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Review examines breast cancer prevention strategies in the United States
November 05, 2008A new review outlines potential pharmaceutical, dietary, surgical, and other approaches to reducing the risk of breast cancer among women in the United States, and examines the evidence for specific recommendations.
The review says risk reduction strategies for women at average risk of breast cancer should focus primarily on lifestyle factors. Among the recommendations: aside from following general dietary recommendations for healthy eating, there is no clear evidence that specific dietary components can effectively reduce breast cancer risk; while all women should be advised to moderate alcohol use, women at increased risk of breast cancer should moderate alcohol intake or even avoid alcohol; women should maintain a healthy body weight, since gaining over 20 pounds during adulthood has been reported to result in an increased risk of breast cancer.
The authors say use of pharmacotherapy to reduce the risk should be individualized to each patient after a thorough discussion of risks and benefits as part of a shared decision-making process.
"While decreases in both breast cancer incidence and breast cancer mortality have been apparent in recent years, the societal and economic impact of this malignancy continues to be huge," write the authors. "Although a constellation of breast cancer risk factors has been identified, many of these are not easily modified. Further, many women worry about the potential impact of a breast cancer diagnosis on themselves and their families. As a result, interest in strategies to prevent breast cancer remains strong."
American Cancer Society
"While decreases in both breast cancer incidence and breast cancer mortality have been apparent in recent years, the societal and economic impact of this malignancy continues to be huge," write the authors. "Although a constellation of breast cancer risk factors has been identified, many of these are not easily modified. Further, many women worry about the potential impact of a breast cancer diagnosis on themselves and their families. As a result, interest in strategies to prevent breast cancer remains strong."
American Cancer Society
Breast Cancer Current Events and Breast Cancer News RSSMenopause-cardiology consensus statement on cardiovascular disease and on HRT
A menopause-cardiology consensus statement has called for direct action to prevent cardiovascular disease (CVD) in menopausal women. The statement also concludes that there is little evidence of increased CVD risk in taking HRT.
Researchers Identify Role of Gene in Tumor Development, Growth and Progression
Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine researchers have identified a gene that may play a pivotal role in two processes that are essential for tumor development, growth and progression to metastasis.
UCLA researchers create 'fly paper' to capture circulating cancer cells
Just as fly paper captures insects, an innovative new device with nano-sized features developed by researchers at UCLA is able to grab cancer cells in the blood that have broken off from a tumor.
Fertility procedures need not delay breast cancer treatment for younger women
A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion.
Coffee break: Compound brewing new research in colon, breast cancer
A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists.
Drugs to treat anemia in cancer patients linked to thromboembolism
Medications frequently given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., co-director of the breast cancer program at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center.
Discovery in worms by Queen's researchers points to more targeted cancer treatment
Researchers at Queen's University have found a link between two genes involved in cancer formation in humans, by examining the genes in worms. The groundbreaking discovery provides a foundation for how tumor-forming genes interact, and may offer a drug target for cancer treatment.
FDA approved leukemia drugs shows promise in ovarian cancer cells
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found.
Carnegie Mellon researchers link health-care debate to risk of dying in US and Europe
The current health care debate in the United States is complicated. Trade-offs between heath care expenditures, lifestyle choices and life expectancy have been suggested but seldom clearly demonstrated.
Scientists uncover new key to the puzzle of hormone therapy and breast cancer
The use of postmenopausal hormone therapy has decreased over time in the United States, which researchers suggest may play a key role in the declining rate of atypical ductal hyperplasia, a known risk factor for breast cancer.
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