to get informed... |
 | When Antibiotics Fail: Lyme Disease and Rife Machines, with Critical Evaluation of Leading Alternative Therapies by Bryan Rosner There are enough books and websites about what Lyme Disease is and which ticks carry it. But there is very little useful information for people who actually have a case of Lyme Disease that is not responding to conventional antibiotic treatment. Lyme Disease sufferers need to know how to get better, not how to identify a tick. This book is about how experimental frequency devices known as... |
| © 2009 BrightSurf.com |