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Vitamin D deficiency may be more common in Parkinson's disease patients
October 14, 2008Individuals with Parkinson's disease appear more likely to be vitamin D deficient than healthy adults of the same age or patients with Alzheimer's disease, according to a report in the October issue of Archives of Neurology, one of the JAMA/Archives journals.
"Vitamin D is important for maintaining many physiologic functions, and vitamin D deficiency is associated with increased risk of disease," according to background information in the article. "Patients with chronic neurodegenerative diseases frequently have many risk factors for vitamin D insufficiency," including advancing age, obesity, avoidance of sun exposure, residence in northerly latitudes and having darker skin.
Marian L. Evatt, M.D., M.S., and colleagues at the Emory University School of Medicine, Atlanta, compared vitamin D levels of 100 patients with Parkinson's disease to vitamin D levels of 97 Alzheimer's disease patients and 99 healthy individuals matched for age, sex, race, genotype and geographic location.
"Significantly more patients with Parkinson's disease (55 percent) had insufficient vitamin D than did controls (36 percent) or patients with Alzheimer's disease (41 percent)," the authors write. The average vitamin D concentration in the group with Parkinson's disease was considerably lower than the Alzheimer's disease and healthy groups (31.9 nanograms per milliliter vs. 34.8 nanograms per milliliter and 37 nanograms per milliliter, respectively).
"These findings support the previously suggested need for further studies to assess what contribution a low 25(OH)D [a measure of blood vitamin D levels] concentration adds to the risk of developing Parkinson's disease (vs. other neurodegenerative disorders) and to determine whether correction of vitamin D insufficiency and deficiency will improve motor or non-motor symptoms in Parkinson's disease," the authors conclude.
"Finally, the finding of a high incidence of vitamin D deficiency in the Parkinson's disease and other cohorts highlights the importance of routinely checking the level of 25(OH)D, particularly in elderly patients, since deficiency is strongly correlated with a higher incidence of osteoporosis, falls and hip fractures and has been associated with a higher incidence of several forms of cancer and autoimmune disorders."
JAMA and Archives Journals
"Significantly more patients with Parkinson's disease (55 percent) had insufficient vitamin D than did controls (36 percent) or patients with Alzheimer's disease (41 percent)," the authors write. The average vitamin D concentration in the group with Parkinson's disease was considerably lower than the Alzheimer's disease and healthy groups (31.9 nanograms per milliliter vs. 34.8 nanograms per milliliter and 37 nanograms per milliliter, respectively).
"These findings support the previously suggested need for further studies to assess what contribution a low 25(OH)D [a measure of blood vitamin D levels] concentration adds to the risk of developing Parkinson's disease (vs. other neurodegenerative disorders) and to determine whether correction of vitamin D insufficiency and deficiency will improve motor or non-motor symptoms in Parkinson's disease," the authors conclude.
"Finally, the finding of a high incidence of vitamin D deficiency in the Parkinson's disease and other cohorts highlights the importance of routinely checking the level of 25(OH)D, particularly in elderly patients, since deficiency is strongly correlated with a higher incidence of osteoporosis, falls and hip fractures and has been associated with a higher incidence of several forms of cancer and autoimmune disorders."
JAMA and Archives Journals
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New study links vitamin D deficiency to cardiovascular disease and death
While mothers have known that feeding their kids milk builds strong bones, a new study by researchers at the Heart Institute at Intermountain Medical Center in Salt Lake City suggests that Vitamin D contributes to a strong and healthy heart as well - and that inadequate levels of the vitamin may significantly increase a person's risk of stroke, heart disease, and death, even among people who've never had heart disease.
Latest analysis confirms suboptimal vitamin D levels in millions of US children
Millions of children in the United States between the ages of 1 and 11 may suffer from suboptimal levels of vitamin D, according to a large nationally representative study published in the November issue of Pediatrics, accompanied by an editorial.
Insufficient levels of vitamin D puts elderly at increased risk of dying from heart disease
A new study by researchers at the University of Colorado Denver and Massachusetts General Hospital (MGH) shows vitamin D plays a vital role in reducing the risk of death associated with older age.
Key feature of immune system survived in humans, other primates for 60 million years
A new study has concluded that one key part of the immune system, the ability of vitamin D to regulate anti-bactericidal proteins, is so important that is has been conserved through almost 60 million years of evolution and is shared only by primates, including humans - but no other known animal species.
Metabolic bone disease in cirrhosis patients
Long-standing liver disease has long been recognized to result in fragile bones with increased risk of fractures. In various international studies, the overall incidence has varied from 11% to 48%, with a fracture rate of 3%-44%.
Millions of US children low in vitamin D
Seven out of ten U.S. children have low levels of vitamin D, raising their risk of bone and heart disease, according to a study of over 6,000 children by researchers at Albert Einstein College of Medicine of Yeshiva University.
Children's Hospital Oakland scientist characterizes new syndrome of allergy, apraxia, malabsorption
A landmark study conducted by Children's Hospital & Research Center Oakland is the first to reveal a new syndrome in children that presents with a combination of allergy, apraxia and malabsorption. Autism spectrum disorders were variably present.
Winter- and spring-onset RA patients have worse 6 month outcomes than those with summer onset
When a patient's first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7], p=0.0255).
Is vitamin D deficiency linked to Alzheimer's disease and vascular dementia?
There are several risk factors for the development of Alzheimer's disease and vascular dementia. Based on an increasing number of studies linking these risk factors with Vitamin D deficiency.
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Nutristart Quick D Organic Liquid Vitamin D 12.5ml 1000iu 365 Day Supply by Nutristart Quick D is made with some of the most stable ingredients available. The base contains vitamin C (Ascorbyl Palmitate), Vitamin E (Mixed Topherols) and organic Sunflower oil. Most liquid vitamin D products use an undefined generic vegetable oil for their base, which may contain various possible allergens. Some even use fish oil, which can turn rancid (and spoil your breath!). Nutristart never turns rancid - an important consideration for a year's supply. This is a seriously potent formula, giving you a full 1000 IU of Vitamin D in each and every drop! That means this little bottle will take care of your Vitamin D needs for a FULL YEAR! Don't be fooled by lower-content liquid vitamin D supplements that advertise one drop per day, yet only give you 200 IU or so in each drop. Nutristart... |
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