Large hormone dose may reduce risk of post-traumatic stress disorderOctober 28, 2008A new study by Ben-Gurion University of the Negev (BGU) researchers found that a high dose of cortisone could help reduce the risk of post-traumatic stress disorder (PTSD). The article appears in Biological Psychiatry, Volume 64, Issue 8 (October 15, 2008), pages 708-717. In an animal model of PTSD, high doses of a cortisol-related substance, corticosterone, prevented negative consequences of stress exposure, including increased startle response and behavioral freezing when exposed to reminders of the stress. Cortisol is secreted into the blood stream through the adrenal glands, which are active when the body responds to stress. It is known as "the stress hormone" because it is also secreted in higher levels during the body's "fight or flight" response to stress, and is responsible for several stress-related changes in the body. According to Dr. Hagit Cohen of the Anxiety and Stress Research Unit at the Faculty of Health Sciences, Ben-Gurion University of the Negev, "A single intervention with high-dose corticosterone immediately after exposure to a psychogenic stressor was highly effective in reducing the incidence of PTSD-like behaviors and improved the resilience to subsequent trauma-cue exposure in an innovative controlled prospective animal study." "Single high-dose corticosteroid treatment may thus be worthy of clinical investigation as a possible avenue for early pharmaco-therapeutic intervention in the acute phase, aimed at prevention of chronic stress-related disorders, such as PTSD," Cohen explains. "In this sense, it brings treatment of PTSD to a new era - an era of secondary prevention, an era of the golden hours." American Associates, Ben-Gurion University of the Negev |
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| Related Post-traumatic Current Events and Post-traumatic News Articles New UAB Study Sheds Light on Brain's Response to Distress, Unexpected Events In a new study, psychologists at the University of Alabama at Birmingham (UAB) are able to see in detail for the first time how various regions of the human brain respond when people experience an unexpected or traumatic event. Psychiatric impact of torture could be amplified by head injury Depression and other emotional symptoms in survivors of torture and other traumatic experiences may be exacerbated by the effects of head injuries, according to a study from the Harvard Program in Refugee Trauma (HPRT), based in the Massachusetts General Hospital (MGH) Department of Psychiatry. Use of cannabinoids (marijuana) could help post-traumatic stress disorder patients Use of cannabinoids (marijuana) could assist in the treatment of post-traumatic stress disorder patients. This is exposed in a new study carried out at the Learning and Memory Lab in the University of Haifa's Department of Psychology. MU Researchers Use Computational Models to Study Fear The brain is a complex system made of billions of neurons and thousands of connections that relate to every human feeling, including one of the strongest emotions, fear. Researchers unravel mystery behind long-lasting memories A new study by researchers at Wake Forest University School of Medicine may reveal how long-lasting memories form in the brain. PTSD associated with higher Alzheimer's/dementia risk; moderate alcohol consumption may lower it Though discoveries about Alzheimer's disease risk factors are often in the news, adults do not know about the relationship between Alzheimer's disease risk and heart health, nor that physical activity can be protective against dementia. CU-Boulder study shows brain's immune system may cause chronic seizures Chronic seizures caused by traumatic head injuries may result from chemicals released by the brain's immune system attempting to repair the injured site. Neuroscience research could benefit US Army, yet challenge traditional approaches Advances in neuroscience research could benefit the Army, particularly in areas of soldier training and education. However, an emerging trend of using individual variability in neural processes such as cognition, stress response, and decision making to improve group performance is likely to challenge conventional approaches to training and educating soldiers. Witnessing violence affects kids' health School-aged children who witness violence in urban communities show symptoms of post-traumatic stress. They also suffer physiological effects with a disruption to their normal cortisol production pattern during the day, which may have long-term negative effects on their health. Controlling our brain's perception of emotional events Research performed by Nicole Lauzon and Dr. Steven Laviolette of the Schulich School of Medicine & Dentistry at The University of Western Ontario has found key processes in the brain that control the emotional significance of our experiences and how we form memories of them. More Post-traumatic Current Events and Post-traumatic News Articles |
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