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Study shows pine bark reduces jetlag
November 06, 2008Pycnogenol cut jetlag symptoms in half for passengers taking 7- to 9-hour flights
A new study published in the journal of Minerva Cardioangiologica reveals Pycnogenol, pine bark extract from the French maritime pine tree, reduces jetlag in passengers by nearly 50 percent. The two-part study, consisting of a brain CT scan and a scoring system, showed Pycnogenol lowered symptoms of jetlag such as fatigue, headaches, insomnia and brain edema (swelling) in both healthy individuals and hypertensive patients. Passengers also experienced minimal lower leg edema, a common condition associated with long flights.
Jetlag, also called desynchronosis, is a temporary disorder that causes a variety of temporary mental and physical impairments as a result of air travel across time zones - common in flights to Asia and Europe, but also observed in travelers between West and East coast. It is caused due to the body's inability to immediately adjust to the time in a different zone while travelling. As the body struggles to cope with the new schedule, temporary conditions such as insomnia, fatigue, irritability and an impaired ability to concentrate may set in.
"This study could not have come at a better time for the upcoming holiday travel season," said Dr. Gianni Belcaro, a lead researcher of the study. Belcaro attributes Pycnogenol's combined activities for better circulation and antioxidant potency to such remarkable results. "Previous Pycnogenol flight studies have shown a reduction in jetlag; however this was the first study to solely focus on the condition."
The study, conducted at the G. D'Annunzio University in Pescara, Italy, consisted of 133 passengers who took flights that were seven to nine hours in length. Fifty mg of oral Pycnogenol was administered three times daily, for seven days, starting two days prior to the flight.
Patients in the first part of the study were evaluated with a rating scale consisting of a scoring system. Thirty-eight Pycnogenol-treated and 30 control patients were rated on the most common complaints of jetlag: dehydration and loss of appetite; headaches and/or sinus irritation; fatigue; disorientation and/or grogginess; nausea and/or upset stomach; insomnia and/or highly irregular sleep patterns; irritability; irrational behavior; alternation in mental performance (easy crossword); alternations in general wellbeing; hours of duration of any signs/symptoms; and nights of altered/disturbed sleep. Observations were measured and taken within 48 hours after the end of the flights. Results showed a significantly lower score (56 percent) in the Pycnogenol group for all items rated, amounting in a significant reduction of all jetlag signs and symptoms. Moreover, symptoms lasted only for an average of 18.2 hours in the Pycnogenol group as compared to 39.3 hours in the control group.
In a second group of flight passengers, a brain CT scan was performed after the flight in order to assess brain alterations after flights. The study consisted of 34 Pycnogenol-treated patients and 31 controlled patients. Jetlag symptoms were evaluated using a rating scale providing scores according to the severity. The first observation was performed within 28 hours from the end of the flight. Sleep alterations, short-term memory alterations, disorientation, neurological signs/symptoms of instability, anxiety, minor cardiac alterations (heart rate, blood pressure), lower limb swelling, fatigue and other, a-specific signs/symptoms (cramps, joints/muscular pain, blurred vision, vertigo, mild sickness, increase in body temperature, appetite loss, headache, mild tongue swelling) were all significantly lower by in average 61.5% in the Pycnogenol group compared to the untreated control group.
"This is the first study describing diffuse subliminal swellings of the brain after long haul flights, which we found to be reduced to less than half in the Pycnogenol group," said Dr. Belcaro
"I'm encouraged by the results of the study as Pycnogenol was effective in preventing jetlag related effects without any side-effects," said Dr. Belcaro. While more research needs to be conducted on this topic, Pycnogenol is emerging as natural, yet safe option for long distance travelers.
Pycnogenol has been shown to be beneficial for flight travel in previous studies pertaining to edema, deep vein thrombosis (DVT) and blood circulation improvement. A study published in Clinical Applied Thrombosis/Hemostasis recorded passengers supplementing with Pycnogenol on long distance flights lasting 7-12 hours were significantly protected from thrombotic events, complications resulting from deep vein thrombosis (DVT) and superficial vein thrombosis (SVT). In 2005, a study published in Clinical and Applied Thrombosis/Hemostasis showed Pycnogenol to be effective in reducing leg and ankle swelling (edema) during long airplane flights lasting seven to 12 hours.
MWW Group
"This study could not have come at a better time for the upcoming holiday travel season," said Dr. Gianni Belcaro, a lead researcher of the study. Belcaro attributes Pycnogenol's combined activities for better circulation and antioxidant potency to such remarkable results. "Previous Pycnogenol flight studies have shown a reduction in jetlag; however this was the first study to solely focus on the condition."
The study, conducted at the G. D'Annunzio University in Pescara, Italy, consisted of 133 passengers who took flights that were seven to nine hours in length. Fifty mg of oral Pycnogenol was administered three times daily, for seven days, starting two days prior to the flight.
Patients in the first part of the study were evaluated with a rating scale consisting of a scoring system. Thirty-eight Pycnogenol-treated and 30 control patients were rated on the most common complaints of jetlag: dehydration and loss of appetite; headaches and/or sinus irritation; fatigue; disorientation and/or grogginess; nausea and/or upset stomach; insomnia and/or highly irregular sleep patterns; irritability; irrational behavior; alternation in mental performance (easy crossword); alternations in general wellbeing; hours of duration of any signs/symptoms; and nights of altered/disturbed sleep. Observations were measured and taken within 48 hours after the end of the flights. Results showed a significantly lower score (56 percent) in the Pycnogenol group for all items rated, amounting in a significant reduction of all jetlag signs and symptoms. Moreover, symptoms lasted only for an average of 18.2 hours in the Pycnogenol group as compared to 39.3 hours in the control group.
In a second group of flight passengers, a brain CT scan was performed after the flight in order to assess brain alterations after flights. The study consisted of 34 Pycnogenol-treated patients and 31 controlled patients. Jetlag symptoms were evaluated using a rating scale providing scores according to the severity. The first observation was performed within 28 hours from the end of the flight. Sleep alterations, short-term memory alterations, disorientation, neurological signs/symptoms of instability, anxiety, minor cardiac alterations (heart rate, blood pressure), lower limb swelling, fatigue and other, a-specific signs/symptoms (cramps, joints/muscular pain, blurred vision, vertigo, mild sickness, increase in body temperature, appetite loss, headache, mild tongue swelling) were all significantly lower by in average 61.5% in the Pycnogenol group compared to the untreated control group.
"This is the first study describing diffuse subliminal swellings of the brain after long haul flights, which we found to be reduced to less than half in the Pycnogenol group," said Dr. Belcaro
"I'm encouraged by the results of the study as Pycnogenol was effective in preventing jetlag related effects without any side-effects," said Dr. Belcaro. While more research needs to be conducted on this topic, Pycnogenol is emerging as natural, yet safe option for long distance travelers.
Pycnogenol has been shown to be beneficial for flight travel in previous studies pertaining to edema, deep vein thrombosis (DVT) and blood circulation improvement. A study published in Clinical Applied Thrombosis/Hemostasis recorded passengers supplementing with Pycnogenol on long distance flights lasting 7-12 hours were significantly protected from thrombotic events, complications resulting from deep vein thrombosis (DVT) and superficial vein thrombosis (SVT). In 2005, a study published in Clinical and Applied Thrombosis/Hemostasis showed Pycnogenol to be effective in reducing leg and ankle swelling (edema) during long airplane flights lasting seven to 12 hours.
MWW Group
Pycnogenol Current Events and Pycnogenol News RSSStudy demonstrates the anti-inflammatory properties of pine bark extract
A recent study published in International Immunopharmacology, reveals why Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, is effective for reducing inflammation and soothing pain associated with various health problems.
Pine bark reduces inflammatory marker CRP in osteoarthritis
Osteoarthritis (OA), a type of arthritis caused by the breakdown and loss of cartilage, affects more than 20 million Americans.
Study shows pine bark naturally reduces knee osteoarthritis
According to the Center for Disease Control (CDC), osteoarthritis, the most common type of arthritis, is on the rise. A new study published in the August journal of Phytotherapy Research, reveals Pycnogenol, bark extract from the French maritime pine tree, reduced overall knee osteoarthritis (OA) symptoms by 20.9 percent and lowered pain by 40.3 percent.
Study shows pine bark naturally reduces cardiovascular risk factors in diabetics
A new study published in the May 2008 (volume 8, issue 25) edition of the journal of Nutrition Research shows Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, reduces blood sugar in type II diabetes patients, allows people to lower their antihypertensive medication and improves cardiovascular disease (CVD) risk factors.
Study shows pine bark naturally reduces osteoarthritis
More than 20 million Americans suffer from osteoarthritis, with half a million Americans having a total joint replacement each year.
New research accepted for publication in the Journal of Psychopharmacology, demonstrates Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, improves the memory of senior citizens.
The study results revealed Pycnogenol improved both numerical working memory as well as spatial working memory using a computerized testing system. The research was presented last week at the Oxygen Club of California 2008 World Congress on Oxidants and Antioxidants in Biology in Santa Barbara, CA.
Horphag's Prelox provides over-the-counter solution
For couples worldwide, erectile dysfunction (ED) is one of the leading contributors to a man's inability to perform. As millions of men in America each year look for a solution, many seek alternative treatments to prescription medications and surgery that may have dangerous side effects.
New study: pine bark extract boosts nitric oxide production
A study to be published in the October edition of Hypertension Research reveals Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, helps individuals by enhancing healthy nitric oxide (NO) production which leads to an increase in blood flow and oxygen supply to muscles.
New study: Pine bark extract reduces ADHD symptoms in children
Attention Deficit Hyperactivity Disorder (ADHD) is a prevailing issue in the United States, with millions of children getting diagnosed every year. A new study reveals that Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, reduces ADHD in children.
New study: Pine bark reduces perimenopausal symptoms
A study to be published in an upcoming edition of the Scandinavian Journal of Obstetrics and Gynaecology reveals that Pycnogenol® (pic-noj-en-all), pine bark extract from the French maritime pine tree, reduces "climacteric symptoms" such as hot flashes, depression, panic attacks, cholesterol and other common symptoms associated with women entering menopause transition.
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Source Naturals Pycnogenol, 50mg, Tablets, 120 tablets by Source Naturals Dietary supplement. Proanthocyanidins complex. Pycnogenol is a natural plant product made from the bark of the European coastal pine, Pinus maritima. Pycnogenol is rich in proanthocyanidins, a special class of water-soluble antioxidant flavonoids which are excellent free radical scavengers. Proanthocyanidins are believed to play an important role in maintaining good health. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). |
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Source Naturals Pycnogenol 100mg, 60 tablets by Source Naturals Dietary supplement. Proanthocyanidin complex. Pycnogenol is a natural plant product made from the bark of the European coastal pine, Pinus martima. Pycnogenol is rich in proanthocyanidins, a special class of water-soluble antioxidant flavonoids, which are excellent free radical scavengers. Proanthocyanidins are believed to play an important role in maintaining good health (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). Suitable for vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance. |
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Pycnogenol 100mg 30 Caps by Swanson Ultra Put the antioxidant power of pine to work for you with Pycnogenol! This natural extract from the bark of the French maritime pine tree contains some of the most powerful antioxidant flavonoids ever discovered, making it a great source of free-radical protection for collagen structures in the blood vessels, skin, and joint tissues. Our convenient capsules deliver an ultra-potent 100 mg for high-powered antioxidant protection. |
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TwinLabs Pycnogenol Capsules, 50 Mg, 60-Count Bottle by Twinlab Dietary supplement. Patented natural antioxidant standardized pine bark extract. Well tolerated by most highly allergic individuals. No corn, soy, yeast, milk or egg products. No added sugars, salt (sodium), preservatives or tablet binders and coatings. This product is manufactured at our own state of the art facilities with stringent quality control assuring correct potencies and outstanding product freshness. It is packaged in a glass bottle for maximum stability and quality. |
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Source Naturals Pycnogenol Complex, 120 tablets by Source Naturals Dietary supplement. Antioxidant formula rich in flavonoids, proanthocyanidins & Vitamin C. Pycnogenol Complex combines pycnogenol and proanthodyn (grape seed extract), two potent antioxidants, with eight other plantioxidants (plant-derived antioxidants) to create a natural, power-packed antioxidant supplement. Magnesium ascorbate, a non-acidic form of Vitamin C, adds to the antioxidant activity. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease). |
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Nature's Purest Pine Bark Extract 100 mg /120 caps by Nature's Purest PINE BARK EXTRACT 90%, is a term describing oligomeric proanthocyanidins (OPC), a natural substance derived from the bark of certain pine trees. Studies in the test tube have shown PINE BARK EXTRACT (OPC) to be 50 times more potent than Vitamin E as an antioxidant, and 20 times stronger than Vitamin C. Pine Bark Extract is able to cross the blood barrier of the brain to provide extra protection against free radicals in the nervous system and circulatory system. There is also evidence that Pine Bark Extract provides extra protection for collagen. Pine Bark Extract also frees up Vitamin C to perform its many other important functions.* |
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Natrol Pycnogenol, 50mg Capsules - 60 ea by Natrol Please note: Due to product improvements, the image shown may temporarily appear different from the product received. Beneficial Antioxidant Properties Standardized Pine Bark ExtractPycnogenol® is a natural plant extract made from the bark of Pinus Maritima.Natrol Pycogenol ® contains proanthocyandins, powerful compounds that act as antioxidant, free-radical scavengers.* No yeast, wheat, corn, milk, egg, soy, glutens, artificial colors or flavors, added sugar, starch or preservatives. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Made in USA +Pycnogenol® is a brand of Pine Bark Standardized Extract and a registered trademark of... |
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Now Foods Pycnogenol 30mg, 150 Capsules by NOW Pycnogenol is a concentrated natural extract from the bark of pine trees that grows in this 4,000 square mile forest. These pine trees contain concentrated levels of unique flavonoid compounds that support the body's ability to neutralize free radicals. Free radicals (reactive molecules) can inhibit immune functions and expedite the aging process. * Picture may be of different size or flavor |
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Schiff Pycnogenol, 50 mg, Capsules, 30 capsules (Pack of 2) by Schiff Pycnogenol contains antioxidants isolated by a patented method from French Maritime Pine Bark (Pinus Maritimus). Pycnogenol supports healthy, cardiovascular function by protecting blood vessel lining (endothelial) cells from damage by free radicals. This |
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Pycnogenol 50 mg 50 Caps by Swanson Premium Brand Protect your body against free-radical damage with the natural flavonoid power of Pycnogenol! Derived from the bark of the French maritime pine, Pycnogenol is a water-soluble antioxidant flavonoid extract with highly bioavailable procyanidins, catechins, taxifolins and a wide spectrum of phenolic acids. By providing an optimal combination of these valuable flavonoids in a single, concentrated supplement, Pycnogenol helps the body combat environmental stress while protecting vital collagen structures in the blood vessels, skin and joint tissues against the harmful effects of free radicals. |
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