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How to differentiate abdominal tuberculosis from lymphomas?
September 24, 2008The incidence of tuberculosis is increasing. Lymphadenopathy is the most common manifestation of abdominal tuberculosis and may, in up to 55% of cases without other evidence of abdominal involvement, be easily confused with lymphomas involving abdominal lymph nodes. Clinical and radiologic differentiation between the two can be challenging. A comparison of CT findings in tuberculosis and lymphoma of the mesenteric lymph nodes has not been reported.
A research article to be published on 28 June 2008, in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Dong P from Weifang Medical University of China has determined that tuberculosis and non-Hodgkin's lymphomas (NHL) mainly affected the lymph nodes in the body and root of the SBM on CT images. Homogeneous enhanced lymph nodes in the body and root of SBM were more often in the NHL (P < 0.05). Homogeneous mixed with peripheral enhanced lymph nodes in the body of SBM were more often in mesenteric TL and TLM (P < 0.05). Peripheral enhanced lymph nodes in the root of SBM were more often in mesenteric TL and TLM (P < 0.01). "Sandwich sign" in the root of SBM was more often in NHL (P < 0.05). The result is helpful in differentiating between tuberculosis and untreated NHL involving the small bowel mesentery (SBM).
Tuberculosis demonstrates a variety of clinical and radiologic features depending on the organ site involved and has a known propensity for dissemination from its primary site. Lymphadenopathy is the most common manifestation of abdominal tuberculosis and may, in up to 55% of cases without other evidence of abdominal involvement, be easily confused with lymphomas involving abdominal lymph nodes. It is important to be familiar with the various radiologic features of tuberculosis and NHL involving the SBM to ensure accurate diagnosis.
The incidence of tuberculosis is increasing. Lymphadenopathy is the most common manifestation of abdominal tuberculosis. Currently, the comparison of CT findings in tuberculosis and lymphomas involving the SBM has not been published in english radiologic literature.
CT manifestations of tuberculosis and NHL mainly affected the lymph nodes in the body and root of the SBM. Homogeneous enhanced lymph nodes in the body and root of SBM were more often in the NHL (P < 0.05). Homogeneous mixed with peripheral enhanced lymph nodes in the body of SBM were more often in mesenteric TL and TLM (P < 0.05). Peripheral enhanced lymph nodes in the root of SBM were more often in mesenteric TL and TLM (P < 0.01). "Sandwich sign" in the root of SBM was more often in NHL (P < 0.05).
In the view of the authors, the CT can show the specific enhancement patterns of lymphadenopathy, sandwich sign and anatomic lymph nodes distribution in tuberculosis and untreated NHL involving the SBM.
This article describes the difference between tuberculosis and NHL involved the SBM, and CT is helpful to the diagnosis and differential diagnosis of the tuberculosis and NHL involving the SBM.
Further research should compare the CT findings of mesenteric tuberculosis with metastatic malignancy and other entities which involved the SBM.
World Journal of Gastroenterology
The incidence of tuberculosis is increasing. Lymphadenopathy is the most common manifestation of abdominal tuberculosis. Currently, the comparison of CT findings in tuberculosis and lymphomas involving the SBM has not been published in english radiologic literature.
CT manifestations of tuberculosis and NHL mainly affected the lymph nodes in the body and root of the SBM. Homogeneous enhanced lymph nodes in the body and root of SBM were more often in the NHL (P < 0.05). Homogeneous mixed with peripheral enhanced lymph nodes in the body of SBM were more often in mesenteric TL and TLM (P < 0.05). Peripheral enhanced lymph nodes in the root of SBM were more often in mesenteric TL and TLM (P < 0.01). "Sandwich sign" in the root of SBM was more often in NHL (P < 0.05).
In the view of the authors, the CT can show the specific enhancement patterns of lymphadenopathy, sandwich sign and anatomic lymph nodes distribution in tuberculosis and untreated NHL involving the SBM.
This article describes the difference between tuberculosis and NHL involved the SBM, and CT is helpful to the diagnosis and differential diagnosis of the tuberculosis and NHL involving the SBM.
Further research should compare the CT findings of mesenteric tuberculosis with metastatic malignancy and other entities which involved the SBM.
World Journal of Gastroenterology
Lymph Node Current Events and Lymph Node News RSSSurvival of head and neck cancer patients is greatly affected by coexisting ailments
Current estimates for head and neck cancer survival are largely inaccurate because they widely disregard many of the most common diseases such patients have in addition to their primary cancer, says Jay Piccirillo, M.D., a head and neck specialist at Washington University School of Medicine in St. Louis, the Siteman Cancer Center and Barnes-Jewish Hospital.
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Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide.
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Cancer immune surveillance is considered to be important in the anti-tumor protection of the host. The growing tumor escapes the immune control under the immunosuppressive conditions.
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Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation
Early-stage breast cancer patients who exhibit limited lymph node involvement may not require post-surgery radiation therapy (RT) when they receive neoadjuvant chemotherapy before a mastectomy, according to researchers from The University of Texas M. D. Anderson Cancer Center.
Which is more accurate on diagnosis of rectal carcinoma?
The depth of transmural tumor invasion along the rectal wall layers and involvement of the regional lymph nodes constitute major factors in the prognosis of rectal cancer.
Study suggests some breast cancer patients facing radiation after a mastectomy may be over-treated
A new study suggests standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects such as lymphedema and pulmonary problems.
Prototype test for predicting clinical outcome for melanoma patients
Investigators from the Melbourne Center of the international Ludwig Institute for Cancer Research (LICR) and Pacific Edge Biotchnology Ltd today reported that they have developed a test to predict whether a patient will progress rapidly from Stage III melanoma to metastatic Stage IV cancer and death.
Checking more lymph nodes linked to cancer patient survival
Why do patients with gastric or pancreatic cancer live longer when they are treated at cancer centers or high-volume hospitals than patients treated at low-volume or community hospitals?
Cancer centers and high-volume hospitals may examine more lymph nodes in cancer patients
Patients with gastric or pancreatic cancer appear to have more lymph nodes examined for the spread of their disease if they are treated at hospitals performing more cancer surgeries or those designated as comprehensive cancer centers.
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