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Which is more accurate on diagnosis of rectal carcinoma?
September 25, 2008The depth of transmural tumor invasion along the rectal wall layers and involvement of the regional lymph nodes constitute major factors in the prognosis of rectal cancer. Therefore accurate preoperative staging of rectal cancer carries a crucial importance in terms of therapy and prognosis. The utility of endorectal ultrasound and pelvic phased-array magnetic resonance imaging has been demonstrated well in the literature. However, studies comparing the diagnostic accuracies of these two techniques are rare.
A research article to be published on 14 June 2008, in the World Journal of Gastroenterology addresses this question. Dr. Halefoglu from Sisli Etfal Training and Research Hospital, Istanbul, Turkey, compared the ability of endorectal ultrasound and pelvic phased-array magnetic resonance imaging for the preoperative staging of rectal carcinoma in a prospective study. 34 patients who had biopsy proven rectal adenocarcinoma were evaluated by both modalities. The imaging results were correlated with the histopathological gold standard evaluations of the surgical specimens.
Phased-array magnetic resonance imaging was found to be slightly superior to endorectal ultrasound in determining the depth of transmural invasion and both techniques have shown similar values in detecting lymph node metastases. Although each technique has been demonstrated as very useful in the preoperative staging of rectal cancer, they can also be used as complementary methods in the accurate staging of rectal cancer.
Both medical professionals and patients are often faced with the dilemma of which technique would be more beneficial in evaluating this increasingly common and at times fatal disease. Dr. Halefoglu resident specialist of Radiology in the Sisli Etfal Training and Research Hospital, Istanbul, Turkey, who also completed his fellowship in the Johns Hopkins Hospital on Body MRI stated that this research could serve as a landmark in enlightening this dilemma.
World Journal of Gastroenterology
Both medical professionals and patients are often faced with the dilemma of which technique would be more beneficial in evaluating this increasingly common and at times fatal disease. Dr. Halefoglu resident specialist of Radiology in the Sisli Etfal Training and Research Hospital, Istanbul, Turkey, who also completed his fellowship in the Johns Hopkins Hospital on Body MRI stated that this research could serve as a landmark in enlightening this dilemma.
World Journal of Gastroenterology
Rectal Cancer Current Events and Rectal Cancer News RSSPreoperative radiation may improve survival rates in advanced rectal cancer patients
Patients treated with radiation prior to surgery for advanced rectal cancer have fewer instances of cancer recurrence and better overall survival rates, according to a recent Geisinger report.
Anti-tumor therapy with endoscopic ultrasound may fight cancer more safely and effectively
The chairman of EUS2008 today announced that investigational research on a therapeutic technique that will allow physicians to directly inject malignant tumors with cancer fighting agents from inside the body will be presented at the 16th International Symposium of Endoscopic Ultrasonography (EUS2008) in San Francisco on September 12-13.
Wide variations in appropriateness of rectal cancer surgery across England
A substantial proportion of rectal cancer patients are receiving inappropriate surgical care, because of wide variations in practice across England, reveals research published ahead of print in the journal Gut.
Regular, long-term aspirin use reduces risk of colorectal cancer
The use of regular, long-term aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk associated with colorectal cancer, according to a study published in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.
Mayo Clinic study points to a possible biomarker for colon cancer in people 50 and under
An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease.
Enzyme eliminated by cancer cells holds promise for cancer treatment
An enzyme that cancer cells eliminate, apparently so they can keep proliferating, may hold clues to more targeted, effective cancer treatment, scientists say.
High-dose inhaled corticosteroid use for COPD could cut risk of lung cancer
Among a group of mostly older male veterans suffering from chronic obstructive pulmonary disease (COPD), an illness that offers a greater susceptibility to lung cancer, researchers found that regular use of high dose inhaled corticosteroids (ICS) lowered the risk of developing lung cancer.
Follow-up endoscopic surveillance in colorectal cancer patients improves survival
Colorectal cancer patients who undergo colonoscopic surveillance during follow-up after surgery experience improved survival, according to a study to be published in the April issue of Clinical Gastroenterology and Hepatology but currently available on-line.
Blood pressure drugs associated with reduced risk of esophageal, pancreatic and colon cancers
Thousands of individuals currently taking angiotension converting enzyme (ACE) inhibitors, a type of medication commonly used to lower blood pressure, may be doing more than treating their hypertension.
Study shows more than half of esophageal cancer patients now survive
In part because the nature of the disease has changed, nearly 50 percent of patients with esophageal cancer that undergo an advanced surgical procedure now survive for five years, not 20 percent as once thought
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