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Major study shows significant quality-of-life benefits from HRT
August 22, 2008A major international study of the effects of HRT use on quality of life has shown that HRT use can significantly improve well-being in women with menopausal symptoms such as hot flushes and night sweats. The results of the WISDOM study will be published on BMJ.com on Friday 22 August 2008 (note embargo details above). This study looked at health-related quality of life in 5692 healthy women aged 50-69 in the UK, Australia and New Zealand.
The International Menopause Society notes that the study reported that about 3 out of 4 women, who complained of night sweats and hot flushes, found that these symptoms had vanished after a year of HRT use. Even in women who were well past menopause and did not suffer hot flushes, there was a noted improvement in sleep, sexuality and joint pain as a result of HRT use.
Speaking for the International Menopause Society, Dr Roger Lobo (Columbia University, New York) said
"This report from WISDOM is reassuring that there are real benefits for some women electing to use HRT. While it has been well established that quality-of-life measures are improved in younger symptomatic women, this paper adds some information that even older women may benefit. While some of this information was reported from the WHI, which used the same hormonal regimen, more sensitive instruments were used in WISDOM which was able to show improvements in other measures such as sexual function. While this is important information and is reassuring regarding the benefits of HRT, these findings in isolation are not an indication to initiate hormones in asymptomatic older women for the first time."
Dr David Sturdee (Solihull, UK), President of the International Menopause Society, said:
"This is a significant study, which supports our views on HRT. It shows that HRT can offer real benefits to most women experiencing menopausal symptoms. Our advice remains the same: each woman is an individual, and she needs to discuss what's right for her with her doctor, in the light of her medical history. This study reinforces the benefits of appropriate use."
International Menopause Society
"This report from WISDOM is reassuring that there are real benefits for some women electing to use HRT. While it has been well established that quality-of-life measures are improved in younger symptomatic women, this paper adds some information that even older women may benefit. While some of this information was reported from the WHI, which used the same hormonal regimen, more sensitive instruments were used in WISDOM which was able to show improvements in other measures such as sexual function. While this is important information and is reassuring regarding the benefits of HRT, these findings in isolation are not an indication to initiate hormones in asymptomatic older women for the first time."
Dr David Sturdee (Solihull, UK), President of the International Menopause Society, said:
"This is a significant study, which supports our views on HRT. It shows that HRT can offer real benefits to most women experiencing menopausal symptoms. Our advice remains the same: each woman is an individual, and she needs to discuss what's right for her with her doctor, in the light of her medical history. This study reinforces the benefits of appropriate use."
International Menopause Society
Menopause Current Events and Menopause News RSSMenopause-cardiology consensus statement on cardiovascular disease and on HRT
A menopause-cardiology consensus statement has called for direct action to prevent cardiovascular disease (CVD) in menopausal women. The statement also concludes that there is little evidence of increased CVD risk in taking HRT.
Flaxseed oil and osteoporosis
Animal studies suggest that adding flaxseed oil to the diet could reduce the risk of osteoporosis in post-menopausal women and women with diabetes, according to a report to be published in the International Journal of Food Safety, Nutrition and Public Health.
Fertility procedures need not delay breast cancer treatment for younger women
A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion.
Estrogen therapy likely must be given soon after menopause to provide stroke protection
For estrogen replacement to provide stroke protection, it likely must be given soon after levels drop because of menopause or surgical removal of the ovaries, scientists report in the Journal of Neuroscience.
Are humans still evolving? Absolutely, says a new analysis of a long-term survey of human health
Although advances in medical care have improved standards of living over time, humans aren't entirely sheltered from the forces of natural selection, a new study shows.
Hormone mix could cut breast cancer risk and treat symptoms of menopause
The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk.
Novel, soy-based SE5-OH containing Natural S-equol supplement reduced hot flash frequency by nearly 59 percent
SE5-OH containing Natural S-equol, a novel soy germ-based ingredient in a supplement, improved menopausal symptoms, including significantly reducing hot flash frequency by nearly 59 percent, according to a peer-reviewed study in Japanese women.
Pelvic floor muscle exercises can help manage urinary incontinence in older women
Researchers at Rush University Medical Center have found that a program of pelvic floor muscle exercises, combined with pelvic health education, can be an effective way to manage urinary incontinence in elderly women.
Researchers believe hormone therapy should not be stopped prior to mammograms
Researchers from Boston University School of Medicine (BUSM) are recommending that menopausal women on hormone therapy (HT) continue their treatment prior to having their annual mammogram screenings.
Penn studies point to strategies for reducing painful breast cancer drug side effects
Aromatase inhibitors, the same drugs that have buoyed long-term survival rates among breast cancer patients, also carry side effects including joint pain so severe that many patients discontinue these lifesaving medicines.
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