Science Current Events | Science News | Brightsurf.com
 
Email a Friend Send to a friend
Printer Friendly Print Researchers report periodontal disease independently predicts new onset diabetes

Researchers report periodontal disease independently predicts new onset diabetes

August 07, 2008

Periodontal disease may be an independent predictor of incident Type 2 diabetes, according to a study by researchers at Columbia University Mailman School of Public Health. While diabetes has long been believed to be a risk factor for periodontal infections, this is the first study exploring whether the reverse might also be true, that is, if periodontal infections can contribute to the development of diabetes. The full study findings are published in the July 2008 issue of Diabetes Care.

The Mailman School of Public Health researchers studied over 9,000 participants without diabetes from a nationally representative sample of the U.S. population, 817 of whom went on to develop diabetes. They then compared the risk of developing diabetes over the next 20 years between people with varying degrees of periodontal disease and found that individuals with elevated levels of periodontal disease were nearly twice as likely to become diabetic in that 20 year timeframe. These findings remained after extensive multivariable adjustment for potential confounders including, but not limited to, age, smoking, obesity, hypertension, and dietary patterns.




"These data add a new twist to the association and suggest that periodontal disease may be there before diabetes," said Ryan T. Demmer, PhD, MPH, associate research scientist in the Department of Epidemiology at the Mailman School of Public Health and lead author. "We found that over two decades of follow-up, individuals who had periodontal disease were more likely to develop Type 2 diabetes later in life when compared to individuals without periodontal disease."

Also of interest, the researchers found that those study participants who had lost all of their teeth were at intermediate risk for incident diabetes. "This could be suggestive that the people who lost all of their teeth had a history of infection at some point, but subsequently lost their teeth and removed the source of infection," noted Dr. Demmer. "This is particularly interesting as it supports previous research originating from The Oral Infections and Vascular Disease Epidemiology Study (INVEST) which has shown that individuals lacking teeth are at intermediate risk for cardiovascular disease" said Moïse Desvarieux, MD, PhD, director of INVEST, associate professor and Inserm Chair of Excellence in the Department of Epidemiology at the Mailman School and senior author of the paper.

The contributory role of periodontal disease in the development of Type 2 diabetes is potentially of public health importance because of the prevalence of treatable periodontal diseases in the population and the pervasiveness of diabetes-associated morbidity and mortality. However, observes Dr. Demmer, more studies are needed both to determine whether gum disease directly contributes to type 2 diabetes and, from there, that treating the dental problem can prevent diabetes. In addition to Dr. Desvarieux, David R. Jacobs Jr., PhD, professor in the Department of Epidemiology and Community Health at the University of Minnesota, also contributed to the research.

Columbia University's Mailman School of Public Health



Related Periodontal Disease Current Events and Periodontal Disease News Articles Periodontal Disease Current Events and Periodontal Disease News RSS Periodontal Disease Current Events and Periodontal Disease News RSS
New therapeutic options for diabetes-related tissue injury
Diabetes mellitus is a metabolic disorder characterized by altered glucose tolerance and impaired lipid and carbohydrate metabolism, and is associated with a number of complications directly resulting from hyperglycemiainduced inflammation.

Researchers Uncover Higher Prevalence of Periodontal Disease in Rheumatoid Arthritis Patients
Over 1.3 million Americans suffer from rheumatoid arthritis (RA), a chronic, inflammatory disease of the joints. RA is a disabling condition, and can lead to long-term joint damage resulting in persistent pain and loss of function in affected areas.

Tooth loss strongly linked to risk of esophageal, head and neck, and lung cancer
Studying thousands of patients, Japanese researchers have found a strong link between tooth loss and increased risk of three cancers - esophageal, head and neck, and lung. They suggest that preservation of teeth may decrease risk of developing these diseases.

Presence of certain antibodies signals healthier teeth and gums
Antibodies present in people with good oral health could become the first tool for dental professionals to assess a patient's probable response to periodontal disease treatments, say researchers at the University of Michigan.

Turn that Frown Upside Down-Healthy Gums are Something to Smile About
A smile is one of the most universally recognizable facial expressions, helping to depict an individual's happiness, confidence, attractiveness, sociability and sincerity.

Scientists launch first comprehensive database of human oral microbiome
Scientists know more today than ever before about the microbes that inhabit our mouths. They know so much, in fact, that gathering all of the relevant bits of information into one place when designing experiments can be a job in itself.

NYU dental researchers find evidence of periodontal disease leading to gestational diabetes
A study by a New York University dental research team has discovered evidence that pregnant women with periodontal (gum) disease are more likely to develop gestational diabetes mellitus than pregnant women with healthy gums.

Smoking marijuana associated with increased risk for gum disease
Regular use of marijuana (cannabis) in young adulthood is associated with periodontal (gum) disease, according to a study in the February 6 issue of JAMA.

Cannabis indicated as possible risk for gum disease in young people
Young people who are heavy smokers of cannabis may be putting themselves at significant risk for periodontal disease, according to new research.

Heavy marijuana use linked to gum disease
Heavy marijuana use has been found to contribute to gum disease, apart from the known effects that tobacco smoke was already known to have.
More Periodontal Disease Current Events and Periodontal Disease News Articles


Periodontal Disease - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
by ICON Health Publications

In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and...



Periodontal Diseases A Manual of Diagnosis, Treatment and Maintenance
by Hans R. Preus, Lars Laurell

Univ. of Oslo, Norway. Discusses new and established principles for treating periodontal diseases. Introduces several new concepts and ideas and provides guidance in the modern diagnosis of patients with periodontitis. Also describes treatment...



Reversing Gum Disease Naturally: A Holistic Home Care Program
by Sandra Senzon

"Reversing Gum Disease Naturally presents techniques and information so that you can reverse already unhealthy states in your mouth or prevent the onset of gum disease. Sandra Senzon enhances patients' oral health through traditional as well as holistic methods." --Barry Musikant, D.M.D. "This book allows the patient to be an active participant along with healthcare professionals." ...

Periodontal Diseases: Basic Phenomena, Clinical Management, and Occlusal and Restorative Interrelationships
by Ralph Yuodelis, Roy C. Page, Robert H. Johnson

Risk Markers for Oral Diseases: Volume 3, Periodontal Diseases: Markers of Disease Susceptibility and Activity (Risk Markers for Oral Diseases, Vol 3)

Periodontal diseases and dental caries are almost universally prevalent across the world, and oral cancer, the commonest cause of cancer in some developing countries, is a growing problem also in industrial populations. Nevertheless, severe oral disease exists in only a minority of any population, and the three volumes forming Risk Markers for Oral Diseases set out to characterize these at-risk...

An Atlas of the Surgical Management of Periodontal Disease
by Henry M. Goldman, Alan M. Shuman, Gerald A. Isenberg

Pathology of Periodontal Disease (Oxford Medical Publications)
by David M. Williams, Francis J. Hughes, Edward W. Odell, Paula M. Farthing

Periodontal disease affects the mouths of the entire adult population to some degree and causes severe disease in 10 per cent. This is a concise account of the pathological processes involved in periodontal disease, its causes and progression, based on advances in contemporary research. A rational approach to treatment is presented on the basis of these processes. A broad overview of...

Diagnosis and Risk Prediction of Periodontal Diseases (Axelsson, Per, Axelsson Series on Preventive Dentistry, V. 3.)
by Per Axelsson

This volume on periodontal diseases covers topics including: early studies of the disease, the three leading hypotheses regarding underlying causes, and the external and the internal factors that influence the prevalence, onset, and progression of periodontal diseases within individual...

Understanding Periodontal Diseases (Educate Your Patients)
by Joel M. Berns

Formerly called "What is Periodontal Disease?", this booklet has been updated to reflect the changes in the new classification of diseases. Using lay terms and illustrations, the patient booklet explains the pervasive problem of periodontal...

Periodontal disease: Basic phenomena, clinical management, and occlusal and restorative interrelationships
by Saul Schluger

© 2008 BrightSurf.com