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Med school discovery could lead to better cancer diagnosis, drugs
November 24, 2008TALLAHASSEE, Fla. -- A Florida State University College of Medicine research team led by Yanchang Wang has discovered an important new layer of regulation in the cell division cycle, which could lead to a greater understanding of the way cancer begins.
Wang, an assistant professor of biomedical sciences at the College of Medicine, said the findings will lead to an improved ability to diagnose cancer and could lead to the design of new drugs that kill cancer cells by inhibiting cell reproduction. His paper on the discovery has been published in the journal Proceedings of the National Academy of Sciences.
"The correct timing of chromosome segregation during cell division is necessary to ensure normal, healthy growth," Wang said. "Now we have discovered a previously undetected layer of regulation in how the chromosomes separate, which helps to ensure the correct timing and decreases the potential for the formation of cancerous growth."
The cell division cycle is a collection of tightly regulated events that lead to cell duplication. The most important events are the doubling of the hereditary information encoded within a set of chromosomes, and the division of that duplicated information into two daughter cells that are genetically identical to each other and the mother cell.
The correct order of cell-cycle events is essential for successful cell division. Wang's article addresses the role of a particular protein enzyme, Cdc14, in ensuring that cell division events occur in exactly the right order.
Defects in the regulation of the order of events can lead to cell death or the alteration of genetic information, which contributes to the formation of cancerous cells.
Florida State University
The cell division cycle is a collection of tightly regulated events that lead to cell duplication. The most important events are the doubling of the hereditary information encoded within a set of chromosomes, and the division of that duplicated information into two daughter cells that are genetically identical to each other and the mother cell.
The correct order of cell-cycle events is essential for successful cell division. Wang's article addresses the role of a particular protein enzyme, Cdc14, in ensuring that cell division events occur in exactly the right order.
Defects in the regulation of the order of events can lead to cell death or the alteration of genetic information, which contributes to the formation of cancerous cells.
Florida State University
Cell Division Current Events and Cell Division News RSSParadoxical protein might prevent cancer
One difficulty with fighting cancer cells is that they are similar in many respects to the body's stem cells. By focusing on the differences, researchers at Karolinska Institutet have found a new way of tackling colon cancer. The study is presented in the prestigious journal Cell.
Study reveals why certain drug combinations backfire
Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and opens the door for another to deliver the deathblow.
Sponges recycle carbon to give life to coral reefs
Coral reefs support some of the most diverse ecosystems on the planet, yet they thrive in a marine desert. So how do reefs sustain their thriving populations?
Researchers discover mechanism that prevents two species from reproducing
Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve.
Common weed could provide clues on aging and cancer
A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from Texas A&M University and the University of Cincinnati (UC).
Boston University scientists first to see RNA network in live bacterial cells
Scientists who study RNA have faced a formidable roadblock: trying to examine RNA's movements in a living cell when they can't see the RNA. Now, a new technology has given scientists the first look ever at RNA in a live bacteria cell-a sight that could offer new information about how the molecule moves and works.
Texas A&M researchers find new mechanism for circadian rhythm
Molecules that may hold the key to new ways to fight cancer and other diseases have been found to play an important role in regulating circadian rhythm, says Liheng Shi, a researcher in Texas A&M's Department of Veterinary Integrative Biosciences.
Checkered history of mother and daughter cells explains cell cycle differences
When mother and daughter cells are created each time a cell divides, they are not exactly alike. They have the same set of genes, but differ in the way they regulate them.
Eutrophication affects diversity of algae
Eutrophication of the seas may have an impact on genetic variation in algae, research at the University of Gothenburg shows.
MDC scientists show how hematopoietic stem cell development is regulated
During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation.
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Teaching Systems Biology Module 4: Cell Division & Metabolism Starring: Standard Deviants Directed By: Standard Deviants The DVD features award-winning Standard Deviants School programming, which will capture your students' attention and make the subject come alive! Content includes a topic based video programming, classroom notes, graphic handouts, quiz, and answer questions plus a fact filled video segment accompanied by quiz and discussion questions. Cerebellum Teaching System equips you with everything you need to succeed where it matter most: the classroom. Topics covered: Cell division, DNA replication, prophase, metaphase, anaphase, telophase, the principle of segregation, the principle of independent assortment, metabolism, photosynthesis, oxidation & reduction. |
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Cell Division and Genetics (Cells and Life) by Robert Snedden (Author) This new edition of a popular series offers an in-depth look at cells throughout the living world, their structure and processes and how they underpin life on earth. Each title focuses on a different aspect of the subject, from single and multicelled organisms to human genetics.The books are fully updated to reflect latest advances in this constantly changing subject. The books contain brief biographies of pioneer scientists and explanations of why they're important. Ethical issues associated with research into cells are examined. | |
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Star Wars Episode V: The Empire Strikes Back Framed Mini Film Cell Presentation by Film Cells Ltd This framed film cell presentation features a cell of hand selected original 35mm film from the movie Star Wars Episode V: The Empire Strikes Back. The film cell is mounted with mini posters/photos from the movie and a nameplate engraved with the title and limited edition number. They are set on an acid free, double matted mounting board and framed in a beautiful black ash effect frame. This highly collectible film cell presentation is limited in number and comes with a certificate guaranteeing the authenticity of the cells. The image shown of the presentation is an example of what the film cell will look like. Please note that every set is unique as they are hand picked from the original film. |
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Cell Division 1: Mitosis & the Cell Cycle by iKnow Use the power of 3-D animation to excite your students about cell division! They will learn the phases of mitosis in animal and plant cells, and the difference between mitosis and cytokinesis. Students can compare and contrast the phases of mitosis in side-by-side plant and animal cell micrographs. Video microscopy makes mitosis come alive in an amphibian lung cell and a zebrafish embryo. The eukaryotic cell cycle is presented in detail in 6 fully narrated animations. Topics covered include: DNA replication and structure, cell cycle variations, molecular control of a cell's progress through the cell cycle, and a discussion of cancer. Students will explore the anatomy of plant, animal, and bacteria cells with interactive diagrams and definitions. Prokaryotic cell division is compared to... |
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SciEd Cell Division: Mitosis, Meiosis, and Cytokinesis VHS Video by Neo/Sci Corporation Video, Cell division; Neo Sci; Mitosis, Meiosis, and Cytokinesis; VHS |
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OL Medical Division Cell-U-Less - 75 Capsules by OL Medical Division Cell-U-Less is a comprehensive herbal remedy consisting of standardized herbs that help to improve circulation, decrease water retention and may enhance connective tissue structures. Impaired circulation, water retention problems and the breakdown and thinning of connective tissue structures are contributing factors to the development of cellulite. The term cellulite is used to describe a condition that is related to hormonal variations and results from circulatory impairments, fluid retention, enlargement of fat cells and alterations in connective tissue. Women are most often affected by cellulite due to structural differences in subcutaneous tissue when compared to men. In women, the subcutaneous tissue contains vertical fat cells that are separated by dividing walls of connective... |
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