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Is yakult helpful in the treatment of irritable bowel syndrome?
September 10, 2008SIBO is a common feature in IBS and in fact may be directly related to the genesis of IBS symptoms. An ERBHAL on a lactulose breath test may indicate SIBO. Antibiotics and elemental diets have been shown to be effective in treating SIBO, but the efficacy of probiotics is untested. A pilot study was undertaken to determine the effect of L. strain Shirota (Yakult(R)) on intestinal fermentation patterns of IBS patients. After 6 week of treatment with 1 x 65 mL dose of Yakult(R) daily, 9 of 14 patients (64%) completing the study had reversal of ERBHAL, with the median time of first rise increasing from 45 to 75 min (P = 0.03). Furthermore, symptoms improved in those in whom ERBHAL was corrected. The results indicate that Yakult(R) alters fermentation patterns suggesting a reduction in SIBO. ERBHAL can also indicate rapid small intestinal transit and therefore, in order to confirm the effect of Yakult(R) on SIBO, future studies will include monitoring of transit time in addition to placebo control.
A research article to be published on August 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team was led by Peter Gibson and his colleagues at Monash University, Box Hill Hospital. The pilot trial was undertaken to determine whether a probiotic could have an effect on SIBO. Currently, SIBO is managed by antibiotics and/or elemental diets, the side effects and practicalities of which make them undesirable options. Probiotics may provide a safe alternative. The results of the pilot trial warrant a well powered, double blind, placebo-controlled trial.
The effect of probiotics on SIBO had not previously been investigated, but after taking Yakult(R) daily for 6 wk, there was a significant shift in the time of first rise on the lactulose breath test indicating a reduction in SIBO. If these findings are confirmed by further research, Yakult(R) may be a safe and effective alternative for the management of this patient group.
World Journal of Gastroenterology
World Journal of Gastroenterology
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Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms
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Irritable Bowel Syndrome: A Natural Approach by Rosemary Nicol (Author), M.D. William John Snape Jr. (Foreword) Clearly written with easy-to-understand explanations, this book presents natural solutions for living comfortably with this common ailment. It maintains that thoroughly addressing the causes of IBS—diet and stress—can effectively relieve symptoms without resorting to medication. The authors offer creative dietary alternatives and recipes as well as proven methods for controlling stress—including meditation, yoga, and relaxation exercises. |
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The Irritable Bowel Syndrome Solution: How It's Cured at the IBS Treatment Center by Stephen Wangen (Author) This is the authoritative resource on IBS. If you have IBS, constipation, diarrhea, gas, bloating, indigestion, or chronic abdominal pain, there is a logical reason for your suffering. Written by Dr. Stephen Wangen, the founder and Chief Medical Officer of the IBS Treatment Center, this book explains how your symptoms can be cured. You do not need to eat more fiber, take medications or supplements for the rest of your life, or wonder if you are too stressed. You can actually live you life completely free of IBS. In this book you will discover: · What actually causes IBS. · How to find the cause of your IBS symptoms. · Why most IBS treatments don’t address the causes of IBS. · How to treat IBS once you’ve found the cause. · Where to go for help. · How... |
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I Have IBS...Now What?!!! A Comprehensive Guide for Patients with Irritable Bowel Syndrome by Ashkan Farhadi (Author) The book, I Have IBS, Now What?!!! was written by Dr. Ashkan Farhadi, a leading gastroenterologist based in Chicago. Dr. Farhadi wrote this book as a resource for patients who were diagnosed with Irritable Bowel Syndrome (IBS). This new edition features the most up-to-date information on IBS including new advances in the field. This book compiles real patient questions posed to Dr. Farhadi over years of practice into a first rate guide for patients with IBS and also include the opinion of a group of experts in the field of gastroenterology with a special attention to the psychological and nutritional aspects of this common disorder. |
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