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Metabolic syndrome ups colorectal cancer risk
October 06, 2008In a large U.S. population-based study presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology, metabolic syndrome patients had a 75 percent higher risk of colorectal cancer compared to those without metabolic syndrome.
Dr. Donald Garrow and Dr. Mark Delegge of the Medical University of South Carolina in Charleston analyzed data of patients who reported a history of metabolic syndrome and colorectal cancer from the National Health Interview Survey (NHIS), a comprehensive nationally representative study conducted each year by the National Center for Health Statistics.
Metabolic syndrome was defined as having a combination of three common chronic medical conditions: hypertension, diabetes and elevated cholesterol. The risk of colorectal cancer among patients with metabolic syndrome was determined by multivariate logistic regression analysis, controlling for age, race, gender, obesity, smoking and alcohol use.
"Since individuals with the metabolic syndrome have a significantly higher lifetime risk of colorectal cancer, they should closely adhere to published guidelines for colorectal cancer screening," said Dr. Garrow.
About Metabolic Syndrome
Metabolic syndrome refers to a group of risk factors linked to overweight and obesity that increase your chance for heart disease, stroke, diabetes and other serious health problems.
Having just one of these conditions - increased blood pressure, elevated insulin levels, excess body fat around the waist, or abnormal cholesterol levels - contributes to your risk of serious disease. Losing weight, eating a healthy diet, and exercising routinely can help to reduce your risk of metabolic syndrome.
New Education Tools From GI Experts Address Obesity and GI Disease
The American College of Gastroenterology recognizes that the epidemic of obesity is of particular relevance to gastroenterologists because of the clearly documented associations of obesity with a number of gastrointestinal disease risk factors and outcomes, including mortality rates and unfavorable risk profiles.
The ACG has developed new resource tools to help physicians incorporate patient education on the risks overweight and obesity. These educational resources on weight and GI health are available on the ACG Web site at www.acg.gi.org/obesity
American College of Gastroenterology
"Since individuals with the metabolic syndrome have a significantly higher lifetime risk of colorectal cancer, they should closely adhere to published guidelines for colorectal cancer screening," said Dr. Garrow.
About Metabolic Syndrome
Metabolic syndrome refers to a group of risk factors linked to overweight and obesity that increase your chance for heart disease, stroke, diabetes and other serious health problems.
Having just one of these conditions - increased blood pressure, elevated insulin levels, excess body fat around the waist, or abnormal cholesterol levels - contributes to your risk of serious disease. Losing weight, eating a healthy diet, and exercising routinely can help to reduce your risk of metabolic syndrome.
New Education Tools From GI Experts Address Obesity and GI Disease
The American College of Gastroenterology recognizes that the epidemic of obesity is of particular relevance to gastroenterologists because of the clearly documented associations of obesity with a number of gastrointestinal disease risk factors and outcomes, including mortality rates and unfavorable risk profiles.
The ACG has developed new resource tools to help physicians incorporate patient education on the risks overweight and obesity. These educational resources on weight and GI health are available on the ACG Web site at www.acg.gi.org/obesity
American College of Gastroenterology
Metabolic Syndrome Current Events and Metabolic Syndrome News RSSU of I study: Fructose metabolism more complicated than was thought
A new University of Illinois study suggests that we may pay a price for ingesting too much fructose. According to lead author Manabu Nakamura, dietary fructose affects a wide range of genes in the liver that had not previously been identified.
Exercise helps overweight children reduce anger expression
Regular exercise seems to reduce anger expression in overweight but otherwise healthy children, researchers said.
Systems biology brings hope of speeding up drug development
Almost every day brings news of an apparent breakthrough against cancer, infectious diseases, or metabolic conditions like diabetes, but these rarely translate into effective therapies or drugs, and even if they do clinical development usually takes well over a decade.
Bad cholesterol inhibits the breakdown of peripheral fat
he so called bad cholesterol (LDL) inhibits the breakdown of fat in cells of peripheral deposits, according to a study from the Swedish medical university Karolinska Institutet. The discovery reveals a novel function of LDL as a regulator of fat turnover besides its well-established detrimental effects in promoting atherosclerosis.
Coping and copulation behavior may help calculate diabetes risk
Discussion of a man's background, attitude, and sexual history isn't just the fodder of Sex and The City episodes - in the future, it could also be a way of evaluating his risk of diabetes.
Association found between severe obstructive sleep apnea
A study in the October 15 issue of the Journal of Clinical Sleep Medicine shows that unrelated to obesity, people with severe SDBs consume a more unhealthy diet, which may be a factor contributing to greater cardiovascular morbidity and mortality. These findings were most evident among women.
Newly identified cells make fat
To understand where fat comes from, you have to start with a skinny mouse. By using such a creature, and observing the growth of fat after injections of different kinds of immature cells, scientists at the Howard Hughes Medical Institute and Rockefeller University have discovered an important fat precursor cell that may in time explain how changes in the numbers of fat cells might increase and lead to obesity.
Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
A healthy body stores fat in the form of so-called triglycerides in specialized fatty tissue as an energy reserve. Under certain conditions the delicate balance of the lipid metabolism gets out of control and fat is accumulated in the liver, leading to the dreaded fatty liver.
Bisphenol A linked to metabolic syndrome in human tissue
New research from the University of Cincinnati (UC) implicates the primary chemical used to produce hard plastics-bisphenol A (BPA)-as a risk factor for metabolic syndrome and its consequences.
Risks and benefits of antipsychotics in children and adolescents
Many of the psychiatric disorders observed in adults have their onset in childhood or adolescence. In fact some studies show that at least 20% of children and adolescents will fulfil a diagnostic criterion for a mental disorder before reaching adulthood.
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