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Scientists discover new species of Ebola virus
November 21, 2008Scientists report the discovery of a new species of Ebola virus, provisionally named Bundibugyo ebolavirus, November 21 in the open-access journal PLoS Pathogens. The virus, which was responsible for a hemorrhagic fever outbreak in western Uganda in 2007, has been characterized by a team of researchers from the Centers for Disease Control and Prevention in Atlanta, Georgia the Uganda Virus Research Institute; the Uganda Ministry of Health; and Columbia University.
Ebola virus infection in humans causes severe disease for which there is presently no vaccine or other treatment. Case fatalities range historically between 53 and 90%. Therefore, research efforts into the Ebola virus genus and potential diagnostics are ongoing, with the discovery of Bundibugyo ebolavirus representing one of the latest pieces added to this puzzle.
Knowledge of this sequence then allowed for the rapid development of a sensitive molecular detection assay which was deployed to the field as part of the outbreak response. This draft sequence also allowed for easy completion of the whole genome sequence using a traditional primer walking approach and prompt confirmation that this virus represented a new Ebola virus species. Current worldwide efforts to design effective diagnostics, antivirals and vaccines will need to take into account the distinct nature of this new member of the Ebola virus genus.
http://dx.plos.org/10.1371/journal.ppat.1000212
Public Library of Science
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Ebola Virus Current Events and Ebola Virus News RSSScientists block Ebola infection in cell-culture experiments
Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells.
Penn Study Identifies How Ebola Virus Avoids the Immune System
Researchers at the University of Pennsylvania School of Medicine have likely found one reason why the Ebola virus is such a powerful, deadly, and effective virus. Using a cell culture model for Ebola virus infection, they have discovered that the virus disables a cellular protein called tetherin that normally can block the spread of virus from cell to cell.
Iowa State University researchers discover structure of key Ebola protein
Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus.
Scientists uncover Ebola cell-invasion strategy
University of Texas Medical Branch at Galveston researchers have discovered a key biochemical link in the process by which the Ebola Zaire virus infects cells - a critical step to finding a way to treat the deadly disease produced by the virus.
Wildlife Conservation Society discovers 'Planet of the Apes'
The world's population of critically endangered western lowland gorillas received a huge boost today when the Wildlife Conservation Society released a census showing massive numbers of these secretive great apes alive and well in the Republic of Congo.
Scripps research scientists reveal key structure from ebola virus
Described in the July 10, 2008 issue of the journal Nature, the research reveals the shape of the Ebola virus spike protein, which is necessary for viral entry into human cells, bound to an immune system antibody acting to neutralize the virus.
Vaccine for Ebola virus
One of the world's deadliest diseases, caused by the Ebola virus, may finally be preventable thanks to US and Canadian researchers, who have successfully tested several Ebola vaccines in primates and are now looking to adapt them for human use.
Penn scientists find a protein that inhibits Ebola from reaching out to infect neighboring cells
Scientists at the University of Pennsylvania School of Veterinary Medicine have identified a protein, ISG15, that inhibits the Ebola virus from budding, the process by which viruses escape from cells and spread to infect neighboring cells.
Emerging infectious diseases on the rise: Next target 'hotspot' predicted
It's not just your imagination. Providing the first-ever definitive proof, a team of scientists has shown that emerging infectious diseases such as HIV, Severe Acute Respiratory Syndrome (SARS), West Nile virus and Ebola are indeed on the rise.
Study garners unique mating photos of wild gorillas
Scientists from the Wildlife Conservation Society and Max Planck Institute for Evolutionary Anthropology have released the first known photographs of gorillas performing face-to-face copulation in the wild. This is the first time that western gorillas have been observed and photographed mating in such a manner.
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