Social class dictates cancer riskSeptember 26, 2008Cervical and lung cancer are more common in poor people while rates of breast cancer and melanoma are higher in the wealthy. A detailed analysis of the incidence of these four different kinds of cancer, carried out on more than 300,000 English cancer patients and published today in the open access journal BMC Cancer, describes the effects of socioeconomic group, region and age. Lorraine Shack at the North West Cancer Intelligence Service and a team of researchers working on behalf of the United Kingdom Association of Cancer Registries used information from all eight English cancer registries from 1998 to 2003. They compared the rates of these four cancers with variations in deprivation. The data were further categorised by the person's age. As Shack describes, "We looked at all invasive cases of lung cancer, cervical cancer, malignant melanoma of the skin and female breast cancer. The deprivation statistics were based on average levels of socioeconomic status in the patient's local area."
Malignant melanoma and breast cancer were most common in more affluent groups. According to the authors, the variations in breast cancer rates may be because "Women from affluent socioeconomic groups are more likely to have their first child at a later age, have fewer children in their lifetime and take hormone replacement therapy. Each of these factors is associated with a slightly higher incidence of breast cancer." The higher incidence of melanoma in the more wealthy groups may be partially explained by holidays abroad and the resulting exposure to UV. However, the authors highlight that sun bed use may have an impact across all socioeconomic groups, particularly in the young, "It is difficult to estimate sun bed use as most salons are private and poorly regulated. However, anecdotal evidence suggests that sun bed use is increasing in England, particularly for teenagers and young adults. Sun parlours tend to be clustered in areas of deprivation." The study also found that the highest rates of lung and cervical cancer occurred in the most deprived groups. The higher incidence of lung cancer in the deprived groups is squarely blamed on smoking, "Smoking is strongly associated with socioeconomic status and over 80% of lung cancer cases can be estimated to be attributable to smoking." Worryingly, the authors found the greatest difference in lung cancer rates between socioeconomic groups in people under the age of 65, possibly suggesting that the more deprived groups continue to smoke while the wealthier groups have quit smoking. The study provides further evidence of the link between wealth and cancer risk. Research such as this has a crucial role to play in tailoring government screening programmes, and other preventative measures, to local needs. BioMed Central | |||||||||||||||||||||
|
Related Cancer Risk Current Events and Cancer Risk News Articles Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene. Gene variations alter risk of esophageal cancer Variations in a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing type of cancer, according to research by scientists at The University of Texas M. D. Anderson Cancer Center. Mayo Clinic Study Finds Risk Assessment Tool Not Reliable Predictor for Some Women at High Risk of Breast Cancer A statistical model commonly used to predict the risk of breast cancer in women was not accurate when used to evaluate women with atypical hyperplasia, according to a new Mayo Clinic study published in the Oct. 14, 2008, issue of the Journal of Clinical Oncology. Migraines associated with lower risk of breast cancer Women who suffer from migraines may take at least some comfort in a recent, first-of-its-kind study that suggests a history of such headaches is associated with a significantly lower risk of breast cancer. Folic acid, B vitamins do not appear to affect cancer risk A daily supplementation combination that included folic acid and vitamin B6 and B12 had no significant effect on the overall risk of cancer, including breast cancer, among women at high risk of cardiovascular disease, according to a study in the November 5 issue of JAMA. Genetic predictors of esophageal cancer identified Researchers have identified 11 genotypes that may increase esophageal cancer risk, according to research published in the November issue of Cancer Prevention Research, a journal of the American Association for Cancer Research. Review examines breast cancer prevention strategies in the United States A new review outlines potential pharmaceutical, dietary, surgical, and other approaches to reducing the risk of breast cancer among women in the United States, and examines the evidence for specific recommendations. Birth control has long-term effect on hormone exposure Researchers at Wake Forest University School of Medicine may be one step closer to understanding why past oral contraceptive use dramatically lowers the risk of ovarian and uterine cancers later in life. Red wine may lower lung cancer risk Moderate consumption of red wine may decrease the risk of lung cancer in men, according to a report in the October issue of Cancer Epidemiology, Biomarkers & Prevention¸ a journal of the American Association for Cancer Research. Study looks at psychological impact of gene test for breast cancer Personal beliefs about inconclusive DNA testing for hereditary breast cancer are associated with cancer-related worry, and such beliefs are an especially strong predictor of whether women had been able to leave the period of DNA-testing behind. More Cancer Risk Current Events and Cancer Risk News Articles |
|||||||||||||||||||||
|
|||||||||||||||||||||
|
|||||||||||||||||||||