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MDCT just as accurate as MRI in assessing myocardial infarction in emergency setting
August 05, 2008Multidetector CT (MDCT) is just as accurate as MRI in assessing myocardial infarct size--an important predictor of clinical outcome-- in an emergency setting according to a recent study conducted by researchers in collaboration between the VA Medical Center in San Francisco, CA and the University Claude Bernard in Lyon, France.
"The size of the infarct is one of the most important predictors of long-term left ventricular function in patients with an acute myocardial infarction," said Loic Boussel, MD, lead author of the study. "Imaging of myocardial infarct size is difficult in the emergency setting as the current 'gold standard' methods of delayed enhanced MRI and nuclear medicine techniques are difficult to perform in unstable patients. CT is very easy and quick to perform even at the acute phase so we wanted to find out if it can do the same job as MRI and potentially provide further information," he said.
The study included 19 patients with acute myocardial infarction who underwent delayed enhanced MDCT immediately after coronary angioplasty and underwent delayed enhanced MRI within eight days of angioplasty. The study showed that there was agreement between MRI and MDCT. MDCT had a sensitivity and specificity of 87.6% and 97.7% for the classification of the volume of the myocardial infarct when compared to MRI.
Dr. Boussel noted that MDCT did not require an additional contrast injection and is very practical in an emergency setting.
American Roentgen Ray Society
Dr. Boussel noted that MDCT did not require an additional contrast injection and is very practical in an emergency setting.
American Roentgen Ray Society
Myocardial Infarction Current Events and Myocardial Infarction News RSSVitamin C lowers levels of heart disease biomarker, finds study, adds to debate of health benefits
A new study led by researchers at the University of California, Berkeley, adds to the evidence that vitamin C supplements can lower concentrations of C-reactive protein (CRP), a central biomarker of inflammation that has been shown to be a powerful predictor of heart disease and diabetes.
Low-dose aspirin does not appear to reduce risk of CV events in patients with diabetes
Low-dose aspirin as primary prevention did not appear to significantly reduce the risk of a combined end point of coronary, cerebrovascular and peripheral vascular events in patients with type 2 diabetes, according to a new study in JAMA.
Risk of sudden cardiac death appears increased within 30 days of heart attack
The risk of sudden cardiac death following a heart attack has declined significantly in the past 30 years, although patients appear to be at elevated risk for sudden cardiac death for the first month after having a heart attack, after which time their risk decreases unless they develop heart failure, according to a study in the November 5 issue of JAMA.
Clock-shifts affect risk of heart attack
Adjusting the clocks to summer time on the last Sunday in March increases the risk of myocardial infarction in the following week. In return, putting the clocks back in the autumn reduces the risk, albeit to a lesser extent.
Developing depression after a heart attack increases one's risk of death or readmission
Science has found many links between depression and other serious medical illnesses, such as cancer, stroke, diabetes, and heart disease.
Study reveals embolic neuroprotection system reduces risk of cardiac events
Results of a study on the use of the FiberNet® Embolic Protection System in carotid artery stenting were reported today during the 20th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation (CRF).
Drug-eluting stents more effective, equally as safe as bare metal stents in clinical trial
Late-breaking data from the HORIZONS AMI (Harmonizing Outcomes with RevascularIZatiON and Stents in Acute Myocardial Infarction) trial reveal that after one year, use of a drug-eluting (paclitaxel) stent demonstrated significantly reduced rates of target lesion revascularization (TLR) and binary angiographic restenosis when compared to the use of a bare metal stent in heart attack patients.
HORIZONS AMI will help set guidelines for drug and stent therapy
The HORIZONS AMI clinical trial measuring the safety and efficacy of the use of the medication bivalirudin compared to standard drug therapy - heparin and glycoprotein IIb/IIIa inhibitors -- in heart attack patients who receive angioplasty, found that after 1 year, use of bivalirudin resulted in significantly lower rates of all-cause death, death from cardiac causes, and major bleeding.
Triple antiplatelet therapy appears superior to dual antiplatelet therapy
Results of five research studies and a clinical registry first-report presentation scheduled for the 20th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation (CRF), suggest that triple antiplatelet therapy for patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents achieves greater platelet inhibition than conventional dual antiplatelet therapy.
Men who never smoke live longer, better lives than heavy smokers
Health-related quality of life appears to deteriorate as the number of cigarettes smoked per day increases, even in individuals who subsequently quit smoking, according to a report in the October 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
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