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New studies examine the effectiveness of probiotics in IBS
October 06, 2008Several studies presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando highlight the safety and efficacy of probiotics in improving symptoms and normalizing bowel movement frequency in patients suffering from constipation or diarrhea related to Irritable Bowel Syndrome (IBS).
New Systematic Review of Probiotics in IBS
A systematic review of the efficacy of probiotics in IBS that included 19 randomized controlled trials in 1,628 IBS patients found that "probiotics are effective in IBS, but we do not have enough information to be sure whether there is one probiotic that is particularly effective or whether combinations of probiotics are required," according to Dr. Paul Moayyedi, the study's lead researcher. Moayyedi and co-investigators at Mayo Clinic in Jacksonville, FL and Rochester, MN; McMaster University in Ontario, Canada; University College in Cork, Ireland and Montefiore Medical Center in New York City, conducted this meta-analysis presented at the ACG Annual Scientific Meeting in Orlando.
Multi-Strain Probiotic for IBS Patients with Diarrhea
Dr. Gerald Friedman of The Mount Sinai School of Medicine in New York and co-investigator Greg Biancone conducted a multi-center analysis to determine if a multi-strain probiotic was effective in reducing the frequency of diarrhea in 84 IBS patients (IBS-D). In this small study, a multi-strain probiotic administered daily for 28 days normalized bowel habits in IBS patients compared to those who received the placebo. The average number of daily diarrheal episodes in the probiotic group significantly decreased from day 1 to day 28 compared to slight decreases in the placebo group during the same period.
Analysis of Probiotics in Children with IBS
In a placebo-controlled, double-blinded, cross-over study conducted at seven pediatric GI centers in the United States, Italy, and India, Dr. Stefano Guandalini of the University of Chicago and his research team randomly assigned 59 pediatric IBS patients to receive either a probiotic agent (VSL#3®) or a placebo for six weeks. At the end of six weeks, patients switched to the other arm of the study and underwent six more weeks of treatment. Patients filled out a questionnaire to assess their symptoms and overall quality of life before and after treatment. Researchers found the probiotic agent was safe and significantly more effective than the placebo in alleviating IBS-related symptoms (abdominal pain/discomfort, bloating, stool dysfunction) in children and teenagers.
American College of Gastroenterology
Multi-Strain Probiotic for IBS Patients with Diarrhea
Dr. Gerald Friedman of The Mount Sinai School of Medicine in New York and co-investigator Greg Biancone conducted a multi-center analysis to determine if a multi-strain probiotic was effective in reducing the frequency of diarrhea in 84 IBS patients (IBS-D). In this small study, a multi-strain probiotic administered daily for 28 days normalized bowel habits in IBS patients compared to those who received the placebo. The average number of daily diarrheal episodes in the probiotic group significantly decreased from day 1 to day 28 compared to slight decreases in the placebo group during the same period.
Analysis of Probiotics in Children with IBS
In a placebo-controlled, double-blinded, cross-over study conducted at seven pediatric GI centers in the United States, Italy, and India, Dr. Stefano Guandalini of the University of Chicago and his research team randomly assigned 59 pediatric IBS patients to receive either a probiotic agent (VSL#3®) or a placebo for six weeks. At the end of six weeks, patients switched to the other arm of the study and underwent six more weeks of treatment. Patients filled out a questionnaire to assess their symptoms and overall quality of life before and after treatment. Researchers found the probiotic agent was safe and significantly more effective than the placebo in alleviating IBS-related symptoms (abdominal pain/discomfort, bloating, stool dysfunction) in children and teenagers.
American College of Gastroenterology
Probiotics Current Events and Probiotics News RSSEinstein researchers find convincing evidence that probiotics are effective
Up to one in five people on antibiotics stop taking their full course of antibiotic therapy due to diarrhea. Physicians could help patients avoid this problem by prescribing probiotics, according to a study by researchers at Albert Einstein College of Medicine of Yeshiva University published in American Family Physician.
Pregnant women with asthma can be more confident about some medicines
Women can usually keep using the same asthma drugs they were using before they got pregnant. Budesonide sprays are the best studied and can be regarded as safe.
Pregnant women with asthma can be more confident about some medicines
Women can usually keep using the same asthma drugs they were using before they got pregnant. Budesonide sprays are the best studied and can be regarded as safe.
Friendly bacteria reduce hospital infections
A probiotic bacterium, Lactobacillus plantarum 299, has been used to out-compete the dangerous bacteria that cause respiratory illness in ventilated patients.
Is yakult helpful in the treatment of irritable bowel syndrome?
SIBO is a common feature in IBS and in fact may be directly related to the genesis of IBS symptoms. An ERBHAL on a lactulose breath test may indicate SIBO.
New study shows health benefits of probiotic could extend to the entire body
Data from a recent study demonstrate the anti-inflammatory and pathogen protection benefits of Bifidobacterium infantis 35624 a probiotic bacterial strain of human origin.
The latest research on allergies: Specific immunotherapy can help
he German Institute for Quality and Efficiency in Health Care has assessed recent evidence on allergies. It found that the once controversial immune therapy against allergy symptoms can definitely help many people with allergies.
Study finds healthy intestinal bacteria within chicken eggs: Finding could have important implications for poultry industry, food safety
The conventional wisdom among scientists has long been that birds acquire the intestinal bacteria that are necessary for good health from their environment, but a new University of Georgia study finds that chickens are actually born with those bacteria.
Report raises C. diff concerns; yeast-based probiotic shown to help significantly reduce recurrence
C. diff-associated disease (CDAD), otherwise known as severe intestinal disease brought on by the Clostridium difficile (C. diff) pathogen, has been the subject of heightened concern in the medical community.
Do bacterial combinations result in enhanced cytokine production? No!
Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have been used for the prevention and treatment of a diverse range of disorders.
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