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Which is more accurate, serology test or C14-urea breath test?
September 10, 2008Serology and C14-UBT are the most commonly used non-invasive tests of H. pylori infection. The diagnostic characteristics of the tests depend also on the prevalence of H. pylori infection in the population tested. The diagnostic characteristics of the tests depend also on the prevalence of H. pylori infection in the population tested. Higher prevalences would imply higher sensitivity and lower specificity. There are reports suggesting that there is an association between the level of H. pylori IgG antibodies and the severity of inflammation of the gastric mucosa and also between antibody level and a current peptic ulcer. If so, the level, not only positively or not, of H. pylori IgG antibody tests might be of clinical importance.
A research article to be published on August 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team was led by Dr. Rolv-Ole Lindsetmo and his colleagues in the University of Tromsø in Norway.
They showed by comparing H. pylori IgG antibodies from two peptic ulcer populations that coming from a background population with a high H. pylori prevalence, that the level of IgG antibodies could not be used to predict active peptic ulcer disease and did not show any association with gastric mucosal morphology.
Uncritical use of H. pylori serology will represent a considerable overestimation of H. pylori prevalence in the population tested. A negative H. pylori serology test result is on the other hand very reliable to exclude H. pylori infection and thereby useful in screening purposes.
Dr. Lindsetmo believes that H. pylori serology should be limited to screening and research purposes and that H. pylori serology has limited value in daily clinical practice.
World Journal of Gastroenterology
Uncritical use of H. pylori serology will represent a considerable overestimation of H. pylori prevalence in the population tested. A negative H. pylori serology test result is on the other hand very reliable to exclude H. pylori infection and thereby useful in screening purposes.
Dr. Lindsetmo believes that H. pylori serology should be limited to screening and research purposes and that H. pylori serology has limited value in daily clinical practice.
World Journal of Gastroenterology
In vitro antibody production enables HIV infection detection in window period -- key to safer blood
Researchers in Israel and Kenya have shown that the contribution of variable degrees of immune suppression, either due to existing chronic infections such as parasitemias and/or nutrition, in different populations may influence and prolong the serological-diagnostic window period of HIV.
New research group offers hope to asbestosis sufferers
The Asbestos Research Group, offering hope to sufferers of asbestos-related diseases, was launched at The Wesley Research Institute today.
Bee researchers close in on Colony Collapse Disorder
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CSIRO scientists discover a new bat virus in humans
As reported today in the internationally renowned journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), the discovery was made by a team from CSIRO Livestock Industries' Australian Animal Health Laboratory (AAHL) in Geelong, Victoria, and the National Public Health Laboratory in Selangor, Malaysia.
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Essentials of Immunology and Serology by Delmar Anyone pursuing a career in the medical laboratory will want to have this comprehensive, yet straightforward, text. Essentials of Immunology and Serology doesn't just study the components of the immune system, it covers the way in which these components combine to generate the immune response and how these responses relate to infectious diseases, autoimmunity, tumors, hypersensitivity and transplantation. Covers the application and interpretation of a wide array of medical test kits, unlike other texts that focus only on one outdated procedure. An ideal resource for users pursuing medical lab careers that meets the immunology guidelines of the American Society of Clinical Pathologists. |
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Immunology & Serology in Laboratory Medicine (Immunology & Serology in Laboratory Medicine ( Turgeon)) by Mary Louise Turgeon EdD MT(ASCP) CLS(NCA) (Author) Completely updated, the 4th edition of this classic resource offers the current, comprehensive coverage of immunology you need to stay on the cutting-edge of clinical laboratory science. It provides a solid foundation of knowledge and skills to take you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you'll perform in the lab, including automated techniques. It also explores the medical applications of clinical laboratory science, with information on disorders of infectious and immunologic origin, as well as topics such as transplantation and tumor immunology. Learning objectives, review questions, step-by-step procedures, and case studies help you master key concepts and prepare you to succeed in today's modern laboratory... |
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Fundamental Techniques in Immunology and Serology by Ajit Singh (Author) |
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Study Guide to Accompany Immunology & Serology in Laboratory Medicine by Mary Louise Turgeon (Author) State University of New York, Syracuse. Second edition of an exam review to accompany the text Immunology & Serology in Laboratory Medicine, for students. Includes multiple-choice questions with answers, case studies, references to the textbook, and learning objectives. |
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Stanbio RPR Quicktest, 100/Bx by Stanbio Laboratory Reagin Antibodies Associated with Syphilis · Charcoal flocculation slide test for the determination of Reagin Antibodies associated with Syphilis in serum. · Obtain Qualitative or Semi-Quantitative results . · Controls included - Reactive, Weakly Reactive and Non-Reactive . · Complete test kit includes pipette/stirrers, dispensing needle, dispensing bottle and 18mm circle test cards . · Results in 8 minutes . |
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